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pro vyhledávání: '"Dominic G. Hoch"'
Autor:
Roman Lagoutte, Christelle Serba, Daniel Abegg, Dominic G. Hoch, Alexander Adibekian, Nicolas Winssinger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Deoxyelephantopin is a naturally occurring sesquiterpene lactone with known anticancer properties. Here, the authors synthesize deoxyelephantopins and a range of analogues including alkyne-tagged probes, using them to identify its cellular targets.
Externí odkaz:
https://doaj.org/article/1ed6d7b632384db6874986b87650499b
Publikováno v:
CHIMIA, Vol 70, Iss 11 (2016)
Our laboratory focuses on chemical proteomics-enabled discovery of new cysteine-reactive small molecules with intriguing biomedical activities as well as identification and detailed characterization of their proteomic targets. In this overview articl
Externí odkaz:
https://doaj.org/article/889198009fc6470689130cce87e0862e