Zobrazeno 1 - 10
of 424
pro vyhledávání: '"Dominik N, Müller"'
Autor:
Gregor Liegl, Felix H. Fischer, Carl N. Martin, Maria Rönnefarth, Annelie Blumrich, Michael Ahmadi, Leif-Hendrik Boldt, Kai-Uwe Eckardt, Matthias Endres, Frank Edelmann, Holger Gerhardt, Ulrike Grittner, Arash Haghikia, Norbert Hübner, Ulf Landmesser, David Leistner, Knut Mai, Jil Kollmus-Heege, Dominik N. Müller, Christian H. Nolte, Sophie K. Piper, Kai M. Schmidt-Ott, Tobias Pischon, Simrit Rattan, Ira Rohrpasser-Napierkowski, Katharina Schönrath, Jeanette Schulz-Menger, Oliver Schweizerhof, Joachim Spranger, Joachim E. Weber, Martin Witzenrath, Sein Schmidt, Matthias Rose
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Health-related quality of life (HRQL) has become an important outcome parameter in cardiology. The MOS 36-ltem Short-Form Health Survey (SF-36) and the PROMIS-29 are two widely used generic measures providing composite HRQL scores
Externí odkaz:
https://doaj.org/article/e16e431aec684125985e3087cdefce6b
Autor:
Yubei He, Han Xu, Yu Liu, Stefan Kempa, Carolina Vechiatto, Robin Schmidt, Emine Yaren Yilmaz, Luisa Heidemann, Jörg Schnorr, Susanne Metzkow, Eyk Schellenberger, Akvile Häckel, Andreas Patzak, Dominik N. Müller, Lynn Jeanette Savic
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1024 (2024)
M2-like macrophages promote tumor growth and cancer immune evasion. This study used an in vitro model to investigate how hypoxia and tumor metabolism affect macrophage polarization. Liver cancer cells (HepG2 and VX2) and macrophages (THP1) were cultu
Externí odkaz:
https://doaj.org/article/baa06b2c54e248babdc317489ba6fbd0
Autor:
Ulrike Grittner, Ulf Landmesser, Matthias Endres, David M Leistner, Burkert Pieske, Kai-Uwe Eckardt, Joachim Spranger, Jeanette Schulz-Menger, Sophie K Piper, Martin Witzenrath, Geraldine Rauch, Sein Schmidt, Vasan S Ramachandran, Christian H Nolte, Tobias Pischon, Dominik N Müller, Frank Edelmann, Leif-Hendrik Boldt, Norbert Hubner, Kai M Schmidt-Ott, Bob Siegerink, Joachim E Weber, Michael Ahmadi, Holger Gerhardt, Kathrin Haubold, Jil Kollmus-Heege, Knut Mai, Simrit Rattan, Katharina Schönrath, Oliver Schweizerhof
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction The Berlin Long-term Observation of Vascular Events is a prospective cohort study that aims to improve prediction and disease-overarching mechanistic understanding of cardiovascular (CV) disease progression by comprehensively investigati
Externí odkaz:
https://doaj.org/article/6928f849c2c5480ebd61b441aa81f6d7
Autor:
András Maifeld, Hendrik Bartolomaeus, Ulrike Löber, Ellen G. Avery, Nico Steckhan, Lajos Markó, Nicola Wilck, Ibrahim Hamad, Urša Šušnjar, Anja Mähler, Christoph Hohmann, Chia-Yu Chen, Holger Cramer, Gustav Dobos, Till Robin Lesker, Till Strowig, Ralf Dechend, Danilo Bzdok, Markus Kleinewietfeld, Andreas Michalsen, Dominik N. Müller, Sofia K. Forslund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nutritional modification including fasting has been shown to reduce cardiometabolic risk linked to western diet. Here the authors show implementation of fasting resulted in alterations to the intestinal microbiota, and circulating immune cells, impro
Externí odkaz:
https://doaj.org/article/bd88210111b3471db56e63937c180035
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Arterial hypertension is a major risk factor for cardiovascular disease and leads to target organ damage including stroke, heart failure, and kidney disease. About 1.5 billion people worldwide have hypertension, and it is estimate
Externí odkaz:
https://doaj.org/article/3e70792260a44b869798b14110c6ede9
Autor:
