Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dominika Chalupská"'
Autor:
Jan Silhan, Martin Klima, Tomas Otava, Petr Skvara, Dominika Chalupska, Karel Chalupsky, Jan Kozic, Radim Nencka, Evzen Boura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Monkeypox is a disease with pandemic potential. It is caused by the monkeypox virus (MPXV), a double-stranded DNA virus from the Poxviridae family, that replicates in the cytoplasm and must encode for its own RNA processing machinery includi
Externí odkaz:
https://doaj.org/article/54fb64d84fe748cfbb69a1da79700d89
Autor:
Nivedita Sengupta, Marko Jović, Elena Barnaeva, David W. Kim, Xin Hu, Noel Southall, Milan Dejmek, Ivana Mejdrova, Radim Nencka, Adriana Baumlova, Dominika Chalupska, Evzen Boura, Marc Ferrer, Juan Marugan, Tamas Balla
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 3, Pp 683-693 (2019)
The minor phospholipid, phosphatidylinositol 4-phosphate (PI4P), is emerging as a key regulator of lipid transfer in ER-membrane contact sites. Four different phosphatidylinositol 4-kinase (PI4K) enzymes generate PI4P in different membrane compartmen
Externí odkaz:
https://doaj.org/article/140be2b4c8d44d3c8e02d4ac3aa65593
Autor:
Dhurvas Chandrasekaran Dinesh, Dominika Chalupska, Jan Silhan, Eliska Koutna, Radim Nencka, Vaclav Veverka, Evzen Boura
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009100 (2020)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is a single-stranded positive-sense RNA virus. Like other coronaviruses, SARS-CoV-2 has an unusually large geno
Externí odkaz:
https://doaj.org/article/ef2781b4c9fc4bd3997b32ca79b65dc0
Autor:
Vladimira Horova, Barbora Landova, Jan Hodek, Karel Chalupsky, Petra Krafcikova, Dominika Chalupska, Vojtech Duchoslav, Jan Weber, Evzen Boura, Martin Klima
Publikováno v:
Viruses, Vol 13, Iss 8, p 1487 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease-19 pandemic. One of the key components of the coronavirus replication complex are the RNA methyltransferases (MTases), RNA-modifying enzyme
Externí odkaz:
https://doaj.org/article/3beeeef5e93940659d181dfbb4333ecf
Autor:
Vladimira Horova, Heyrhyoung Lyoo, Bartosz Różycki, Dominika Chalupska, Miroslav Smola, Jana Humpolickova, Jeroen R P M Strating, Frank J M van Kuppeveld, Evzen Boura, Martin Klima
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007962 (2019)
Enteroviruses, members of the family of picornaviruses, are the most common viral infectious agents in humans causing a broad spectrum of diseases ranging from mild respiratory illnesses to life-threatening infections. To efficiently replicate within
Externí odkaz:
https://doaj.org/article/3c595b6221a645c7b30fb60a680283a1
Autor:
Olivier Terrier, Sébastien Dilly, Andrés Pizzorno, Dominika Chalupska, Jana Humpolickova, Evžen Bouřa, Francis Berenbaum, Stéphane Quideau, Bruno Lina, Bruno Fève, Frédéric Adnet, Michèle Sabbah, Manuel Rosa-Calatrava, Vincent Maréchal, Julien Henri, Anny Slama-Schwok
Publikováno v:
Molecules, Vol 26, Iss 9, p 2593 (2021)
There is an urgent need for specific antiviral treatments directed against SARS-CoV-2 to prevent the most severe forms of COVID-19. By drug repurposing, affordable therapeutics could be supplied worldwide in the present pandemic context. Targeting th
Externí odkaz:
https://doaj.org/article/dab9cc3f495e4edab8a5cc709db997e4
Autor:
Stanislav Kadlčík, Tomáš Kučera, Dominika Chalupská, Radek Gažák, Markéta Koběrská, Dana Ulanová, Jan Kopecký, Eva Kutejová, Lucie Najmanová, Jiří Janata
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84902 (2013)
Clinically used lincosamide antibiotic lincomycin incorporates in its structure 4-propyl-L-proline (PPL), an unusual amino acid, while celesticetin, a less efficient related compound, makes use of proteinogenic L-proline. Biochemical characterization
Externí odkaz:
https://doaj.org/article/83cc7ae4327c40cba4c12fbed16d3349
Autor:
Mbilo Misehe, Martin Klima, Marika Matoušová, Dominika Chalupská, Milan Dejmek, Michal Šála, Helena Mertlíková-Kaiserová, Evzen Boura, Radim Nencka
Publikováno v:
Bioorganicmedicinal chemistry letters. 76
Novel 4-aminoquinazoline-6-carboxamide derivatives bearing differently substituted aryl or heteroaryl groups at position 7 in the core were rationally designed, synthesized and evaluated for biological activity in vitro as phosphatidylinositol 4-kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78faeca1cf0c966918ea490bcbc2bd8f
https://pubmed.ncbi.nlm.nih.gov/36184029
https://pubmed.ncbi.nlm.nih.gov/36184029