Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Dominik P, Modest"'
Autor:
Nathanael Raschzok, Simon Moosburner, Moritz Blank, Felix Krenzien, Georg Lurje, Wenzel Schöning, Igor M. Sauer, Johann Pratschke, Dominik P. Modest, Annika Kurreck
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Multimodal two-stage hepatectomy (mTSH) is used in patients with bilobar colorectal liver metastases (CRLM) that cannot be treated with one surgical procedure due to insufficient future liver remnant. Interval chemotherapy has bee
Externí odkaz:
https://doaj.org/article/9c2f0350e7de4f1788ca33b29e4f6797
Autor:
Isis Lozzi, Alexander Arnold, Matthias Barone, Juliette Claire Johnson, Bruno V Sinn, Johannes Eschrich, Pimrapat Gebert, Ruonan Wang, Mengwen Hu, Linda Feldbrügge, Anja Schirmeier, Anja Reutzel-Selke, Thomas Malinka, Felix Krenzien, Wenzel Schöning, Dominik P Modest, Johann Pratschke, Igor M Sauer, Matthäus Felsenstein
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Background Intrahepatic cholangiocarcinoma (ICC) is a disease with poor prognosis and limited therapeutic options. We investigated the tumor immune microenvironment (TIME) to identify predictors of disease outcome and to explore targets for therapeut
Externí odkaz:
https://doaj.org/article/e0446c6ce3f8424696faa2dce6d8a997
Autor:
Nathanael Raschzok, Simon Moosburner, Moritz Blank, Felix Krenzien, Georg Lurje, Wenzel Schöning, Igor M. Sauer, Johann Pratschke, Dominik P. Modest, Annika Kurreck
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/3446e2ac461442b9a31dd83956360f26
Autor:
Isabella Lurje, Deniz Uluk, Sandra Pavicevic, Minh Duc Phan, Dennis Eurich, Uli Fehrenbach, Dominik Geisel, Timo Alexander Auer, Uwe Pelzer, Dominik Paul Modest, Nathanael Raschzok, Igor Maximilian Sauer, Wenzel Schöning, Frank Tacke, Johann Pratschke, Georg Lurje
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17569-17580 (2023)
Abstract Background Body composition alterations are frequent in patients with cancer or chronic liver disease, but their prognostic value remains unclear in many cancer entities. Objective We investigated the impact of disease aetiology and body com
Externí odkaz:
https://doaj.org/article/e612c31cf2d049a896f001361aaf2580
Autor:
Alexander J. Ohnmacht, Arndt Stahler, Sebastian Stintzing, Dominik P. Modest, Julian W. Holch, C. Benedikt Westphalen, Linus Hölzel, Marisa K. Schübel, Ana Galhoz, Ali Farnoud, Minhaz Ud-Dean, Ursula Vehling-Kaiser, Thomas Decker, Markus Moehler, Matthias Heinig, Volker Heinemann, Michael P. Menden
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Precision medicine has revolutionised cancer treatments; however, actionable biomarkers remain scarce. To address this, we develop the Oncology Biomarker Discovery (OncoBird) framework for analysing the molecular and biomarker landscape of r
Externí odkaz:
https://doaj.org/article/6154ff20ebe74724a6a6c7ebb50722a3
Autor:
Simon Moosburner, MD, Chiara Kettler, Karl H. Hillebrandt, MD, Moritz Blank, Hannes Freitag, Sebastian Knitter, MD, Felix Krenzien, MD, Nora Nevermann, MD, Igor M. Sauer, MD, Dominik P. Modest, MD, Georg Lurje, MD, Robert Öllinger, MD, Wenzel Schöning, MD, Jens Werner, MD, Maximilian Schmeding, MD, Johann Pratschke, MD, Nathanael Raschzok, MD, members of StuDoQ|Liver of Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie/StuDoQ
Publikováno v:
Annals of Surgery Open, Vol 4, Iss 4, p e350 (2023)
Objective:. To compare the outcome of minimally invasive liver surgery (MILS) to open liver surgery (OLS) for resection of colorectal liver metastases (CRLM) on a nationwide level. Background:. Colorectal cancer is the third most common malignancy wo
Externí odkaz:
https://doaj.org/article/568b6fc3243c4c029b550d82e9619bf9
Autor:
Linde Kehmann, Marie-Luise Berres, Maria Gonzalez-Carmona, Dominik P. Modest, Raphael Mohr, Alexander Wree, Marino Venerito, Christian Strassburg, Verena Keitel, Christian Trautwein, Tom Luedde, Christoph Roderburg
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The prognosis of patients with advanced biliary tract cancer (BTC) who have progressed on gemcitabine plus cisplatin is dismal. Trifluridine/tipiracil (FTD/TPI) and irinotecan have proven efficacy in different gastrointestinal mal
Externí odkaz:
https://doaj.org/article/adcfd14080b94e43bba7e5c89b37d3ba
Autor:
Nathanael Raschzok, Sebastian Stintzing, Volker Heinemann, Geraldine Rauch, Jens Ricke, Matthias Guckenberger, Annika Kurreck, Annabel H. S. Alig, Arndt Stahler, Lars Bullinger, Moritz Schmelzle, Wenzel Schöning, Georg Lurje, Felix Krenzien, Oliver Haase, Beate Rau, Bernhard Gebauer, Igor M. Sauer, Johann Pratschke, Dominik P. Modest
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Additive/adjuvant chemotherapy as concept after local treatment of colorectal metastases has not been proven to be successful by phase III trials. Accordingly, a standard of care to improve relapse rates and long-term survival is
Externí odkaz:
https://doaj.org/article/55d7920af6364e2ab185a5a9e624c46b
Autor:
Peter Wust, Marcus Beck, Robert Dabrowski, Oliver Neumann, Sebastian Zschaeck, David Kaul, Dominik P. Modest, Carmen Stromberger, Bernhard Gebauer, Pirus Ghadjar
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Several radiotherapeutic approaches for patients with oligotopic malignant liver lesions unfit for surgical resection exist. The most advanced competitive techniques are high-dose-rate (HDR) brachytherapy, Cyberknife, volume-modul
Externí odkaz:
https://doaj.org/article/2d219c5ab8a64b6e9e31f293db927ec1
Autor:
Annika Kurreck, Volker Heinemann, Ludwig Fischer von Weikersthal, Thomas Decker, Florian Kaiser, Jens Uhlig, Michael Schenk, Jens Freiberg-Richter, Bettina Peuser, Claudio Denzlinger, Ullrich Graeven, Kathrin Heinrich, Swantje Held, Arndt Stahler, Annabel Helga Sophie Alig, Ivan Jelas, Jobst C. von Einem, Sebastian Stintzing, Clemens Giessen-Jung, Dominik P. Modest
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionEarly tumor shrinkage (ETS), depth of response (DpR), and time to DpR represent exploratory endpoints that may serve as early efficacy parameters and predictors of long-term outcome in metastatic colorectal cancer (mCRC). We analyzed thes
Externí odkaz:
https://doaj.org/article/02c58eab2dbe4e41985915f0822765da