Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Dominik Damm"'
Autor:
Jannik T. Wagner, Sandra M. Müller-Schmucker, Wenjun Wang, Philipp Arnold, Nadja Uhlig, Leila Issmail, Valentina Eberlein, Dominik Damm, Kaveh Roshanbinfar, Armin Ensser, Friederike Oltmanns, Antonia Sophia Peter, Vladimir Temchura, Silke Schrödel, Felix B. Engel, Christian Thirion, Thomas Grunwald, Manfred Wuhrer, Dirk Grimm, Klaus Überla
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Long-acting passive immunization strategies are needed to protect immunosuppressed vulnerable groups from infectious diseases. To further explore this concept for COVID-19, we constructed Adeno-associated viral (AAV) vectors encoding the hum
Externí odkaz:
https://doaj.org/article/fb0eb88696d04de18d534ac0c445bf7a
Autor:
Riccardo Di Vincenzo, Jannis Beutel, Philipp Arnold, Yu Wang, Dominik Damm, Pierre Tannig, Anja Lux, Vladimir Temchura, Jutta Eichler, Klaus Überla
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionConformationally stabilized Env trimers have been developed as antigens for the induction of neutralizing antibodies against HIV-1. However, the non-glycosylated immunodominant base of these soluble antigens may compete with the neutraliz
Externí odkaz:
https://doaj.org/article/2571239df4064bf6a4a340badd9701ae
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 24 (2023)
Infectious diseases are a predominant problem in human health. While the incidence of many pathogenic infections is controlled by vaccines, some pathogens still pose a challenging task for vaccine researchers. In order to face these challenges, the f
Externí odkaz:
https://doaj.org/article/50c000e4edd84f62831e78088731e1e1
Autor:
Claudia Gregoriano, Dominik Damm, Alexander Kutz, Daniel Koch, Selina Wolfisberg, Sebastian Haubitz, Anna Conen, Luca Bernasconi, Angelika Hammerer-Lercher, Christoph A. Fux, Beat Mueller, Philipp Schuetz
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) has been linked to thrombotic complications and endothelial dysfunction. We assessed the prognostic implications of endothelial activation through mea
Externí odkaz:
https://doaj.org/article/ccf3c61b07e04ce78b967eeb458246b2
Autor:
Dominik Damm, Ehsan Suleiman, Hannah Theobald, Jannik T. Wagner, Mirjam Batzoni, Bianca Ahlfeld (née Kohlhauser), Bernd Walkenfort, Jens-Christian Albrecht, Jidnyasa Ingale, Lifei Yang, Mike Hasenberg, Richard T. Wyatt, Karola Vorauer-Uhl, Klaus Überla, Vladimir Temchura
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1385 (2022)
Functionalization of experimental HIV-1 virus-like particle vaccines with heterologous T helper epitopes (T helper VLPs) can modulate the humoral immune response via intrastructural help (ISH). Current advances in the conjugation of native-like HIV-1
Externí odkaz:
https://doaj.org/article/d6bcf5265dc047d3a53880797af39283
Autor:
Pierre Tannig, Antonia Sophia Peter, Dennis Lapuente, Stephan Klessing, Anna Schmidt, Dominik Damm, Matthias Tenbusch, Klaus Überla, Vladimir Temchura
Publikováno v:
Vaccines, Vol 8, Iss 4, p 570 (2020)
Due to the low efficacy and the need for seasonal adaptation of currently licensed influenza A vaccines, the importance of alternative vaccination strategies is increasingly recognized. Considering that DNA vaccines can be rapidly manufactured and re
Externí odkaz:
https://doaj.org/article/80074c0243aa4d8b920c3d5c3b9515c0
Autor:
Pierre Tannig, Antonia Sophia Peter, Dennis Lapuente, Stephan Klessing, Dominik Damm, Matthias Tenbusch, Klaus Überla, Vladimir Temchura
Publikováno v:
Vaccines, Vol 8, Iss 1, p 27 (2020)
The importance of a balanced TH1/TH2 humoral immune response against the HIV-1 envelope protein (Env) for antibody-mediated HIV-1 control is increasingly recognized. However, there is no defined vaccination strategy to raise it. Since immune checkpoi
Externí odkaz:
https://doaj.org/article/b11748c22f39473c8006a055ee75f532
Autor:
Ehsan Suleiman, Dominik Damm, Mirjam Batzoni, Vladimir Temchura, Andreas Wagner, Klaus Überla, Karola Vorauer-Uhl
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 619 (2019)
Since the first use of liposomes as carriers for antigens, much work has been done to elucidate the mechanisms involved in the encapsulation of vaccine-relevant biomolecules. However, only a few studies have specifically investigated the encapsulatio
Externí odkaz:
https://doaj.org/article/51607de900f64ee6800d94a705cae2fa
Autor:
Dominik Damm, Leonardo Rojas-Sánchez, Hannah Theobald, Viktoriya Sokolova, Richard T. Wyatt, Klaus Überla, Matthias Epple, Vladimir Temchura
Publikováno v:
Nanomaterials, Vol 9, Iss 10, p 1389 (2019)
Incorporation of immunodominant T-helper epitopes of licensed vaccines into virus-like particles (VLP) allows to harness T-helper cells induced by the licensed vaccines to provide intrastructural help (ISH) for B-cell responses against the surface pr
Externí odkaz:
https://doaj.org/article/243f37476ac544929a1bd6054235b5b4
Publikováno v:
Pharmaceutics, Vol 11, Iss 5, p 204 (2019)
The great advantage of virus-like particle (VLP) nano-vaccines is their structural identity to wild-type viruses, ensuring that antigen-specific B-cells encounter viral proteins in their natural conformation. “Wild-type” viral nanoparticles can b
Externí odkaz:
https://doaj.org/article/5d4320ebd056409aae8cb09955fcd141