Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Dominik Fröhlich"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Aminoacyl-tRNA synthetases (ARSs) play an essential role in protein synthesis, being responsible for ligating tRNA molecules to their corresponding amino acids in a reaction known as ‘tRNA aminoacylation’. Separate ARSs carry out the aminoacylati
Externí odkaz:
https://doaj.org/article/74ee165049d84cc4a75ed4f3764eaf56
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Protein synthesis is a fundamental process that underpins almost every aspect of cellular functioning. Intriguingly, despite their common function, recessive mutations in aminoacyl-tRNA synthetases (ARSs), the family of enzymes that pair tRNA molecul
Externí odkaz:
https://doaj.org/article/80a5fd1bf33f4523b9bf2b149c7730ec
Autor:
Alexander Weigand, Szilárd-Lehel Bücs, Stanimira Deleva, Lada Lukić Bilela, Pierrette Nyssen, Kaloust Paragamian, Axel Ssymank, Hannah Weigand, Valerija Zakšek, Maja Zagmajster, Gergely Balázs, Shalva Barjadze, Katharina Bürger, William Burn, Didier Cailhol, Amélie Decrolière, Ferdinando Didonna, Azdren Doli, Tvrtko Drazina, Joerg Dreybrodt, Lana Ðud, Csaba Egri, Markus Erhard, Sašo Finžgar, Dominik Fröhlich, Grant Gartrell, Suren Gazaryan, Michel Georges, Jean-Francois Godeau, Ralf Grunewald, John Gunn, Jeff Hajenga, Peter Hofmann, Lee Knight, Hannes Köble, Nikolina Kuharic, Christian Lüthi, Cristian Munteanu, Rudjer Novak, Dainis Ozols, Matija Petkovic, Fabio Stoch, Bärbel Vogel, Ines Vukovic, Meredith Hall Weberg, Christian Zaenker, Stefan Zaenker, Ute Feit, Jean-Claude Thies
Publikováno v:
Research Ideas and Outcomes, Vol 8, Iss , Pp 1-16 (2022)
This manuscript summarizes the outcomes of the 6th EuroSpeleo Protection Symposium. Special emphasis was laid on presenting and discussing monitoring activities under the umbrella of the Habitats Directive (EU Council Directive 92/43/EEC) for habitat
Externí odkaz:
https://doaj.org/article/8e84bdfc549448b4a03d4dcd813d5155
Autor:
Dominik Fröhlich, Elizabeth Kalotay, Georg von Jonquieres, Andre Bongers, Brendan Lee, Alexandra K. Suchowerska, Gary D. Housley, Matthias Klugmann
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The leukodystrophy Canavan disease is a fatal white matter disorder caused by loss-of-function mutations of the aspartoacylase-encoding ASPA gene. There are no effective treatments available and experimental gene therapy trials have failed to provide
Externí odkaz:
https://doaj.org/article/537c8c0bb7154f5697810c52b8705019
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/61bec3b8b3ad42ddb16ab315caae1b59
Autor:
Dirk Lenzen, Jingjing Zhao, Sebastian-Johannes Ernst, Mohammad Wahiduzzaman, A. Ken Inge, Dominik Fröhlich, Hongyi Xu, Hans-Jörg Bart, Christoph Janiak, Stefan Henninger, Guillaume Maurin, Xiaodong Zou, Norbert Stock
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Ultra-low-temperature-actuated adsorption-driven chillers that rely on water as the cooling agent are desirable for energy-efficient and environmentally benign cooling devices. Here the authors show that the metal–organic framework of composition [
Externí odkaz:
https://doaj.org/article/14ae598223154c8e8223203249d0532f
Autor:
Dominik Fröhlich, Marisa I. Mendes, Andrew J. Kueh, Andre Bongers, Marco J. Herold, Gajja S. Salomons, Gary D. Housley, Matthias Klugmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL) is a leukodystrophy caused by missense mutations of the aspartyl-tRNA synthetase-encoding gene DARS1. The clinical picture includes the regression of acquired motor
Externí odkaz:
https://doaj.org/article/2a471b43f5584d4da9624c90395f5e86
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Aminoacyl-tRNA synthetases (ARSs) accurately charge tRNAs with their respective amino acids. As such, they are vital for the initiation of cytosolic and mitochondrial protein translation. These enzymes have become increasingly scrutinized in recent y
Externí odkaz:
https://doaj.org/article/64b1ddd3a3284c518b9b22ad3651923e
Autor:
Carsten Frühbeis, Wen Ping Kuo-Elsner, Christina Müller, Kerstin Barth, Leticia Peris, Stefan Tenzer, Wiebke Möbius, Hauke B Werner, Klaus-Armin Nave, Dominik Fröhlich, Eva-Maria Krämer-Albers
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000621 (2020)
Neurons extend long axons that require maintenance and are susceptible to degeneration. Long-term integrity of axons depends on intrinsic mechanisms including axonal transport and extrinsic support from adjacent glial cells. The mechanisms of support
Externí odkaz:
https://doaj.org/article/e9c8c23d61514c4f9b67e99a6e677aa3
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Recent studies on extracellular RNA raised awareness that extracellular vesicles (EVs) isolated from cultured cells may co-purify RNAs derived from media supplements such as fetal bovine serum (FBS) confounding EV-associated RNA. Defined culture medi
Externí odkaz:
https://doaj.org/article/676da0e32caf4d59b9e2cdc8e700d4c0