Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dominik Eichin"'
Autor:
Tamiko Ishizu, Dominik Eichin, Artur Padzik, Sanni Tuominen, Reidar Grénman, Marko Salmi, Tove J. Grönroos, Johanna M. Tuomela
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background A low tissue oxygen level,
Externí odkaz:
https://doaj.org/article/cac31ac4ef344e469ea3e5f82f8ce4d3
Autor:
Sina Tadayon, Johannes Dunkel, Akira Takeda, Dominik Eichin, Reetta Virtakoivu, Kati Elima, Sirpa Jalkanen, Maija Hollmén
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Clever-1 also known as Stabilin-1 and FEEL-1 is a scavenger molecule expressed on a subpopulation of anti-inflammatory macrophages and lymphatic endothelial cells (LECs). However, its role in regulating dendritic cell (DC) trafficking and subsequent
Externí odkaz:
https://doaj.org/article/b912dbea9876440c957e4e76771e9101
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134721 (2015)
The ectoenzyme CD73 catalyzes the hydrolysis of AMP, and is one of the most important producers of extracellular adenosine. On regulatory T cells, CD73 is necessary for immunosuppressive functions, and on Th17 cells CD73-generated adenosine exerts an
Externí odkaz:
https://doaj.org/article/d130fa4c9762479b833b088925e5f4ff
Autor:
Matthias Mehling, Stefanie Fritz, Patricia Hafner, Dominik Eichin, Tomomi Yonekawa, Thomas Klimkait, Raija L P Lindberg, Ludwig Kappos, Christoph Hess
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78532 (2013)
BACKGROUND: Interferon-beta (IFNβ) regulates the expression of a complex set of pro- as well as anti-inflammatory genes. In cohorts of MS patients unstratified for therapeutic response to IFNβ, normal vaccine-specific immune responses have been obs
Externí odkaz:
https://doaj.org/article/1e598876aa4640fea32a1892b950e19c
Autor:
Marko Salmi, Dominik Eichin, Tove J. Grönroos, Artur Padzik, Reidar Grénman, Johanna Tuomela, Tamiko Ishizu, Sanni Tuominen
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer
BMC Cancer
Background A low tissue oxygen level, 2, is a typical characteristic inside of solid tumors in head and neck cancer (HNSCC) affecting a wide array of cell populations, such as macrophages. However, the mechanisms of how hypoxia influences macrophages
Autor:
Yu Cao, Jian Yang, Dominik Eichin, Fangzhe Zhao, Dawei Qi, Laura Kahari, Chunman Jia, Markus Peurla, Jessica M. Rosenholm, Zhao Zhao, Sirpa Jalkanen, Jianwei Li
Publikováno v:
Angewandte Chemie. 133:3099-3107
Autor:
Tove J. Grönroos, Eliisa Löyttyniemi, Johan Rajander, Thomas Keller, Dominik Eichin, Jouko Sandholm, Sanni Tuominen, Nataliia Petruk, Johanna Tuomela, Alejandra Verhassel, Francisco R. López-Picón
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Background Many malignant tumours have increased TSPO expression, which has been related to a poor prognosis. TSPO-PET tracers have not comprehensively been evaluated in peripherally located tumours. This study aimed to evaluate whether N,N-diethyl-2
Autor:
Fangzhe Zhao, Jianwei Li, Dominik Eichin, Dawei Qi, Yu Cao, Jian Yang, Zhao Zhao, Markus Peurla, Laura Kähäri, Chunman Jia, Sirpa Jalkanen, Jessica M. Rosenholm
Publikováno v:
Angewandte Chemie (International ed. in English). 60(6)
Molecular self-assembly has been widely used to develop nanocarriers for drug delivery. However, most of them have unsatisfactory drug loading capacity (DLC) and the dilemma between stimuli-responsiveness and stability, stagnating their translational
Autor:
Matti Kankainen, Patrizia Stoitzner, Alberto Pessia, Lydia Bellmann, Akira Takeda, Beat A. Imhof, Sirpa Jalkanen, Dominik Eichin, Joni Laakkonen, Jing Tang, Marko Salmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2f396c33b77c3e9cde8c42bd1a5d6
https://doi.org/10.1002/eji.201948432/v3/response1
https://doi.org/10.1002/eji.201948432/v3/response1
Autor:
Jens Kuhle, Matthias Mehling, Stefanie Fritz, Christoph Hess, Patricia Hilbert, Raija L.P. Lindberg, Dominik Eichin, Bojana Durovic, Thomas Klimkait, Olivier Gasser, Ludwig Kappos
Publikováno v:
Annals of neurology
T cells exit secondary lymphoid organs along a sphingosine1-phosphate (S1P) gradient and, accordingly, are reduced in blood upon fingolimod-mediated S1P-receptor (S1PR)-blockade. Serving as a model of adaptive immunity, we characterized cellular and