Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dominik Borrmann"'
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1897 (2022)
Anomalous water-sorption kinetics in amorphous solid dispersions (ASDs) are caused by the slow swelling of the polymer. In this work, we used a diffusion–relaxation model with the Williams–Landel–Ferry (WLF) equation and the Arrhenius equation
Externí odkaz:
https://doaj.org/article/8efe8b382d894692a0b9fd3587b34113
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1181 (2022)
Water decreases the stability of amorphous solid dispersions (ASDs) and water sorption is, therefore, unwanted during ASD storage. This work suggests a methodology to predict the water-sorption isotherms and the water-sorption kinetics in amorphous p
Externí odkaz:
https://doaj.org/article/0d545d9f73fd45dc820bde07e4460aa5
Publikováno v:
Membranes, Vol 12, Iss 4, p 434 (2022)
Polyvinylpyrrolidone (PVP)-based polymers are excellent stabilizers for food supplements and pharmaceutical ingredients. However, they are highly hygroscopic. This study measured and modeled the water-sorption isotherms and water-sorption kinetics in
Externí odkaz:
https://doaj.org/article/265132e3806d42c4bc1d61d459ee4a67
Publikováno v:
Molecular Pharmaceutics. 19:998-1007
The amorphous state of an active pharmaceutical ingredient (API) enhances its water solubility compared to its crystalline state. However, it is well known that amorphous substances can absorb significant amounts of water therewith inducing API recry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42692ffe8db9655a1dae60d7e978e643
https://doi.org/10.1021/acs.molpharmaceut.1c00984
https://doi.org/10.1021/acs.molpharmaceut.1c00984