Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dominik J, Fiegle"'
Autor:
Joachim Greiner, Teresa Schiatti, Wenzel Kaltenbacher, Marica Dente, Alina Semenjakin, Thomas Kok, Dominik J. Fiegle, Thomas Seidel, Ursula Ravens, Peter Kohl, Rémi Peyronnet, Eva A. Rog-Zielinska
Publikováno v:
Cells, Vol 13, Iss 12, p 1034 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/956a8232dedf41df971a0bb4a960e6a9
Autor:
Maximilian J. Klumm, Christian Heim, Dominik J. Fiegle, Michael Weyand, Tilmann Volk, Thomas Seidel
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/ef523fd322ef49a8b6e8c37f094b4ac0
Autor:
Maximilian J. Klumm, Christian Heim, Dominik J. Fiegle, Michael Weyand, Tilmann Volk, Thomas Seidel
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Organotypic culture of human ventricular myocardium is emerging in basic and translational cardiac research. However, few institutions have access to human ventricular tissue, whereas atrial tissue is more commonly available and important for studyin
Externí odkaz:
https://doaj.org/article/5dcb4706b80444bfb867673fec4b8afb
Autor:
Dominik J. Fiegle, Martin Schöber, Sven Dittrich, Robert Cesnjevar, Karin Klingel, Tilmann Volk, Muhannad Alkassar, Thomas Seidel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2021)
Chronic heart failure (HF) in adults causes remodeling of the cardiomyocyte transverse tubular system (t-system), which contributes to disease progression by impairing excitation-contraction (EC) coupling. However, it is unknown if t-system remodelin
Externí odkaz:
https://doaj.org/article/056bb8371e404dfeb4cf5a8c080d88c7
Autor:
Maha Abu-Khousa, Dominik J. Fiegle, Sophie T. Sommer, Ghazali Minabari, Hendrik Milting, Christian Heim, Michael Weyand, Roland Tomasi, Andreas Dendorfer, Tilmann Volk, Thomas Seidel
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The normally positive cardiac force-frequency relationship (FFR) becomes flat or negative in chronic heart failure (HF). Here we explored if remodeling of the cardiomyocyte transverse tubular system (t-system) is associated with alterations in FFR an
Externí odkaz:
https://doaj.org/article/78ea67220bcb4439b18b746f91e17008
Autor:
Joachim Greiner, Teresa Schiatti, Wenzel Kaltenbacher, Marica Dente, Alina Semenjakin, Thomas Kok, Dominik J. Fiegle, Thomas Seidel, Ursula Ravens, Peter Kohl, Rémi Peyronnet, Eva A. Rog-Zielinska
Publikováno v:
Cells, Vol 11, Iss 2, p 233 (2022)
Freshly isolated primary cardiomyocytes (CM) are indispensable for cardiac research. Experimental CM research is generally incompatible with life of the donor animal, while human heart samples are usually small and scarce. CM isolation from animal he
Externí odkaz:
https://doaj.org/article/d8f11d17c7f7419ba4ed0dd7788ddbbd
Autor:
Tilmann Volk, Hendrik Milting, Dominik J Fiegle, S. Sommer, Christian Heim, Anne Ritzer, Thomas Seidel, Andreas Dendorfer
Publikováno v:
The Thoracic and Cardiovascular Surgeon.
Publikováno v:
Journal of Visualized Experiments.
The isolation of ventricular cardiac myocytes from animal and human hearts is a fundamental method in cardiac research. Animal cardiomyocytes are commonly isolated by coronary perfusion with digestive enzymes. However, isolating human cardiomyocytes
Autor:
Maha, Abu-Khousa, Dominik J, Fiegle, Sophie T, Sommer, Ghazali, Minabari, Hendrik, Milting, Christian, Heim, Michael, Weyand, Roland, Tomasi, Andreas, Dendorfer, Tilmann, Volk, Thomas, Seidel
Publikováno v:
Frontiers in Physiology
The normally positive cardiac force-frequency relationship (FFR) becomes flat or negative in chronic heart failure (HF). Here we explored if remodeling of the cardiomyocyte transverse tubular system (t-system) is associated with alterations in FFR an
Autor:
Dominik J Fiegle, Tim J Baur, Hendrik Milting, Thomas Seidel, Tilmann Volk, John A. Cidlowski, Sandra Nay, Michael Weyand, Anne Ritzer, Robert H. Oakley, Christian Heim
Publikováno v:
Basic Res Cardiol
A major contributor to contractile dysfunction in heart failure is remodelling and loss of the cardiomyocyte transverse tubular system (t-system), but underlying mechanisms and signalling pathways remain elusive. It has been shown that dexamethasone