Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Dominic R. Saiz"'
Autor:
Constantine N. Tzouanas, Maria M. Mihaylova, Peter Carmeliet, Shinya Imada, Dorukhan Bahceci, Anna T. Webb, Amanda M. Hussey, Ömer H. Yilmaz, Yesenia Barrera Millan, Alex K. Shalek, Miyeko D. Mana, Caroline A. Lewis, Dominic R. Saiz
Publikováno v:
Cell reports
Elsevier
Mana, M D, Hussey, A M, Tzouanas, C N, Imada, S, Barrera Millan, Y, Bahceci, D, Saiz, D R, Webb, A T, Lewis, C A, Carmeliet, P, Mihaylova, M M, Shalek, A K & Yilmaz, Ö H 2021, ' High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity ', Cell Reports, vol. 35, no. 10, 109212 . https://doi.org/10.1016/j.celrep.2021.109212
CELL REPORTS
Elsevier
Mana, M D, Hussey, A M, Tzouanas, C N, Imada, S, Barrera Millan, Y, Bahceci, D, Saiz, D R, Webb, A T, Lewis, C A, Carmeliet, P, Mihaylova, M M, Shalek, A K & Yilmaz, Ö H 2021, ' High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity ', Cell Reports, vol. 35, no. 10, 109212 . https://doi.org/10.1016/j.celrep.2021.109212
CELL REPORTS
SUMMARY Obesity is an established risk factor for cancer in many tissues. In the mammalian intestine, a pro-obesity high-fat diet (HFD) promotes regeneration and tumorigenesis by enhancing intestinal stem cell (ISC) numbers, proliferation, and functi