Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dominic Santoleri"'
Autor:
Kahealani Uehara, Jaimarie Sostre-Colón, Matthew Gavin, Dominic Santoleri, Kelly-Ann Leonard, René L. Jacobs, Paul M. Titchenell
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 6, Pp 1625-1647 (2022)
Background & Aims: Dysregulation of liver lipid metabolism is associated with the development and progression of nonalcoholic fatty liver disease, a spectrum of liver diseases including nonalcoholic steatohepatitis (NASH). In the liver, insulin contr
Externí odkaz:
https://doaj.org/article/517ca050c381446883e15db8cf510b15
Autor:
Dominic Santoleri, Hee-Woong Lim, Matthew J. Emmett, Julian Stoute, Matthew J. Gavin, Jaimarie Sostre-Colón, Kahealani Uehara, Jaclyn E. Welles, Kathy Fange Liu, Mitchell A. Lazar, Paul M. Titchenell
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104410- (2022)
Summary: The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting an
Externí odkaz:
https://doaj.org/article/7c71e331dbf74cd59745668fc81b8721
Autor:
Dominic Santoleri, Paul M. Titchenell
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 447-456 (2019)
Insulin resistance is associated with numerous metabolic disorders, such as obesity and type II diabetes, that currently plague our society. Although insulin normally promotes anabolic metabolism in the liver by increasing glucose consumption and lip
Externí odkaz:
https://doaj.org/article/24b21863371a401892908c66b00bb666
Publikováno v:
Endocrinology
The hepatic transcription factor forkhead box O1 (FOXO1) is a critical regulator of hepatic and systemic insulin sensitivity. Previous work by our group and others demonstrated that genetic inhibition of FOXO1 improves insulin sensitivity both in gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe30bc435e46307634e904f969f199e
https://doi.org/10.1210/endocr/bqac035
https://doi.org/10.1210/endocr/bqac035
Autor:
Dominic, Santoleri, Hee-Woong, Lim, Matthew J, Emmett, Julian, Stoute, Matthew J, Gavin, Jaimarie, Sostre-Colón, Kahealani, Uehara, Jaclyn E, Welles, Kathy Fange, Liu, Mitchell A, Lazar, Paul M, Titchenell
Publikováno v:
iScience. 25(6)
The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting and refeedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce773bade043e87e6634adbcac4f4525
https://pubmed.ncbi.nlm.nih.gov/35663017
https://pubmed.ncbi.nlm.nih.gov/35663017
Autor:
Paul M. Titchenell, Dominic Santoleri
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Insulin resistance is associated with numerous metabolic disorders, such as obesity and type II diabetes, that currently plague our society. Although insulin normally promotes anabolic metabolism in the liver by increasing glucose consumption and lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27eb16d2a993c3fec511936ebd4c8dd
https://doi.org/10.1016/j.jcmgh.2018.10.016
https://doi.org/10.1016/j.jcmgh.2018.10.016
Publikováno v:
ChemBioChem. 21:281-281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c99b7c82a3545b88bd65dd3b71c7908a
https://doi.org/10.1002/cbic.202000013
https://doi.org/10.1002/cbic.202000013
Publikováno v:
Volume 14, Issue 3. 14
The formation of blood clots is vital for biological repair of injured blood vessels. When a blood vessel is injured, platelets come into contact with collagen, causing glycoprotein VI (GPVI) to undergo a conformational change and initialize the clot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1863f473e1b14d1d5a6cd1f06d0d6937
https://doi.org/10.33697/ajur.2017.026
https://doi.org/10.33697/ajur.2017.026