Stefanie Haase, Jonas Mäurer, Alexander Duscha, De-Hyung Lee, Andras Balogh, Ralf Gold, Dominik N. Müller, Aiden Haghikia, Ralf A. Linker
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
High-fat diets (HFD) are linked to obesity and associated comorbidities and induce pathogenic T helper (Th) 17 cells while decreasing regulatory T cells (Treg). This pro-inflammatory environment also aggravates immunopathology in experimental autoimm
Externí odkaz:
https://doaj.org/article/c0717e3e67774de5b18256d483a3f4a5
Autor:
Otavio Cabral-Marques, Alexandre Marques, Lasse Melvær Giil, Roberta De Vito, Judith Rademacher, Jeannine Günther, Tanja Lange, Jens Y. Humrich, Sebastian Klapa, Susanne Schinke, Lena F. Schimke, Gabriele Marschner, Silke Pitann, Sabine Adler, Ralf Dechend, Dominik N. Müller, Ioana Braicu, Jalid Sehouli, Kai Schulze-Forster, Tobias Trippel, Carmen Scheibenbogen, Annetine Staff, Peter R. Mertens, Madlen Löbel, Justin Mastroianni, Corinna Plattfaut, Frank Gieseler, Duska Dragun, Barbara Elizabeth Engelhardt, Maria J. Fernandez-Cabezudo, Hans D. Ochs, Basel K. al-Ramadi, Peter Lamprecht, Antje Mueller, Harald Heidecke, Gabriela Riemekasten
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Autoantibodies are implicated in autoimmunity, but may also be present in healthy individuals. Here the authors find that the autoantibody specificity signatures against various G protein-coupled receptors are associated with multiple parameters, inc
Externí odkaz:
https://doaj.org/article/ce22418439234ad18d21d372dba2db52
Autor:
Diana M. Willmes, Martin Daniels, Anica Kurzbach, Stefanie Lieske, Nicole Bechmann, Tina Schumann, Christine Henke, Nermeen N. El-Agroudy, Andrey C. Da Costa Goncalves, Mirko Peitzsch, Anja Hofmann, Waldemar Kanczkowski, Kristin Kräker, Dominik N. Müller, Henning Morawietz, Andreas Deussen, Michael Wagner, Ali El-Armouche, Stephen L. Helfand, Stephan R. Bornstein, Rafael de Cabo, Michel Bernier, Graeme Eisenhofer, Jens Tank, Jens Jordan, Andreas L. Birkenfeld
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Reduced expression of the plasma membrane citrate transporter INDY (acronym I’m Not Dead, Yet) extends life span in lower organisms. Deletion of the mammalian Indy (mIndy) gene in rodents improves metabolism via mechanisms akin to caloric restricti
Externí odkaz:
https://doaj.org/article/30014d99d79f40108541ed9b57e5e2ec
Autor:
Patrick Neubert, Arne Homann, David Wendelborn, Anna-Lorena Bär, Luka Krampert, Maximilian Trum, Agnes Schröder, Stefan Ebner, Andrea Weichselbaum, Valentin Schatz, Peter Linz, Roland Veelken, Jonas Schulte-Schrepping, Anna C Aschenbrenner, Thomas Quast, Christian Kurts, Sabrina Geisberger, Karl Kunzelmann, Karin Hammer, Katrina J Binger, Jens Titze, Dominik N Müller, Waldemar Kolanus, Joachim L Schultze, Stefan Wagner, Jonathan Jantsch
Publikováno v:
PLoS Biology, Vol 18, Iss 6, p e3000722 (2020)
Inflammation and infection can trigger local tissue Na+ accumulation. This Na+-rich environment boosts proinflammatory activation of monocyte/macrophage-like cells (MΦs) and their antimicrobial activity. Enhanced Na+-driven MΦ function requires the
Externí odkaz:
https://doaj.org/article/3249cb09b6b04812ba5cea7c7d2e59d9
Autor:
Anna Hammer, Anne Schliep, Stefanie Jörg, Aiden Haghikia, Ralf Gold, Markus Kleinewietfeld, Dominik N. Müller, Ralf A. Linker
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-9 (2017)
Abstract Background There has been a marked increase in the incidence of autoimmune diseases like multiple sclerosis (MS) in the last decades which is most likely driven by a change in environmental factors. Here, growing evidence suggests that ingre
Externí odkaz:
https://doaj.org/article/94c7adf7e5824c2f9f47788971bad708