Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dominik Possner"'
Autor:
Natalie M. Hendrikse, Anna Sandegren, Tommy Andersson, Jenny Blomqvist, Åsa Makower, Dominik Possner, Chao Su, Niklas Thalén, Agneta Tjernberg, Ulrica Westermark, Johan Rockberg, Stefan Svensson Gelius, Per-Olof Syrén, Erik Nordling
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102154- (2021)
Summary: We show the successful application of ancestral sequence reconstruction to enhance the activity of iduronate-2-sulfatase (IDS), thereby increasing its therapeutic potential for the treatment of Hunter syndrome—a lysosomal storage disease c
Externí odkaz:
https://doaj.org/article/d39df5cce7224dbcaf4d0e1329c50468
Autor:
Åsa Makower, Anna Sandegren, Per-Olof Syrén, Stefan Svensson Gelius, Chao Su, Natalie M. Hendrikse, Dominik Possner, Agneta Tjernberg, Tommy Andersson, Niklas Thalén, Johan Rockberg, Jenny Blomqvist, Erik Nordling, Ulrica Westermark
Publikováno v:
iScience
iScience, Vol 24, Iss 3, Pp 102154-(2021)
iScience, Vol 24, Iss 3, Pp 102154-(2021)
Summary We show the successful application of ancestral sequence reconstruction to enhance the activity of iduronate-2-sulfatase (IDS), thereby increasing its therapeutic potential for the treatment of Hunter syndrome—a lysosomal storage disease ca
Autor:
Thalén NB; Dept. of Protein science, KTH - Royal Institute of Technology, Stockholm, SE-106 91, Sweden., Barzadd MM; Dept. of Protein science, KTH - Royal Institute of Technology, Stockholm, SE-106 91, Sweden., Lundqvist M; Dept. of Protein science, KTH - Royal Institute of Technology, Stockholm, SE-106 91, Sweden., Rodhe J; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Andersson M; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Bidkhori G; Science for Life Laboratory, KTH - Royal Institute of Technology, Solna, 171 65, Sweden; AIVIVO Ltd. Unit 25, Bio-innovation centre, Cambridge Science park, Cambridge, UK., Possner D; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Su C; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Nilsson J; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Eisenhut P; ACIB - Austrian Centre of Industrial Biotechnology, Krenngasse 37, 8010 Graz, Austria; BOKU - University of Natural Resources and Life Sciences, Department of Biotechnology, Vienna, 1190, Austria., Malm M; Dept. of Protein science, KTH - Royal Institute of Technology, Stockholm, SE-106 91, Sweden., Karlsson A; Dept. of Protein science, KTH - Royal Institute of Technology, Stockholm, SE-106 91, Sweden., Vestin J; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Forsberg J; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Nordling E; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Mardinoglu A; Science for Life Laboratory, KTH - Royal Institute of Technology, Solna, 171 65, Sweden., Volk AL; Dept. of Protein science, KTH - Royal Institute of Technology, Stockholm, SE-106 91, Sweden., Sandegren A; SOBI AB, Tomtebodavägen 23A, Stockholm, Sweden., Rockberg J; Dept. of Protein science, KTH - Royal Institute of Technology, Stockholm, SE-106 91, Sweden. Electronic address: johanr@biotech.kth.se.
Publikováno v:
Metabolic engineering [Metab Eng] 2024 Jan; Vol. 81, pp. 157-166. Date of Electronic Publication: 2023 Dec 09.
Autor:
Hendrikse NM; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden.; Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Solna 171 21, Sweden.; Department of Fibre and Polymer Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 100 44, Sweden., Sandegren A; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Andersson T; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Blomqvist J; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Makower Å; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Possner D; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Su C; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Thalén N; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden., Tjernberg A; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Westermark U; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Rockberg J; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden., Svensson Gelius S; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden., Syrén PO; Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Solna 171 21, Sweden.; Department of Fibre and Polymer Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 100 44, Sweden.; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm 10691, Sweden., Nordling E; Swedish Orphan Biovitrum AB, Stockholm 112 76, Sweden.
Publikováno v:
IScience [iScience] 2021 Feb 06; Vol. 24 (3), pp. 102154. Date of Electronic Publication: 2021 Feb 06 (Print Publication: 2021).