Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Dominic Keating"'
Autor:
Brenda M. Button, Lisa M. Wilson, Angela T. Burge, Lara Kimmel, Felicity Finlayson, Elyssa Williams, Anthony Talbot, Audrey Tierney, Susannah King, Anne E. Holland, Dominic Keating, Tom Kotsimbos, John W. Wilson
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Background Quality of life has improved dramatically over the past two decades in people with cystic fibrosis (CF). Quantification has been enabled by patient-reported outcome measures (PROMs); however, many are lengthy and can be challenging to use
Externí odkaz:
https://doaj.org/article/7495dec67b6c492ea6f1457ab438d7c9
Autor:
Susannah J. King, Dominic Keating, Elyssa Williams, Eldho Paul, Brigitte M. Borg, Felicity Finlayson, Brenda M. Button, John W. Wilson, Tom Kotsimbos
Publikováno v:
ERJ Open Research, Vol 7, Iss 1 (2021)
Introduction Lumacaftor/ivacaftor (LUM/IVA) has been shown to improve clinical outcomes in cystic fibrosis (CF) patients homozygous for Phe508del with forced expiratory volume in 1 s (FEV1) % pred >40%. We assessed the clinical utility of LUM/IVA in
Externí odkaz:
https://doaj.org/article/7098879b20a2481d8007c4747cebd423
Autor:
Samantha Ellis, Catherine Rang, Tom Kotsimbos, Dominic Keating, Felicity Finlayson, Richard Stark, Dominic Thyagarajan, John Wilson
Publikováno v:
BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)
Background Acute neurological events may present as an extrapulmonary complication in patients with cystic fibrosis (CF). These events can be secondary to a range of different aetiologies.Methods A retrospective analysis of 476 medical records of CF
Externí odkaz:
https://doaj.org/article/7fb8fe822fac4b88abb06a7af48d8eea
Publikováno v:
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, Vol 12 (2018)
Background and objective: Over 2000 genotypes in the cystic fibrosis (CF) gene have been described. These genotypic differences result in variable clinical manifestations of CF, with severity of disease dependent on CF transmembrane conductance (CFTR
Externí odkaz:
https://doaj.org/article/098b0547120e440bb80efe1249a20b1d
Autor:
Judy Allen-Graham, Elyssa Williams, Catherine Rang, Brenda Button, Deirdre Edgeworth, Felicity Finlayson, Toby Winton-Brown, Tom Kotsimbos, Dominic Keating, John Wilson
Publikováno v:
Psychological Disorders and Research. :1-6
Background: Cystic fibrosis is not typically associated with cognitive dysfunction that is easily discernible. Whether having a CFTR mutation has a direct effect on the CNS function is yet to be elucidated, despite widespread expression of the CFTR p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b8371b117cc9593800716bd8434919b
https://doi.org/10.31487/j.pdr.2022.01.01
https://doi.org/10.31487/j.pdr.2022.01.01
Autor:
Dominic Keating, Krita Sridharan
Publikováno v:
Internal medicine journal. 52(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246c6ad9393d1d77909023b752befaf1
https://pubmed.ncbi.nlm.nih.gov/36404118
https://pubmed.ncbi.nlm.nih.gov/36404118
Autor:
Dominic Keating, P. Steele, Nathan Dwyer, Trevor Williams, Melanie Lavender, David S. Celermajer, John Feenstra, Susanna Proudman, Benjamin Ng, Mark Horrigan, Robert G. Weintraub, Vivek Thakkar, Eugene Kotlyar, Geoff Strange, James Anderson, Nicholas Collins, Jeremy P. Wrobel, Helen Whitford, Anne Keogh, Edmund M.T. Lau
Publikováno v:
Heart, Lung and Circulation. 29:1459-1468
Combination drug therapy for pulmonary arterial hypertension (PAH) is the international standard of care for most patients, however in Australia there are barriers to drug access. This study evaluates current treatment of PAH patients in Australia an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3a24d8e65acd602ceab4e0403a7a1d
https://doi.org/10.1016/j.hlc.2020.01.017
https://doi.org/10.1016/j.hlc.2020.01.017
Autor:
Anne Keogh, Carolyn Corrigan, Eugene Kotlyar, James Anderson, Jeremy P. Wrobel, Trevor Williams, Nicholas Collins, Nathan Dwyer, Dominic Keating, Robert G. Weintraub, Helen Whitford, David S. Celermajer, P. Steele, Victor Khou, John Feenstra, Ken Whyte, Melanie Lavender, Tanya McWilliams, Mark Horrigan, Edmund M.T. Lau, Geoff Strange
Publikováno v:
Respirology. 25:863-871
Background and objective Early diagnosis of PAH is clinically challenging. Patterns of diagnostic delay in Australian and New Zealand PAH populations have not been explored in large-scale studies. We aimed to evaluate the magnitude, risk factors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10de4e10d5376e39fd99f35fcb70e10b
https://doi.org/10.1111/resp.13768
https://doi.org/10.1111/resp.13768
Autor:
Dominic Keating, E Kotlyar, Edmund M.T. Lau, Nathan Dwyer, Rachael Cordina, K. Kearney, Melanie Lavender, Trevor Williams, David S. Celermajer, R. Weintraub, Anne Keogh, Helen Whitford, K. Whyte, James Anderson, Nicholas Collins
Publikováno v:
European Heart Journal. 42
Background Contemporary registries have documented a change in the epidemiology of PAH patients displaying increasing co-morbidities associated with left heart disease (LHD). These patients are often excluded from randomized clinical trials. It is un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04532c90ff92299b25794d123b16d3ad
https://doi.org/10.1093/eurheartj/ehab724.1958
https://doi.org/10.1093/eurheartj/ehab724.1958
Autor:
Warren Clements, Georgina Venn, David McGiffin, Heather K. Moriarty, Tim Joseph, Gerard S. Goh, Helen Whitford, Dominic Keating
Publikováno v:
Respiratory medicine. 195
In many patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH), bronchial artery hypertrophy is observed. Patients with bronchial dilatation have been shown to be at increased risk of hemoptysis introducing the risk of airway obstruction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a717736ac2533ec210fdc643fa84fd29
https://pubmed.ncbi.nlm.nih.gov/35232634
https://pubmed.ncbi.nlm.nih.gov/35232634