Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Dominik C. Kaczorowski"'
Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time
Autor:
Grace E. Lidgerwood, Anne Senabouth, Casey J.A. Smith-Anttila, Vikkitharan Gnanasambandapillai, Dominik C. Kaczorowski, Daniela Amann-Zalcenstein, Erica L. Fletcher, Shalin H. Naik, Alex W. Hewitt, Joseph E. Powell, Alice Pébay
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 223-242 (2021)
Human pluripotent stem cell (hPSC)-derived progenies are immature versions of cells, presenting a potential limitation to the accurate modelling of diseases associated with maturity or age. Hence, it is important to characterise how closely cells use
Externí odkaz:
https://doaj.org/article/a1b752ada11e4c119fcf167e7656b297
Autor:
Brian S. Gloss, Bethany Signal, Seth W. Cheetham, Franziska Gruhl, Dominik C. Kaczorowski, Andrew C. Perkins, Marcel E. Dinger
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Cellular responses to stimuli are rapid and continuous and yet the vast majority of investigations of transcriptional responses during developmental transitions typically use long interval time courses; limiting the available interpretive po
Externí odkaz:
https://doaj.org/article/b8a06b814e0248288830020045d527fd
Autor:
Dessislava Mladenova, Guy Barry, Lyndsey M. Konen, Sandy S. Pineda, Boris Guennewig, Lotta Avesson, Raphael Zinn, Nicole Schonrock, Maina Bitar, Nicky Jonkhout, Lauren Crumlish, Dominik C. Kaczorowski, Andrew Gong, Mark Pinese, Gloria R. Franco, Carl R. Walkley, Bryce Vissel, John S. Mattick
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The amount of regulatory RNA encoded in the genome and the extent of RNA editing by the post-transcriptional deamination of adenosine to inosine (A-I) have increased with developmental complexity and may be an important factor in the cognitive evolut
Externí odkaz:
https://doaj.org/article/035a01122d1e4d05b15faa12ae756e8d
Autor:
Walter Muskovic, Eve Slavich, Ben Maslen, Dominik C. Kaczorowski, Joseph Cursons, Edmund Crampin, Maria Kavallaris
Publikováno v:
Genome Research. 32:1463-1473
The advent of massively parallel sequencing revealed extensive transcription beyond protein-coding genes, identifying tens of thousands of long noncoding RNAs (lncRNAs). Selected functional examples raised the possibility that lncRNAs, as a class, ma
Autor:
Reginald V. Lord, Marcel E. Dinger, Melanie Edwards, Yuri V. Bobryshev, Antony Wettstein, David I. Watson, Damian J. Hussey, Melissa L. Thomas, Dominik C. Kaczorowski, Angelique Levert-Mignon, Oliver M. Fisher, Jesper L.V. Maag
Supplementary figure 2. Differentially expressed transcriptions factors between LGD and NDBE, and examples of EAC specific genes and eigen-modules from WGCNA. (a) Box plots of the top transcription factors (FOSB, FOSB, EGR1, EGR3, NR4A1, ATF3) differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078d365963d64f172a42c715fe12e5c2
https://doi.org/10.1158/1541-7786.22515652
https://doi.org/10.1158/1541-7786.22515652
Autor:
Reginald V. Lord, Marcel E. Dinger, Melanie Edwards, Yuri V. Bobryshev, Antony Wettstein, David I. Watson, Damian J. Hussey, Melissa L. Thomas, Dominik C. Kaczorowski, Angelique Levert-Mignon, Oliver M. Fisher, Jesper L.V. Maag
Esophageal adenocarcinoma (EAC) has one of the fastest increases in incidence of any cancer, along with poor five-year survival rates. Barrett's esophagus (BE) is the main risk factor for EAC; however, the mechanisms driving EAC development remain po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a3c8dc83f506b68399d0d06ede11cac
https://doi.org/10.1158/1541-7786.c.6541147
https://doi.org/10.1158/1541-7786.c.6541147
Autor:
Reginald V. Lord, Marcel E. Dinger, Melanie Edwards, Yuri V. Bobryshev, Antony Wettstein, David I. Watson, Damian J. Hussey, Melissa L. Thomas, Dominik C. Kaczorowski, Angelique Levert-Mignon, Oliver M. Fisher, Jesper L.V. Maag
Supplementary table 1 describes patient demographics and sample sequencing information Supplementary table 2 describes the top 20 differentially expressed genes, and the 12-gene signature. Supplementary table 3 shows the Discriminative performance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0660268e9c4bf1f072950459c23f4095
https://doi.org/10.1158/1541-7786.22515634.v1
https://doi.org/10.1158/1541-7786.22515634.v1
Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time
Autor:
Alice Pébay, Erica L. Fletcher, Daniela Amann-Zalcenstein, Shalin H. Naik, Anne Senabouth, Casey J.A. Smith-Anttila, Vikkitharan Gnanasambandapillai, Grace E. Lidgerwood, Dominik C. Kaczorowski, Joseph E. Powell, Alex W. Hewitt
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 223-242 (2021)
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics
Human pluripotent stem cell (hPSC)-derived progenies are immature versions of cells, presenting a potential limitation to the accurate modelling of disease associated with maturity or age. Hence, it is important to characterise how closely cells used
Autor:
Ramon Massoni-Badosa, Joseph E. Powell, Maria Salvany, Catia Moutinho, Carlota Rubio-Perez, Vanessa T. Chin, Joan Seoane, Eduard Batlle, Dominik C. Kaczorowski, Ester Planas-Rigol, Marc Elosua-Bayes, Chia-Ling Chan, Paula Nieto, Domenica Marchese, Josep M. Piulats, Ana Henriques, Ivo Gut, Richard Gallagher, Holger Heyn, Juan L. Trincado, Patricia Lorden, Juan C. Nieto, Elisabetta Mereu, Sara Ruiz, Angela Chou, Sergio Aguilar-Fernández
Publikováno v:
Genome Research
Dipòsit Digital de la UB
Universidad de Barcelona
Genome Res
Dipòsit Digital de la UB
Universidad de Barcelona
Genome Res
The tumor immune microenvironment is a main contributor to cancer progression and a promising therapeutic target for oncology. However, immune microenvironments vary profoundly between patients, and biomarkers for prognosis and treatment response lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c8407d0e6650bb7bd44e14fc1d9cc0
http://hdl.handle.net/2445/180737
http://hdl.handle.net/2445/180737
Autor:
Walter Muskovic, Joseph Cursons, Edmund J. Crampin, Eva Slavich, Dominik C. Kaczorowski, Maria Kavallaris, Ben Maslen
BackgroundThe advent of next-generation sequencing revealed extensive transcription beyond protein-coding genes, identifying tens of thousands of long non-coding RNAs (lncRNAs). Selected functional examples raised the possibility that lncRNAs, as a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97e4354130e183e913fb42fe1f528327
https://doi.org/10.1101/2021.08.25.457323
https://doi.org/10.1101/2021.08.25.457323