Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Dominic Picarella"'
Autor:
Branden Moriarity, Marilyn Marques, Vipin Suri, Bashar Hamza, Angela Nunez, Henry Moreno, Alexia Barandiaran, Evelyn Warren, Cristina Panaroni, Michele McAuliffe, Krista Daniel, Julianne Murthy, Keith HK Wong, Mark Omobono, Priya Khurana, Beatriz Marques, Adriana Rivera, Jae Woong Chang, Joseph Gold, Cherry Thomas, Dominic Picarella
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f735c5dd6f6149f5b0827c3e10c3efe5
Autor:
Finola Moore, Andres Alvarez, Alexia Barandiaran, Luke Barron, Eugene Choi, Krista Daniel, Charlotte Franco, Bashar Hamza, Jennifer Johnson, Annie Khamhoung, Marilyn Marques, Henry Moreno, Angela Nunez, Dominic Picarella Jared Sewell, Alex Storer, Meghan Walsh, Vipin Suri
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Celeste Richardson, Finola Moore, Andres Alvarez, Alexia Barandiaran, Luke Barron, Eugene Choi, Tucker Ezell, Charlotte Franco, Bashar Hamza, Jennifer Johnson, Annie Khamhoung, Taeyoon Kyung, Marilyn Marques, Dominic Picarella, Jared Sewell, Alex Storer, Meghan Walsh, Vipin Suri
Publikováno v:
Cancer Research. 82:555-555
Despite the success of HER2 targeted therapies in HER2+ breast and gastric cancer, additional therapies are needed to address treatment-resistant metastatic disease. Adoptive immune cell therapy is a promising therapeutic modality given the remarkabl
Autor:
Chi B. Vu, Min Ding, Ericka L. Benson, Robert Kleemann, Martine C. Morrison, Rick B. Vega, Diana Y. Lee, Maisy Yeager, Michael R. Jirousek, Andrew J. Nichols, Guosheng Liang, Teake Kooistra, Michael Zimmer, Jill C. Milne, Dominic Picarella, Peter Y. Wielinga, Feng Liu, Jay D. Horton, Pradeep Bista
Publikováno v:
Hepatology Communications
CAT-2003 is a novel conjugate of eicosapentaenoic acid (EPA) and niacin designed to be hydrolyzed by fatty acid amide hydrolase to release EPA inside cells at the endoplasmic reticulum. In cultured liver cells, CAT-2003 blocked the maturation of ster
Autor:
Amal Ting, Abby Sewell, Cecilia Pena-Rasgado, Dominic Picarella, Antonio E. Lacerda, Maisy Yeager, Chi B. Vu, Chandran Sachin, Pallavi Lonkar, Robert J. Bridges, A. Nichols, Curtis Bordwell, Feng Liu, Allison Wensley
Publikováno v:
Journal of medicinal chemistry. 60(1)
A depressed autophagy has previously been reported in cystic fibrosis patients with the common F508del-CFTR mutation. This report describes the synthesis and preliminary biological characterization of a novel series of autophagy activators involving
Autor:
Andrew J. Nichols, Pallavi Lonkar, Jean Bemis, Michael R. Jirousek, Michael Zimmer, Diana Lee, Jill C. Milne, Adam Shoelson, Amal Ting, Dominic Picarella, Maisy Yeager, Ericka L. Benson, Feng Liu, Smith Jesse J, David Carney, Allison Wensley, Chi B. Vu, Richard Fahrner, P. Bista
Publikováno v:
Journal of medicinal chemistry. 59(3)
This report describes the synthesis and preliminary biological characterization of novel fatty acid niacin conjugates and fatty acid salicylate conjugates. These molecular entities were created by covalently linking two bioactive molecules, either ni
Autor:
Mike Briskin, Bengt Johansson-Lindbom, Marcus Svensson, Hanna Stenstad, Dominic Picarella, William W. Agace, Anna Ericsson, Dulce Soler, Matthias Mack, Gabriel Márquez, Jan Marsal
Publikováno v:
Blood. 107:3447-3454
CD4(+) T-cell entry to the intestinal mucosa is central to the generation of mucosal immunity as well as chronic intestinal inflammation, yet the mechanisms regulating this process remain poorly defined. Here we show that murine small intestinal CD4(
Autor:
Dominic Picarella, Marion Dorsch, Bruce Jaffee, Lisa Schopf, Michael Fitzgerald, Nancy Paz, Tao Wang, Aileen Healy, Michelle Dupont, Karen Anderson, Tim Ocain, Yajun Xu
Publikováno v:
Autoimmunity. 39:469-478
In the present study we have characterized T cell-driven immune function in mice that are genetically deficient in PKC theta. In response to simple immunologic stimulation invoked by in vivo T cell receptor (TCR) cross-linking, these mice showed sign
Autor:
Michael Zimmer, A. Nichols, Dominic Picarella, Arlin Rogers, Diana Lee, Joanne M. Donovan, Michael Briggs
Publikováno v:
Journal of Clinical Lipidology. 10:722-723
Autor:
Thomas Kamradt, Alberto Sanchez-Fueyo, Vijay K. Kuchroo, Orissa Bender, Jane Tian, Jose-Carlos Gutierrez-Ramos, Terry B. Strom, Dominic Picarella, Catherine A. Sabatos, Natasha Manlongat, Anthony J. Coyle, Christoph Domenig, Xin Xiao Zheng
Publikováno v:
Nature Immunology. 4:1093-1101
Although T helper (T(H)) cell-mediated immunity is required to effectively eliminate pathogens, unrestrained T(H) activity also contributes to tissue injury in many inflammatory and autoimmune diseases. We report here that the T(H) type 1 (T(H)1)-spe