Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dominik Possner"'
Autor:
Natalie M. Hendrikse, Anna Sandegren, Tommy Andersson, Jenny Blomqvist, Åsa Makower, Dominik Possner, Chao Su, Niklas Thalén, Agneta Tjernberg, Ulrica Westermark, Johan Rockberg, Stefan Svensson Gelius, Per-Olof Syrén, Erik Nordling
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102154- (2021)
Summary: We show the successful application of ancestral sequence reconstruction to enhance the activity of iduronate-2-sulfatase (IDS), thereby increasing its therapeutic potential for the treatment of Hunter syndrome—a lysosomal storage disease c
Externí odkaz:
https://doaj.org/article/d39df5cce7224dbcaf4d0e1329c50468
Autor:
Åsa Makower, Anna Sandegren, Per-Olof Syrén, Stefan Svensson Gelius, Chao Su, Natalie M. Hendrikse, Dominik Possner, Agneta Tjernberg, Tommy Andersson, Niklas Thalén, Johan Rockberg, Jenny Blomqvist, Erik Nordling, Ulrica Westermark
Publikováno v:
iScience
iScience, Vol 24, Iss 3, Pp 102154-(2021)
iScience, Vol 24, Iss 3, Pp 102154-(2021)
Summary We show the successful application of ancestral sequence reconstruction to enhance the activity of iduronate-2-sulfatase (IDS), thereby increasing its therapeutic potential for the treatment of Hunter syndrome—a lysosomal storage disease ca