Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dominik Brokatzky"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT The metabolic island GEI4417/4436 of Salmonella enterica serovar Typhimurium (S. Typhimurium) enables the degradation of myo-inositol (MI) as the sole carbon and energy source. The island encodes two regulatory factors, the autoregulated rep
Externí odkaz:
https://doaj.org/article/0c78b602b3464bf68ea42160dd61b892
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 4, Pp 151359- (2023)
Staphylococcus aureus, a Gram-positive bacterial pathogen, is an urgent health threat causing a wide range of clinical infections. Originally viewed as a strict extracellular pathogen, accumulating evidence has revealed S. aureus to be a facultative
Externí odkaz:
https://doaj.org/article/2a4e19b813af4c758b710d43022eaf83
Autor:
Dominik Brokatzky, Serge Mostowy
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 7 (2022)
Pyroptosis, a regulated form of pro-inflammatory cell death, is characterised by cell lysis and by the release of cytokines, damage- and pathogen-associated molecular patterns. It plays an important role during bacterial infection, where it can promo
Externí odkaz:
https://doaj.org/article/ce41a254247c4692a8d4ca49fecb45c6
Autor:
Dominik Brokatzky, Georg Häcker
Publikováno v:
Medical Microbiology and Immunology. 211:161-172
Structure and integrity of the mitochondrial network play important roles in many cellular processes. Loss of integrity can lead to the activation of a variety of signalling pathways and affect the cell's response to infections. The activation of suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190edbe37bda63749cea46e7a14d6463
https://doi.org/10.1007/s00430-022-00742-9
https://doi.org/10.1007/s00430-022-00742-9
Autor:
Vincenzo Torraca, Magdalena K. Bielecka, Margarida C. Gomes, Dominik Brokatzky, Elisabeth M. Busch‐Nentwich, Serge Mostowy
Publikováno v:
Cytoskeleton.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c59b403eb7141c40f5e6f1c89e5752e
https://doi.org/10.1002/cm.21750
https://doi.org/10.1002/cm.21750
Autor:
Vincenzo Torraca, Dominik Brokatzky, Sydney L. Miles, Charlotte E. Chong, P. Malaka De Silva, Stephen Baker, Claire Jenkins, Kathryn E. Holt, Kate S. Baker, Serge Mostowy
SummaryShigellarepresents a paraphyletic group of human-adaptedEscherichia colilineages that converged towards the same enteropathogenic pathovar. In low-income countries,Shigellais typically transmitted by ingestion of contaminated water and food, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fa515f10977da102813bd08a83b1949
https://doi.org/10.1101/2022.11.08.515620
https://doi.org/10.1101/2022.11.08.515620
SUMMARYTrained immunity is a long-term memory of innate immune cells, generating an improved response upon re-infection.Shigellais an important human pathogen and inflammatory paradigm for which there is no effective vaccine. Using zebrafish larvae w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6feb805987bf5ab1af7d58deaffdef2
https://doi.org/10.1101/2022.11.03.515069
https://doi.org/10.1101/2022.11.03.515069
Autor:
Hoan Van Ngo, Stevens Robertin, Dominik Brokatzky, Magdalena K. Bielecka, Damián Lobato‐Márquez, Vincenzo Torraca, Serge Mostowy
Apoptosis is a form of regulated cell death essential for tissue homeostasis and embryonic development. Apoptosis also plays a key role during bacterial infection, yet some intracellular bacterial pathogens (such as Shigella flexneri, whose lipopolys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165636492c711f453e614a84b9f21c63
https://researchonline.lshtm.ac.uk/id/eprint/4666893/1/Ngo_etal_2022_Septins-promote-caspase-activity-and.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4666893/1/Ngo_etal_2022_Septins-promote-caspase-activity-and.pdf
Publikováno v:
Infect Immun
Apoptotic cell death can be an efficient defense reaction of mammalian cells infected with obligate intracellular pathogens; the host cell dies and the pathogen cannot replicate. While this is well established for viruses, there is little experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c471ba13bee43b7d42826bf5effb528d
https://doi.org/10.1128/iai.00851-19
https://doi.org/10.1128/iai.00851-19
Autor:
Julia Henschel, Dominik Brokatzky, Arnim Weber, Juliane Vier, Aladin Haimovici, Arlena Metz, Georg Häcker, Benedikt Dörflinger, Susanne Kirschnek, Tobias Steinfeldt, Ian E Gentle
Publikováno v:
EMBO J
Apoptosis is a frequent form of programmed cell death, but the apoptotic signaling pathway can also be engaged at a low level, in the absence of cell death. We here report that such sub-lethal engagement of mitochondrial apoptosis signaling causes th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc8d5e8e6dd8c5431fbde825ffef837
https://europepmc.org/articles/PMC6545560/
https://europepmc.org/articles/PMC6545560/