Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Dominic J. Autelitano"'
Publikováno v:
International Dairy Journal. 20:480-486
A novel, highly enriched bioactive bovine whey protein fraction (LAP001) was shown to directly inhibit adipocyte differentiation and lipid accumulation over a wide concentration range. Further in vitro characterisation showed that LAP001 suppressed i
Autor:
Edgell Tracey A, Philip S. Rudland, Gregory E. Rice, Roger Barraclough, Janu Dhulia, Dominic J. Autelitano, Antonio Rajic, Dong Liu Barraclough, Kate J. Lewis, Jane E. Armes
Publikováno v:
Clinical Science. 118:717-725
Ovarian cancer is often asymptomatic and is diagnosed at an advanced stage with poor survival rates, thus there is an urgent need to develop biomarkers for earlier detection of ovarian cancer. In the present study, we demonstrate for the first time t
Autor:
Peter Grant, Gillian Barker, Dominic J. Autelitano, David W. Allen, Gregory E. Rice, G. Martin-Roussety, Edgell Tracey A
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose The primary hypothesis to be tested in this study was that the diagnostic performance (as assessed by the area under the receiver operator characteristic curve, AUC) of a multianalyte panel to correctly identify women with ovarian cancer was
Autor:
Antonio Rajic, Christiane Stehmann, Gregory E. Rice, Christopher G. Hosking, Ana K. Vrkic, Dominic J. Autelitano, Leodevico L. Ilag
Publikováno v:
Preparative Biochemistry and Biotechnology. 39:221-247
Given that proteomic analysis of complex protein mixtures may be restricted by the presence of highly abundant proteins, sample preparation to remove abundant proteins is essential for the analysis of low abundance proteins. Chickens are effective pr
Publikováno v:
Cardiovascular Research. 70:555-565
Objective Mineralocorticoids and glucocorticoids have been implicated in the pathogenesis of cardiac diseases; however, both in vivo and in vitro studies indicate that changes in the cellular milieu of either the cardiomyocyte and/or cells of the vas
Autor:
Elodie Percy, Alex Agrotis, Garry L. Jennings, Elizabeth A. Woodcock, Xiao-Jun Du, Xiao-Ming Gao, Anthony M. Dart, Dominic J. Autelitano
Publikováno v:
Endocrinology. 144:4097-4105
Sex differences in cardiomyopathic phenotype and the role of gonadal status were studied in mice with cardiac overexpression of beta(2)-adrenergic receptors (ARs) over 6-15 months (mo) of age. Survival to 15 mo was 96% in wild-type mice but was poore
Autor:
Walter G. Thomas, Ross D. Hannan, Darren J. Kelly, Alex Tzanidis, Henry Krum, Done Onan, Dominic J. Autelitano, Fiona See, Richard E. Gilbert
Publikováno v:
Circulation Research. 93:246-253
Urotensin II (UII) is a somatostatin-like peptide recently identified as a potent vasoconstrictor. In this study, we examined whether UII promotes cardiac remodeling through nonhemodynamic effects on the myocardium. In a rat model of heart failure af
Autor:
Xiao-Jun Du, Ross D. Hannan, Xiao-Ming Gao, Yves Brandenburger, Jane F. Arthur, Dominic J. Autelitano, Elizabeth A. Woodcock, Lawrence I. Rothblum
Publikováno v:
FEBS Letters. 548:79-84
The ribosomal DNA transcription-specific factor, UBF, is a key target for the regulation of ribosomal RNA synthesis and hypertrophic growth of isolated neonatal cardiomyocytes. In this study, we have examined whether UBF expression is also an importa
Publikováno v:
Biology of Reproduction. 68:2005-2012
Adrenomedullin (AM) has been found in the brain as well as in various peripheral tissues, including reproductive organs such as the testis and the prostate. Here, we report the expression of AM in the rat epididymis and its role in anion secretion. W
Autor:
Rebecca Ridings, Dominic J. Autelitano
Publikováno v:
Peptides. 22:1851-1857
Adrenomedullin (AM) is a multifunctional peptide with a range of cardiovascular functions including direct effects on cardiomyocytes. Despite the demonstration of high numbers of AM binding sites in rat heart, the receptor responsible for cardiac AM