Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dominick Matteau"'
Autor:
Antoine Champie, Jean-Christophe Lachance, Anand Sastry, Dominick Matteau, Colton J. Lloyd, Frédéric Grenier, Cameron R. Lamoureux, Simon Jeanneau, Adam M. Feist, Pierre-Étienne Jacques, Bernhard O. Palsson, Sébastien Rodrigue
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Microorganisms with simplified genomes represent interesting cell chassis for systems and synthetic biology. However, genome reduction can lead to undesired traits, such as decreased growth rate and metabolic imbalances. To investigate the i
Externí odkaz:
https://doaj.org/article/04a55e0de4eb4ac2a7d3e89e6f0be8fb
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Mesoplasma florum is an emerging model organism for systems and synthetic biology due to its small genome (∼800 kb) and fast growth rate. While M. florum was isolated and first described almost 40 years ago, many important aspects of its biology ha
Externí odkaz:
https://doaj.org/article/87985913c305490887cdc29348570f00
Autor:
Jean‐Christophe Lachance, Dominick Matteau, Joëlle Brodeur, Colton J Lloyd, Nathan Mih, Zachary A King, Thomas F Knight, Adam M Feist, Jonathan M Monk, Bernhard O Palsson, Pierre‐Étienne Jacques, Sébastien Rodrigue
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 7, Pp 1-20 (2021)
Abstract Mesoplasma florum, a fast‐growing near‐minimal organism, is a compelling model to explore rational genome designs. Using sequence and structural homology, the set of metabolic functions its genome encodes was identified, allowing the rec
Externí odkaz:
https://doaj.org/article/ffd50eb1a2234bef84adfb826296e9f3
Autor:
Dominick Matteau, Sébastien Rodrigue
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 10, Pp 1-3 (2021)
Abstract Bacterial infections are commonly treated with antimicrobials, but the rise of multi‐drug resistance and the presence of biofilms can compromise treatment efficacy. Recently, new approaches using live bacteria or engineered microorganisms
Externí odkaz:
https://doaj.org/article/c39d1954526f40a2b45ffde2547167a4
Autor:
Dominick Matteau, Jean‐Christophe Lachance, Frédéric Grenier, Samuel Gauthier, James M Daubenspeck, Kevin Dybvig, Daniel Garneau, Thomas F Knight, Pierre‐Étienne Jacques, Sébastien Rodrigue
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp 1-25 (2020)
Abstract The near‐minimal bacterium Mesoplasma florum is an interesting model for synthetic genomics and systems biology due to its small genome (~ 800 kb), fast growth rate, and lack of pathogenic potential. However, fundamental aspects of its bio
Externí odkaz:
https://doaj.org/article/3774f6c6b32544339ba24881ef15941d
Autor:
Marc Larochelle, Marc-Antoine Robert, Jean-Nicolas Hébert, Xiaochuan Liu, Dominick Matteau, Sébastien Rodrigue, Bin Tian, Pierre-Étienne Jacques, François Bachand
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA
Externí odkaz:
https://doaj.org/article/1de494ea30714a22bec8e626430ecc54
Inferring the Minimal Genome of Mesoplasma florum by Comparative Genomics and Transposon Mutagenesis
Autor:
Vincent Baby, Jean-Christophe Lachance, Jules Gagnon, Jean-François Lucier, Dominick Matteau, Tom Knight, Sébastien Rodrigue
Publikováno v:
mSystems, Vol 3, Iss 3 (2018)
ABSTRACT The creation and comparison of minimal genomes will help better define the most fundamental mechanisms supporting life. Mesoplasma florum is a near-minimal, fast-growing, nonpathogenic bacterium potentially amenable to genome reduction effor
Externí odkaz:
https://doaj.org/article/1a7fae27dd8140b8b773108b4a75ec92
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133384 (2015)
Continuous culture devices can be used for various purposes such as establishing reproducible growth conditions or maintaining cell populations under a constant environment for long periods. However, commercially available instruments are expensive,
Externí odkaz:
https://doaj.org/article/50259fb7761349b98d709e11ef5af9a0
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004714 (2014)
Dissemination of antibiotic resistance genes occurs mostly by conjugation, which mediates DNA transfer between cells in direct contact. Conjugative plasmids of the IncA/C incompatibility group have become a substantial threat due to their broad host-
Externí odkaz:
https://doaj.org/article/72ec8445a2ab45508898034b933f7734
Autor:
Sébastien Rodrigue, Bernhard O. Palsson, Dominick Matteau, Jean-Christophe Lachance, Joëlle Brodeur, Adam M. Feist, Zachary A. King, Thomas F. Knight, Colton J. Lloyd, Nathan Mih, Jonathan M. Monk, Pierre-Étienne Jacques
Publikováno v:
Lachance, JC, Matteau, D, Brodeur, J, Lloyd, C J, Mih, N, King, Z A, Knight, T F, Feist, A M, Monk, J M, Palsson, B O, Jacques, PÉ & Rodrigue, S 2021, ' Genome-scale metabolic modeling reveals key features of a minimal gene set ', Molecular Systems Biology, vol. 17, no. 7, e10099 . https://doi.org/10.15252/msb.202010099
Molecular Systems Biology
Molecular Systems Biology, Vol 17, Iss 7, Pp n/a-n/a (2021)
Molecular Systems Biology
Molecular Systems Biology, Vol 17, Iss 7, Pp n/a-n/a (2021)
Mesoplasma florum, a fast‐growing near‐minimal organism, is a compelling model to explore rational genome designs. Using sequence and structural homology, the set of metabolic functions its genome encodes was identified, allowing the reconstructi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efe59c4f39bd5f147ed48a859da769d
https://orbit.dtu.dk/en/publications/6c5fb099-d5ce-4372-8b47-e669ebfea949
https://orbit.dtu.dk/en/publications/6c5fb099-d5ce-4372-8b47-e669ebfea949
