Výsledky vyhledávání - "Dominik Böhme"

Differential reactivity of α and β 2′-deoxyribonucleosides towards protonation and metalation

Autor: Jens Müller, Nicole Düpre, Fabian-Alexander Polonius, Dominik Böhme, Michael Mehring

Publikováno v: Journal of Inorganic Biochemistry. 101:470-476

The reactivity of artificial 2'-deoxyribonucleosides, designed as nucleoside surrogates in metal-mediated base pairs, towards protonation and metalation has been shown to be dependent on the choice of the anomer. The alpha nucleosides comprising the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23e1cbcb1bf47ead28012be9e950628
https://doi.org/10.1016/j.jinorgbio.2006.11.011

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Solution structure of a DNA double helix with consecutive metal-mediated base pairs

Autor: Dominik Böhme, Nicole Megger, Jens Müller, Silke Johannsen, Roland K. O. Sigel

Publikováno v: Nature chemistry. 2(3)

Metal-mediated base pairs represent a powerful tool for the site-specific functionalization of nucleic acids with metal ions. The development of applications of the metal-modified nucleic acids will depend on the availability of structural informatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5cffe406a0f02522017b37b2a90260
https://pubmed.ncbi.nlm.nih.gov/21124482

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Conformational change induced by metal-ion-binding to DNA containing the artificial 1,2,4-triazole nucleoside

Autor: Dominik A. Megger, Jens Müller, Dominik Böhme, Nicole Düpre

Publikováno v: Inorganic chemistry. 46(24)

A conformational switch can be induced upon the addition of transition-metal ions to oligonucleotides that contain a row of successive artificial nucleobases flanked by complementary sequences of natural nucleobases, provided that the artificial base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b82a604339c61a0101c69ce9dda20a
https://pubmed.ncbi.nlm.nih.gov/17973476

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Metal ion coordination to azole nucleosides

Autor: Jens Müller, Dominik Böhme, Marta Morell Cerdà, Michael Roitzsch, Patrick Lax

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 11(21)

To evaluate the possibility of introducing azole nucleosides as building blocks for metal-mediated base pairs in artificial oligonucleotides, imidazole nucleoside, 1,2,4-triazole nucleoside and tetrazole nucleoside have been synthesized and character

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b50afdfc6f3f7dd32bc5586d2ff0a3
https://pubmed.ncbi.nlm.nih.gov/16075445

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