Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Dominik A. Barth"'
Autor:
Dominik A. Barth, Stefanie Stanzer, Jasmin Spiegelberg, Thomas Bauernhofer, Gudrun Absenger, Florian Posch, Rainer Lipp, Michael Halm, Joanna Szkandera, Marija Balic, Armin Gerger, Maria A. Smolle, Georg C. Hutterer, Christiane Klec, Philipp J. Jost, Julia Kargl, Martin Stradner, Martin Pichler
Publikováno v:
Cancer Medicine, Vol 11, Iss 16, Pp 3074-3083 (2022)
Abstract Background The presence of autoantibodies in the serum of cancer patients has been associated with immune‐checkpoint inhibitor (ICI) therapy response and immune‐related adverse events (irAEs). A prospective evaluation of different autoan
Externí odkaz:
https://doaj.org/article/8914eb1a50484886b516dc8999f59708
Autor:
Renate Pichler, Peter J. Siska, Piotr Tymoszuk, Agnieszka Martowicz, Gerold Untergasser, Roman Mayr, Florian Weber, Andreas Seeber, Florian Kocher, Dominik A. Barth, Martin Pichler, Martin Thurnher
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Renal cell carcinoma (RCC) is frequently infiltrated by immune cells, a process which is governed by chemokines. CD8+ T cells in the RCC tumor microenvironment (TME) may be exhausted which most likely influence therapy response and survival. The aim
Externí odkaz:
https://doaj.org/article/26dd55bbbaf4450489ea940ca2cd59b3
Autor:
Andrea Katharina Lindner, Martin Pichler, Sarah Maier, Hanno Ulmer, Thomas Gorreri, Anna Katharina Luger, Dominik A. Barth, Andreas Seeber, Florian Kocher, Renate Pichler
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Upper tract urothelial carcinoma (UTUC) is an aggressive disease that is managed by radical or organ-sparing surgery. High recurrence rates require early detection and strict follow-up (FU) protocols. Recommendations are assigned to a low level of ev
Externí odkaz:
https://doaj.org/article/7eb421c2f13f4f63b81fb69143fb53e1
Autor:
Hannah Fluhrer, Georg C. Hutterer, Sylvia Golbeck, Michael Stidl, Tobias Niedrist, Renate Pichler, Johannes Mischinger, Maximilian Seles, Sebastian Mannweiler, Jasmin Spiegelberg, Thomas Bauernhofer, Philipp J. Jost, Sascha Ahyai, Richard Zigeuner, Martin Pichler, Dominik A. Barth
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: The treatment landscape of metastatic renal cell carcinoma (mRCC) has substantially advanced over the last three decades, whereby data from controlled clinical trials indicate significant improvements regarding patients’ overall surviva
Externí odkaz:
https://doaj.org/article/1ad8615ac9ab434590e72d3eae997bc7
Autor:
Dominik A. Barth, Stefanie Stanzer, Jasmin A. Spiegelberg, Thomas Bauernhofer, Gudrun Absenger, Joanna Szkandera, Armin Gerger, Maria A. Smolle, Georg C. Hutterer, Sascha A. Ahyai, Tobias Madl, Florian Posch, Jakob M. Riedl, Christiane Klec, Philipp J. Jost, Julia Kargl, Martin H. Stradner, Martin Pichler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundImmune checkpoint inhibitors (ICIs) have revolutionized systemic anti-tumor treatments across different types of cancer. Nevertheless, predictive biomarkers regarding treatment response are not routinely established yet. Apart from T-lympho
Externí odkaz:
https://doaj.org/article/1c7e71b457324a089d3b19334f744c70
Autor:
Mohammad Taheri, Dominik A. Barth, Julia Kargl, Omidvar Rezaei, Soudeh Ghafouri-Fard, Martin Pichler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T-lymphocytes (T cells) play a major role in adaptive immunity and current immune checkpoint inhibitor-based cancer treatments. The regulation of their function is complex, and in addition to cytokines, receptors and transcription factors, several no
Externí odkaz:
https://doaj.org/article/31713c80918a4bdc9d96b2bb322438e8
Autor:
Dominik A. Barth, Rares Drula, Leonie Ott, Linda Fabris, Ondrej Slaby, George A. Calin, Martin Pichler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Liquid biopsy—the determination of circulating cells, proteins, DNA or RNA from biofluids through a “less invasive” approach—has emerged as a novel approach in all cancer entities. Circulating non-(protein) coding RNAs including microRNAs (mi
Externí odkaz:
https://doaj.org/article/0a78656daac14bf08e48b1b93d15cf11
Autor:
Florian Posch, Felix Prinz, Amar Balihodzic, Christian Mayr, Tobias Kiesslich, Christiane Klec, Katharina Jonas, Dominik A. Barth, Jakob M. Riedl, Armin Gerger, Martin Pichler
Publikováno v:
Cancers, Vol 13, Iss 16, p 3996 (2021)
Biliary tract cancer is a major global health issue in cancer-related mortality. Therapeutic options are limited, and cisplatin-based treatment schedules represent the mainstay of first-line therapeutic strategies. Although the gain of survival by th
Externí odkaz:
https://doaj.org/article/3bcaa709e5d644aaae244edb2c9d3df9
Publikováno v:
Cancers, Vol 13, Iss 5, p 977 (2021)
The rapid and uncontrolled proliferation of cancer cells is supported by metabolic reprogramming. Altered glucose metabolism supports cancer growth and progression. Compared with normal cells, cancer cells show increased glucose uptake, aerobic glyco
Externí odkaz:
https://doaj.org/article/3fb96b18e10146ceb63b9d217b19b412
Publikováno v:
Viruses, Vol 12, Iss 12, p 1374 (2020)
The emergence of SARS-CoV-2 in 2019 has caused a major health and economic crisis around the globe. Gaining knowledge about its attributes and interactions with human host cells is crucial. Non-coding RNAs (ncRNAs) are involved in the host cells’ i
Externí odkaz:
https://doaj.org/article/f7fae8fc48214d99b4cd975acb0b461e