Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dominic P, Bryne"'
Autor:
Bjoern Meyer, Jeanne Chiaravalli, Stacy Gellenoncourt, Philip Brownridge, Dominic P. Bryne, Leonard A. Daly, Arturas Grauslys, Marius Walter, Fabrice Agou, Lisa A. Chakrabarti, Charles S. Craik, Claire E. Eyers, Patrick A. Eyers, Yann Gambin, Andrew R. Jones, Emma Sierecki, Eric Verdin, Marco Vignuzzi, Edward Emmott
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
During SARS-CoV-2 replication, viral and cellular proteases play crucial roles and have been shown to be promising anti-viral targets. Here, Meyer et al. apply mass spectrometry to characterize the proteolytic cleavage profile of viral and cellular p
Externí odkaz:
https://doaj.org/article/09cd9fa5dad54609b514710cffa2869d
Autor:
Jeanne Chiaravalli, Marius Walter, Edward Emmott, Emma Sierecki, Stacy Gellenoncourt, Philip Brownridge, Arturas Grauslys, Andrew R. Jones, Fabrice Agou, Charles S. Craik, Marco Vignuzzi, Yann Gambin, Patrick A. Eyers, Lisa A. Chakrabarti, Eric Verdin, Leonard A. Daly, Bjoern Meyer, Dominic P. Bryne, Claire E. Eyers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications, 2021, 12 (1), pp.5553. ⟨10.1038/s41467-021-25796-w⟩
Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, 2021, 12 (1), pp.5553. ⟨10.1038/s41467-021-25796-w⟩
Nature communications, vol 12, iss 1
SARS-CoV-2 is the causative agent behind the COVID-19 pandemic, responsible for over 170 million infections, and over 3.7 million deaths worldwide. Efforts to test, treat and vaccinate against this pathogen all benefit from an improved understanding
Autor:
Claire E. Eyers, Patrick A. Eyers, Giancarlo Barone, Karl Patterson, J. Mark Skehel, Abhijit A. Patil, Spencer J. Collis, Katie N. Myers, Sarah L. Maslen, Anil Ganesh, Dominic P. Bryne, Christopher J. Staples
Publikováno v:
Nucleic Acids Research
Cyclin-dependent kinases (CDKs) coordinate cell cycle checkpoints with DNA repair mechanisms that together maintain genome stability. However, the myriad mechanisms that can give rise to genome instability are still to be fully elucidated. Here, we i
Autor:
Guillaume, Combes, Helena, Barysz, Chantal, Garand, Luciano, Gama Braga, Ibrahim, Alharbi, Philippe, Thebault, Luc, Murakami, Dominic P, Bryne, Stasa, Stankovic, Patrick A, Eyers, Victor M, Bolanos-Garcia, William C, Earnshaw, John, Maciejowski, Prasad V, Jallepalli, Sabine, Elowe
Publikováno v:
Current Biology
Summary Monopolar spindle 1 (Mps1) is a conserved apical kinase in the spindle assembly checkpoint (SAC) that ensures accurate segregation of chromosomes during mitosis. Mps1 undergoes extensive auto- and transphosphorylation, but the regulatory and