Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dominik Kiemel"'
Autor:
Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J. F. Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf Bartenschlager
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Dengue fever represents a significant medical and socio-economic burden in (sub)tropical regions, yet antivirals for treatment or prophylaxis are lacking. JNJ-A07 was described as highly active against the different genotypes within each ser
Externí odkaz:
https://doaj.org/article/e78ff1b130a7428d836ca61a6614a777
Autor:
Matias Mosqueira, Lisa-Mareike Scheid, Dominik Kiemel, Talisa Richardt, Mona Rheinberger, Dirk Ollech, Almut Lutge, Tim Heißenberg, Lena Pfitzer, Lisa Engelskircher, Umut Yildiz, Isabel Porth
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Nitric oxide (NO) is a bioactive gas produced by one of the three NO synthases: neuronal NOS (nNOS), inducible (iNOS), and endothelial NOS (eNOS). NO has a relevant modulatory role in muscle contraction; this takes place through two major signaling p
Externí odkaz:
https://doaj.org/article/d55d9c76e9fa4c4fab19aa7731881d0d
Autor:
Olivia Goethals, Suzanne J. F. Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J. Verschoor, Babs E. Verstrepen, Zahra Fagrouch, J. Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K. McCracken, Gregory D. Gromowski, Wiriya Rutvisuttinunt, Richard G. Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier de Lamballerie, Laurent Chatel-Chaix, Gregg N. Milligan, David W. C. Beasley, Nigel Bourne, Alan D. T. Barrett, Arnaud Marchand, Tim H. M. Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf Bartenschlager, Willy M. Bogers, Johan Neyts, Marnix Van Loock
Publikováno v:
Nature. 615:678-686
Dengue is a major health threat and the number of symptomatic infections caused by the four dengue serotypes is estimated to be 96 million1 with annually around 10,000 deaths2. However, no antiviral drugs are available for the treatment or prophylaxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8c0a4183f19bf33ac0d110d21b457f
https://doi.org/10.1038/s41586-023-05790-6
https://doi.org/10.1038/s41586-023-05790-6
Autor:
Bart Rudolf Romanie Kesteleyn, Suzanne J.F. Kaptein, Xavier de Lamballerie, Kenny Simmen, Arnaud Marchand, Jean-François Bonfanti, Max Münster, Laurent Chatel-Chaix, Marjolein Crabbe, Johan Neyts, Marnix Van Loock, Kai Dallmeier, Gilles Querat, Franck Touret, Kim Thys, Olivia Goethals, Dorothée Bardiot, Tim H. M. Jonckers, Pierre Jean-Marie Bernard Raboisson, Peggy Geluykens, Dominik Kiemel, Patrick Chaltin, Bart Stoops, Ralf Bartenschlager
Dengue virus causes approximately 96 million symptomatic infections annually, manifesting as dengue fever or occasionally as severe dengue1,2. There are no antiviral agents available to prevent or treat dengue. Here, we describe a highly potent dengu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0f695891d12a95fecae329bcce0424
https://lirias.kuleuven.be/handle/123456789/683277
https://lirias.kuleuven.be/handle/123456789/683277
Autor:
Suzanne J F, Kaptein, Olivia, Goethals, Dominik, Kiemel, Arnaud, Marchand, Bart, Kesteleyn, Jean-François, Bonfanti, Dorothée, Bardiot, Bart, Stoops, Tim H M, Jonckers, Kai, Dallmeier, Peggy, Geluykens, Kim, Thys, Marjolein, Crabbe, Laurent, Chatel-Chaix, Max, Münster, Gilles, Querat, Franck, Touret, Xavier, de Lamballerie, Pierre, Raboisson, Kenny, Simmen, Patrick, Chaltin, Ralf, Bartenschlager, Marnix, Van Loock, Johan, Neyts
Publikováno v:
Nature. 598(7881)
Dengue virus causes approximately 96 million symptomatic infections annually, manifesting as dengue fever or occasionally as severe dengue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4e1de640eac35dd21665b2d7bca5ffa
https://pubmed.ncbi.nlm.nih.gov/34697477
https://pubmed.ncbi.nlm.nih.gov/34697477
Autor:
Davide Barreca, Walter E. Haefeli, Dominik Kiemel, Nicolas Hohmann, Gerd Mikus, Vedat Schwenger, Dirk Theile, Johanna Weiss, Giuseppe Gattuso
Publikováno v:
European Journal of Pharmaceutical Sciences. 97:247-256
Adverse drug interactions due to grapefruit juice are well known prompting warnings even in drug labels. Similar issues have not been reported for clementines and available data is scarce, despite of genetic descent. We observed substantially increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d6987da37257e522401330b398a190
https://doi.org/10.1016/j.ejps.2016.11.021
https://doi.org/10.1016/j.ejps.2016.11.021
Autor:
Siwei Chen, Manon Aïssi, Deng Chen, Frank J. Dekker, Hidde J. Haisma, Dominik Kiemel, Anouk La Rose, Fangyuan Cao, Martijn R. H. Zwinderman, Bin Liu
Publikováno v:
Nucleic Acids Research, 48(2), 517-532. Oxford University Press
Nucleic Acids Research
Nucleic Acids Research
Despite the rapid development of CRISPR/Cas9-mediated gene editing technology, the gene editing potential of CRISPR/Cas9 is hampered by low efficiency, especially for clinical applications. One of the major challenges is that chromatin compaction ine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fe8fa74f19d11313c7519f17540dcf