Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dominic van Essen"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nucleosome organisation plays important roles in regulating functional genomic elements. Here, the authors use high-resolution profiling to analyse dynamic nucleosome positioning at inducible and cell-type-specific promoters, providing a global view
Externí odkaz:
https://doaj.org/article/45f1d464110d44cca74836c93ff1fa30
Autor:
Indre Piragyte, Thomas Clapes, Aikaterini Polyzou, Ramon I. Klein Geltink, Stylianos Lefkopoulos, Na Yin, Pierre Cauchy, Jonathan D. Curtis, Lhéanna Klaeylé, Xavier Langa, Cora C. A. Beckmann, Marcin W. Wlodarski, Patrick Müller, Dominic Van Essen, Angelika Rambold, Friedrich G. Kapp, Marina Mione, Joerg M. Buescher, Erika L. Pearce, Alexander Polyzos, Eirini Trompouki
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
HLX transcription factor regulates haematopoietic stem and progenitor cell (HSPC) differentiation and is overexpressed in acute myeloid leukemia. Here the authors show that HLX overexpression leads to myeloid differentiation block in zebrafish and hu
Externí odkaz:
https://doaj.org/article/6e1870de09fa401dacacea3d50a2697e
Publikováno v:
PLoS Biology, Vol 16, Iss 5, p e2004526 (2018)
Gene expression in eukaryotes is controlled by DNA sequences at promoter and enhancer regions, whose accessibility for binding by regulatory proteins dictates their specific patterns of activity. Here, we identify the protein Zbtb7a as a factor requi
Externí odkaz:
https://doaj.org/article/ffaf8ac271ed4b99b59617a76da1835a
Autor:
Claude Philippe, Dulce B Vargas-Landin, Aurélien J Doucet, Dominic van Essen, Jorge Vera-Otarola, Monika Kuciak, Antoine Corbin, Pilvi Nigumann, Gaël Cristofari
Publikováno v:
eLife, Vol 5 (2016)
LINE-1 (L1) retrotransposons represent approximately one sixth of the human genome, but only the human-specific L1HS-Ta subfamily acts as an endogenous mutagen in modern humans, reshaping both somatic and germline genomes. Due to their high levels of
Externí odkaz:
https://doaj.org/article/2156c4975491454aadddfbb79fa34777
Publikováno v:
PLoS Biology, Vol 7, Iss 3, p e73 (2009)
The NF-kappaB family of transcription factors is crucial for the expression of multiple genes involved in cell survival, proliferation, differentiation, and inflammation. The molecular basis by which NF-kappaB activates endogenous promoters is largel
Externí odkaz:
https://doaj.org/article/535483075c684f21a674ff0a8cbf0ccc
Autor:
Saadat Hussain, Nori Sadouni, Dominic van Essen, Lan T M Dao, Quentin Ferré, Guillaume Charbonnier, Magali Torres, Frederic Gallardo, Charles-Henri Lecellier, Tom Sexton, Simona Saccani, Salvatore Spicuglia
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2023, 51 (10), pp.4845-4866. ⟨10.1093/nar/gkad187⟩
Nucleic Acids Research, 2023, 51 (10), pp.4845-4866. ⟨10.1093/nar/gkad187⟩
The action of cis-regulatory elements with either activation or repression functions underpins the precise regulation of gene expression during normal development and cell differentiation. Gene activation by the combined activities of promoters and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f251cd5a4a94c26385ec4ca6a5de3b35
https://cnrs.hal.science/hal-04044391
https://cnrs.hal.science/hal-04044391
Autor:
Sophie Lanciano, Claude Philippe, Arpita Sarkar, David Pratella, Cécilia Domrane, Aurélien J. Doucet, Dominic van Essen, Simona Saccani, Laure Ferry, Pierre-Antoine Defossez, Gael Cristofari
GRAPHICAL ABSTRACTHIGHLIGHTSAggregate analysis masks the heterogeneity of L1 DNA methylationThe region immediately adjacent to an L1 insertion frequently adopts the L1 methylation stateL1-associated epivariation is accompanied by differential transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf1b33ffbdfb94960ad0838196338a10
https://doi.org/10.1101/2023.01.03.522582
https://doi.org/10.1101/2023.01.03.522582
Autor:
Bogdan B. Grigorash, Dominic van Essen, Laurent Grosse, Alexander Emelyanov, Benoît Kanzler, Clement Molina, Elsa Lopez, Oleg N. Demidov, Carmen Garrido, Simona Saccani, Dmitry V. Bulavin
The discovery of four factor (4F)-induced reprogramming of somatic cells into induced pluripotent stem (iPS) cells has revolutionized the fields of cell and regenerative biology. In contrast, the feasibility of a direct conversion of somatic cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a92fa15dbfa34b16dd596d83bbe471a
https://doi.org/10.1101/2022.08.24.504108
https://doi.org/10.1101/2022.08.24.504108
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2351
The positioning of nucleosomes regulates the accessibility of genomic DNA and can impact the activities of functional elements. Nucleosome positioning is highly consistent at each genomic location in any particular cell-type, but can vary in an orche
Publikováno v:
Methods in Molecular Biology ISBN: 9781071615966
The positioning of nucleosomes regulates the accessibility of genomic DNA and can impact the activities of functional elements. Nucleosome positioning is highly consistent at each genomic location in any particular cell-type, but can vary in an orche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::707cdb3aae4ca4aa0876bb93fec46621
https://doi.org/10.1007/978-1-0716-1597-3_7
https://doi.org/10.1007/978-1-0716-1597-3_7