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pro vyhledávání: '"Dominik Stammler"'
Autor:
Sabine J. Wölfle, Julia S. Frick, Andre Fischer, Sarah Menz, Melanie R. Shakespear, Judith Knievel, Julian David Langer, Liliana Schaefer, Dominik Stammler, Konrad A. Bode, Jonathan Jantsch, Klaus Heeg, Ina Oehme, Tatjana Eigenbrod, Isabel Siegert, Alexander H. Dalpke, Matthew J. Sweet
Publikováno v:
The journal of immunology 195(11), 5421-5431 (2015). doi:10.4049/jimmunol.1501195
Histone deacetylase (HDAC) inhibitors (HDACi) are clinically approved anticancer drugs that have important immune-modulatory properties. We report the surprising finding that HDACi promote LPS-induced IL-1β processing and secretion in human and muri