Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dominika T. Gruszka"'
Autor:
Allison Ballandras-Colas, Vidya Chivukula, Dominika T. Gruszka, Zelin Shan, Parmit K. Singh, Valerie E. Pye, Rebecca K. McLean, Gregory J. Bedwell, Wen Li, Andrea Nans, Nicola J. Cook, Hind J. Fadel, Eric M. Poeschla, David J. Griffiths, Javier Vargas, Ian A. Taylor, Dmitry Lyumkis, Hasan Yardimci, Alan N. Engelman, Peter Cherepanov
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The authors determined high-resolution cryo-EM structures of the lentiviral intasome — the nucleoprotein complex that inserts viral DNA into a host chromosome — and show that the architecture comprising 16 integrase subunits is critical for its f
Externí odkaz:
https://doaj.org/article/38b768c566d24b6c8e369c087cb41667
Autor:
Emma Pettengale, Dominika T. Gruszka
Publikováno v:
The Biochemist. 43:42-44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8daa94f3cf57df89fe6cea761184a03
https://doi.org/10.1042/bio_2021_158
https://doi.org/10.1042/bio_2021_158
Autor:
Fiona Whelan, Jane Clarke, Jennifer R. Potts, Judith A. Hawkhead, Emanuele Paci, Dominika T. Gruszka, Carolina A.T.F. Mendonça
Many human proteins contain intrinsically disordered regions, and disorder in these proteins can be fundamental to their function - for example, facilitating transient but specific binding, promoting allostery, or allowing efficient posttranslational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b23163677a212631f89e87d93b439ea
https://www.repository.cam.ac.uk/handle/1810/260286
https://www.repository.cam.ac.uk/handle/1810/260286
Autor:
Jennifer R. Potts, Rebecca M. Corrigan, Dominika T. Gruszka, Joan A. Geoghegan, James P. O'Gara, Timothy J. Foster, Pietro Speziale
Publikováno v:
Journal of Bacteriology. 192:5663-5673
The SasG surface protein of Staphylococcus aureus has been shown to promote the formation of biofilm. SasG comprises an N-terminal A domain and repeated B domains. Here we demonstrate that SasG is involved in the accumulation phase of biofilm, a proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcc13318444dba6fa7b87840c270c02
https://doi.org/10.1128/jb.00628-10
https://doi.org/10.1128/jb.00628-10
Autor:
Jennifer R. Potts, Dominika T. Gruszka, Jane Clarke, Richard J. Bingham, Justyna Aleksandra Wojdyla, Timothy J. Foster, Iain W. Manfield, Annette Steward, Johan P. Turkenburg, Andrew P. Leech, Joan A. Geoghegan
Staphylococcus aureus and Staphylococcus epidermidis form communities (called biofilms) on inserted medical devices, leading to infections that affect many millions of patients worldwide and cause substantial morbidity and mortality. As biofilms are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1ed2c7bae609cc92e59a279e0256dc
https://europepmc.org/articles/PMC3340054/
https://europepmc.org/articles/PMC3340054/
Autor:
Emanuele Paci, Fiona Whelan, David J. Brockwell, Dominika T. Gruszka, Jennifer R. Potts, Jane Clarke
Publikováno v:
Biophysical Journal. 108:346a
SasG has a long repeat region made up of identical repeating E and G5 domains. Although the domains themselves are relatively unstable (indeed E domains on their own are unfolded), the cooperative folding of the domains results in formation of molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c439ec9d359e8f0f9a2bc7e9ac9b37b8
https://doi.org/10.1016/j.bpj.2014.11.1897
https://doi.org/10.1016/j.bpj.2014.11.1897
Autor:
Annette Steward, Jennifer C. Lee, Jennifer R. Potts, Jane Clarke, Sarah L. Shammas, Dominika T. Gruszka, Joseph M. Rogers, Stephanie A. Hill
Publikováno v:
Biophysical Journal. 104:189a
Although there have been many thermodynamic studies of the association of intrinsically disordered proteins (IDPs) with their binding partners, there have been relatively few kinetic studies.We have analysed the association of two different IDP syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acde092df44b4c833e10e8fd6405ef57
https://doi.org/10.1016/j.bpj.2012.11.1069
https://doi.org/10.1016/j.bpj.2012.11.1069