Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dominick G A Burton"'
Autor:
Dominick G A Burton, Maria G Giribaldi, Anisleidys Munoz, Katherine Halvorsen, Asmita Patel, Merce Jorda, Carlos Perez-Stable, Priyamvada Rai
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68003 (2013)
Androgen deprivation (AD) is an effective method for initially suppressing prostate cancer (PC) progression. However, androgen-refractory PC cells inevitably emerge from the androgen-responsive tumor, leading to incurable disease. Recent studies have
Externí odkaz:
https://doaj.org/article/e8c108d649c24e299fff0ac2f2a92555
Publikováno v:
Nutrition Bulletin. 43:442-455
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf138f3498d33a6c343a1d55a19e927
https://doi.org/10.1111/nbu.12356
https://doi.org/10.1111/nbu.12356
Publikováno v:
Biogerontology
Cellular senescence is now considered as a major mechanism in the development and progression of various diseases and this may include metabolic diseases such as obesity and type-2 diabetes. The presence of obesity and diabetes is a major risk factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ee9830946b3d5f91807eaa6b874772
http://europepmc.org/articles/PMC6223730
http://europepmc.org/articles/PMC6223730
Publikováno v:
Ageing Research Reviews. 43:17-25
In response to persistent DNA damage, induction into cell senescence promotes an immunogenic program which facilitates immune clearance of these damaged cells. Under physiological conditions, senescent cells can activate both innate and adaptive immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958a6b607a5ea9732540dc1c40d070d4
https://doi.org/10.1016/j.arr.2018.02.001
https://doi.org/10.1016/j.arr.2018.02.001
Publikováno v:
Biogerontology
Lipids are essential for physiological processes such as maintaining membrane integrity, providing a source of energy and acting as signalling molecules to control processes including cell proliferation, metabolism, inflammation and apoptosis. Disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dc92e5386e1d12469d9c8aa77a7522
http://europepmc.org/articles/PMC5684309
http://europepmc.org/articles/PMC5684309
Autor:
Hilah Gal, Georg Mahlknecht, Luigi Mazzeo, Julian Downward, Tomer-Meir Salame, Yehoshua Enuka, Donatella Romaniello, Moshit Lindzen, Dominick G. A. Burton, Maicol Mancini, Emilie Bousquet, Dan Adreka, Raya Eilam Altstadter, Nadège Gaborit, Antonio Maraver, Ashish Noronha, Valery Krizhanovsky, Yosef Yarden, Ilaria Marrocco, Lee Roth
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 2, Pp 294-308 (2018)
EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2018, 10 (2), pp.294-308. ⟨10.15252/emmm.201708076⟩
EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2018, 10 (2), pp.294-308. ⟨10.15252/emmm.201708076⟩
International audience; Epidermal growth factor receptor (EGFR) mutations identify patients with lung cancer who derive benefit from kinase inhibitors. However, most patients eventually develop resistance, primarily due to the T790M second-site mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d56fdf41271807f767a95c82f34c456
https://hdl.handle.net/10807/227168
https://hdl.handle.net/10807/227168
Publikováno v:
Cellular and Molecular Life Sciences
Cellular senescence, a permanent state of cell cycle arrest accompanied by a complex phenotype, is an essential mechanism that limits tumorigenesis and tissue damage. In physiological conditions, senescent cells can be removed by the immune system, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5487b2a8b99939ef7e1cf1cb54808e
https://doi.org/10.1007/s00018-014-1691-3
https://doi.org/10.1007/s00018-014-1691-3
Autor:
Carlos Perez-Stable, Asmita Patel, Alexander Cohen, Wayne Balkan, Priyamvada Rai, Maria G. Giribaldi, Samer Singh, Dominick G. A. Burton, Dao M. Nguyen, David J. Robbins, Anisleidys Munoz, Teresita Reiner, Katherine Halvorsen
Publikováno v:
Oncogene
Oncogenic RAS promotes production of reactive oxygen species (ROS), which mediate pro-malignant signaling but can also trigger DNA damage-induced tumor suppression. Thus RAS-driven tumor cells require redox-protective mechanisms to mitigate the damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bf63d447b718ad4854955f56c95e69
https://doi.org/10.1038/onc.2014.195
https://doi.org/10.1038/onc.2014.195
Autor:
Valery Krizhanovsky, Ezra Vadai, Felix M. Wensveen, Bojan Polić, Adi Sagiv, Zhana Moshayev, Ofra Golani, Dominick G. A. Burton, Shifra Ben-Dor
Publikováno v:
Aging
Volume 8
Issue 2
Aging (Albany NY)
ResearcherID
Europe PubMed Central
Scopus-Elsevier
Volume 8
Issue 2
Aging (Albany NY)
ResearcherID
Europe PubMed Central
Scopus-Elsevier
Cellular senescence is a stress response mechanism that limits tumorigenesis and tissue damage. Induction of cellular senescence commonly coincides with an immunogenic phenotype that promotes self-elimination by components of the immune system, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f4cf4f15e3b21ba4a3cacc2f0d788e
https://repository.medri.uniri.hr/islandora/object/medri:3142/datastream/FILE0
https://repository.medri.uniri.hr/islandora/object/medri:3142/datastream/FILE0
Autor:
Dominick G. A. Burton
Publikováno v:
AGE. 31:1-9
Cellular senescence is the irreversible growth arrest of individual mitotic cells, which as a consequence display a radically altered phenotype that is thought to impair tissue function and predispose tissues to disease development and/or progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d3f4778eac73cf23779f8275468bf7
https://doi.org/10.1007/s11357-008-9075-y
https://doi.org/10.1007/s11357-008-9075-y