Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dominic G. Spinella"'
Publikováno v:
BioTechniques, Vol 26, Iss 2, Pp 208-214 (1999)
Externí odkaz:
https://doaj.org/article/8e5ca3edebf64d4b8dfa93e0c4cde373
Publikováno v:
Current Medical Research and Opinion. 29:517-525
To assess the impact of a serum-based proteomic test for non-small-cell lung cancer (NSCLC) on physician treatment recommendations.A multivariate, serum-based proteomic test (VeriStrat) is commercially available to assist physicians when determining
Autor:
Dominic G Spinella
Publikováno v:
Biomarkers in Medicine. 3:667-669
as well as the extremely high attrition rates. This has led to a need for objective end points that allow a clinical trial sponsor to quickly evaluate whether or not an experimental drug is at least ‘reasonably likely’ to produce the requisite cl
Autor:
Gary Chappell, Alexandra K. Bernardino, Patricia Koutz, Stephen J. McConnell, Steven Gerken, Dominic G. Spinella, Yalin Wei, Kristi K. Myers, Amy C. Redding, Ellen K. Pratt
Publikováno v:
Nucleic Acids Research. 27:i-viii
We have developed a new and simple method for quantitatively analyzing global gene expression profiles from cells or tissues. The process, called TALEST, or tandem arrayed ligation of expressed sequence tags, employs an oligonucleotide adapter contai
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 2:155-163
Abstract: A fusion protein construct consisting of the short form of human fibroblast growth factor (FGFR) fused to the heavy c;hain of mouse lgG1 was used to screen four phage display libraries displaying 8, 13, 38 and 43 amino acids at the amino te
Autor:
Stephen J. McConnell, Steven Joel Brown, Alice Whalley, Curtis Kautzer, Huong Le, Kirsten Blumeyer, Kathleen Ann Becherer, Dominic G. Spinella, Fumiko Axelrod
Publikováno v:
Protein Expression and Purification. 14:120-124
We have developed a cloning vector for the expression of type I cytokine receptor, NO, extracellular domain (ECD)-mouse IgG1 Fc fusion proteins. The vector has a versatile polylinker that allows in-frame cloning of the receptor ECD with the mouse IgG
Publikováno v:
Molecular Diversity. 1:165-176
We have constructed two phage display libraries expressing N-terminal pIII fusions in M13 composed of 37 and 43 random amino acid domains, respectively. The D38 library expresses 37 random amino acids with a central alanine residue, and the DC43 libr
Publikováno v:
Immunogenetics. 34:23-27
Collagen-induced arthritis (CIA) is a rodent arthritis model in which immunization with heterologous type II collagen induces an inflammatory polyarthritis. Susceptibility to the disease is mediated by major histocompatibility complex (MHC) genes as
Autor:
Jerome M. Seyer, Dominic G. Spinella, James P. Thompson, Min-Chi Huang, Kathy S. E. Cheah, Andrew H. Kang
Publikováno v:
European Journal of Biochemistry. 195:593-600
The nucleotide sequence of the human procollagen alpha 1(II) collagen gene extending from within the first intron through exon 15, and part of the 15th intron has been determined. This sequence analysis (7056 bases) identifies the intron/exon organiz