Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dominik M. Duelli"'
Autor:
Jessica L. Centa, Frank Rigo, Francine M. Jodelka, Anthony J. Hinrich, Joseph Ochaba, Dominik M. Duelli, Michaela Jackson, Tyler B. Johnson, Jill M. Weimer, Michelle L. Hastings
Publikováno v:
Nat Med
CLN3 Batten disease is an autosomal recessive, neurodegenerative, lysosomal storage disease caused by mutations in CLN3, which encodes a lysosomal membrane protein(1–3). There are no disease-modifying treatments for this disease that affects up to
Autor:
Dominik M. Duelli, K. Dale Noel
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 10, Iss 7, Pp 903-910 (1997)
Exudates released from germinating seeds and roots of a black-seeded bean (Phaseolus vulgaris cv. Midnight Black Turtle Soup) induce an antigenic change in the lipopolysaccharide (LPS) of Rhizobium etli CE3. By spectroscopic analyses and chromatograp
Externí odkaz:
https://doaj.org/article/9ce038a7aa434663bffb5124ac528d02
Autor:
Lucy Pigati, Sree C S Yaddanapudi, Ravi Iyengar, Dong-Ja Kim, Steven A Hearn, David Danforth, Michelle L Hastings, Dominik M Duelli
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13515 (2010)
MicroRNAs (miRNAs) in body fluids are candidate diagnostics for a variety of conditions and diseases, including breast cancer. One premise for using extracellular miRNAs to diagnose disease is the notion that the abundance of the miRNAs in body fluid
Externí odkaz:
https://doaj.org/article/11f85bc12ee8492281871fe59308c9f5
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e538 (2007)
Pre-mRNA splicing is a crucial step in gene expression, and accurate recognition of splice sites is an essential part of this process. Splice sites with weak matches to the consensus sequences are common, though it is not clear how such sites are eff
Externí odkaz:
https://doaj.org/article/c42ccf8bc4d147659db3996c7bfc3814
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 4:247-266
Splicing of pre-messenger RNA into mature messenger RNA is an essential step for the expression of most genes in higher eukaryotes. Defects in this process typically affect cellular function and can have pathological consequences. Many human genetic
Autor:
Sarah Jeong, Mallory A. Havens, Brittany Stern, Scree C Yaddanapudi, Lucy Pigati, Kristina Weimer, Jaime Palma, Geoffrey Weiner, Michelle L. Hastings, Dominik M. Duelli
Publikováno v:
Nucleic Acids Research
MicroRNAs (miRNAs) are released from cells in association with proteins or microvesicles. We previously reported that malignant transformation changes the assortment of released miRNAs by affecting whether a particular miRNA species is released or re
Publikováno v:
Nucleic Acids Research
Canonical microRNA biogenesis requires the Microprocessor components, Drosha and DGCR8, to generate precursor-miRNA, and Dicer to form mature miRNA. The Microprocessor is not required for processing of some miRNAs, including mirtrons, in which splice
Publikováno v:
Human Molecular Genetics
Spinal muscular atrophy (SMA) is a neurological disorder characterized by motor neuron degeneration and progressive muscle paralysis. The disease is caused by a reduction in survival of motor neuron (SMN) protein resulting from homozygous deletion of
Autor:
Yuri Lazebnik, Dominik M. Duelli
Publikováno v:
Nature Reviews Cancer. 7:968-976
The ability to fuse cells is shared by many viruses, including common human pathogens and several endogenous viruses. Here we will discuss how cell fusion can link viruses to cancer, what types of cancers it can affect, how the existence of this link
Autor:
Andrew C. Warner, David N. Danforth, Thomas Ried, Darawalee Wangsa, Sheila A. Prindiville, Dominik M. Duelli, Armando C. Filie
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 9 (2015)
Breast Cancer : Basic and Clinical Research
Breast Cancer: Basic and Clinical Research, Vol 2015, Iss 9, Pp 31-40 (2015)
Breast Cancer : Basic and Clinical Research
Breast Cancer: Basic and Clinical Research, Vol 2015, Iss 9, Pp 31-40 (2015)
Background There is a strong need to define the molecular changes in normal at-risk breast epithelium to identify biomarkers and new targets for breast cancer prevention and to develop a molecular signature for risk assessment. Improved methods of br