Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dominik, Heimann"'
Autor:
Timo Risch, Dominik Kolling, Dietrich Mostert, Tim Seedorf, Dominik Heimann, Daniel Kohnhäuser, Felix Deschner, Franziska Fries, Danny Solga, Jil-Sophie Hilgers, Jan Dastbaz, Stefano Mancini, Anna K. H. Hirsch, Mark Brönstrup, Andreas Kirschning, Stephan A. Sieber, Jennifer Herrmann, Rolf Müller
Publikováno v:
npj Antimicrobials and Resistance, Vol 2, Iss 1, Pp 1-12 (2024)
Abstract Antimicrobial resistance is one of the major health threats of the modern world. Thus, new structural classes of antimicrobial compounds are needed in order to overcome existing resistance. Cystobactamids represent one such new compound clas
Externí odkaz:
https://doaj.org/article/d82bddf7ab0144049f713a0e4128ea79
Autor:
Lars Pache, Matthew D. Marsden, Peter Teriete, Alex J. Portillo, Dominik Heimann, Jocelyn T. Kim, Mohamed S.A. Soliman, Melanie Dimapasoc, Camille Carmona, Maria Celeridad, Adam M. Spivak, Vicente Planelles, Nicholas D.P. Cosford, Jerome A. Zack, Sumit K. Chanda
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100037- (2020)
Summary: “Shock and kill” strategies focus on purging the latent HIV-1 reservoir by treating infected individuals with therapeutics that activate the latent virus and subsequently eliminating infected cells. We have previously reported that induc
Externí odkaz:
https://doaj.org/article/844b2284d4654ae7b526e217e79fb151
Autor:
Mathias Winterhalter, Rolf Müller, Janetta Coetzee, Bettina Hinkelmann, Nanaji Arisetti, Mark Brönstrup, Jennifer Herrmann, Dominik Ruppelt, Manuel Orozco, Claudia Steinem, Eric Kuhnert, Jayesh Arun Bafna, Satya Prathyusha Bhamidimarri, Hazel Leanne Sarah Fuchs, Stephan A. Sieber, Dominik Heimann, Konstantin Eckel, Armin Bauer, Peter Müller
Publikováno v:
Chemical Science
Emerging antimicrobial resistance urges the discovery of antibiotics with unexplored, resistance-breaking mechanisms. Armeniaspirols represent a novel class of antibiotics with a unique spiro[4.4]non-8-ene scaffold and potent activities against Gram-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43c603fab2dd0efcf45747e86c9e3df
https://pubmed.ncbi.nlm.nih.gov/35024125
https://pubmed.ncbi.nlm.nih.gov/35024125
Autor:
Peter Teriete, Matthew D. Marsden, Jerome A. Zack, Vicente Planelles, Camille Carmona, Sumit K. Chanda, Dominik Heimann, Adam M. Spivak, Maria Celeridad, Nicholas D. P. Cosford, Lars Pache, Jocelyn T. Kim, Mohamed S.A. Soliman, Alex J. Portillo, Melanie Dimapasoc
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100037-(2020)
Cell Reports Medicine
Cell Reports Medicine
Summary “Shock and kill” strategies focus on purging the latent HIV-1 reservoir by treating infected individuals with therapeutics that activate the latent virus and subsequently eliminating infected cells. We have previously reported that induct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e625a17d3aebe525d17d95aacb59e75
http://www.sciencedirect.com/science/article/pii/S2666379120300495
http://www.sciencedirect.com/science/article/pii/S2666379120300495
Autor:
Darren Finlay, Nicole Bata, Dominik Heimann, Nicholas D. P. Cosford, Allison S. Limpert, Carol Burian, Kristiina Vuori, Peter Teriete, James R. Mason
Publikováno v:
Cancer Research. 80:2405-2405
Acute myeloid leukemia (AML) is a diverse collection of hematological cancers characterized by the bone marrow's excessive production of certain immature myeloid blood cells. The American Cancer Society estimated that there was ~11,000 deaths and ~21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607b25fdef6ed57645f2dbe0a36e44eb
https://doi.org/10.1158/1538-7445.am2020-2405
https://doi.org/10.1158/1538-7445.am2020-2405
Autor:
Dominik, Heimann, Frederik, Börgel, Henk, de Vries, Marius, Patberg, Eliot, Jan-Smith, Bastian, Frehland, Dirk, Schepmann, Laura H, Heitman, Bernhard, Wünsch
Publikováno v:
European journal of medicinal chemistry. 146
The central CB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f686465e8b0286f1682d569d80ee8a5
https://pubmed.ncbi.nlm.nih.gov/29407967
https://pubmed.ncbi.nlm.nih.gov/29407967
Autor:
Frederik Börgel, Bastian Frehland, Victoria E. Rose, Dominik Heimann, Henk de Vries, Bernhard Wünsch, Dirk Schepmann, Kim Bachmann, Laura H. Heitman
Publikováno v:
European Journal of Medicinal Chemistry, 143, 1436-1447. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry
Recently, the development of the fluorinated PET tracer [F-18]1a for imaging of CB2 receptors in the central nervous system was reported. [F-18]1a showed high CB2 affinity and selectivity over the CB1 subtype, but rapid biotransformation in mice. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77cf029a89664768305df66687a66c4
https://doi.org/10.1016/j.ejmech.2017.10.049
https://doi.org/10.1016/j.ejmech.2017.10.049
Autor:
Dirk Schepmann, Corinna Lueg, Bastian Frehland, Dominik Heimann, Laura H. Heitman, Henk de Vries, Bernhard Wünsch
Publikováno v:
MedChemComm, 8, 1697-1705. ROYAL SOC CHEMISTRY
It has been reported that bioisosteric replacement of an 1,2,4-oxadiazole ring by an 1,3,4-oxadiazole ring leads to higher polarity, reduced metabolic degradation by human liver microsomes and reduced interaction with hERG channels. In a seven to eig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cc16e8923391992e6dfa097faa4af3
https://doi.org/10.1039/c7md00296c
https://doi.org/10.1039/c7md00296c