Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dominic F. Cairns-Gibson"'
Publikováno v:
Cairns-Gibson, D & Cockroft, S L 2021, ' Functionalised Nanopores: Chemical and Biological Modifications ', Chemical Science . https://doi.org/10.1039/D1SC05766A
Nanopore technology has established itself as a powerful tool for single-molecule studies. By analysing changes in the ion current flowing through a single transmembrane channel, a wealth of molecular information can be elucidated. Early studies util
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e7d2ab8de154f8d746f44c6da3ee5a
https://pubmed.ncbi.nlm.nih.gov/35308845
https://pubmed.ncbi.nlm.nih.gov/35308845
Publikováno v:
Haugland, M, Borsley, S, Cairns-Gibson, D, Elmi, A & Cockroft, S 2019, ' Synthetically Diversified Protein Nanopores: Resolving Click Reaction Mechanisms ', ACS Nano . https://doi.org/10.1021/acsnano.8b08691
Nanopores are emerging as a powerful tool for the investigation of nanoscale processes at the single-molecule level. Here, we demonstrate the methionine-selective synthetic diversification of α-hemolysin (α-HL) protein nanopores and their exploitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ec3d45dc95fc197a3cbf9e39e45fb3
https://doi.org/10.1021/acsnano.8b08691
https://doi.org/10.1021/acsnano.8b08691
Autor:
Stefan Borsley, Iñigo J. Vitorica-Yrezabal, Marios Leonidou, Jonathan Clayden, Anna D. Peters, Simon J. Webb, Eriko Takano, John Burthem, George F. S. Whitehead, Dominic F. Cairns-Gibson, Scott L. Cockroft, Flavio della Sala
Publikováno v:
Peters, A D, Borsley, S, della Sala, F, Cairns-Gibson, D, Leonidou, M, Clayden, J, Whitehead, G, Vitórica-Yrezábal, I, Takano, E, Burthem, J, Cockroft, S L & Webb, S J 2020, ' Switchable foldamer ion channels with antibacterial activity ', Chemical Science . https://doi.org/10.1039/D0SC02393K
Chemical Science
Peters, A D, Borsley, S, Della Sala, F, Cairns-Gibson, D F, Leonidou, M, Clayden, J, Whitehead, G F S, Vitórica-Yrezábal, I J, Takano, E, Burthem, J, Cockroft, S L & Webb, S J 2020, ' Switchable foldamer ion channels with antibacterial activity ', Chemical Science, vol. 11, no. 27, pp. 7023-7030 . https://doi.org/10.1039/D0SC02393K
Peters, A D, Borsley, S, Della Sala, F, Cairns-gibson, D F, Leonidou, M, Clayden, J, Whitehead, G F S, Vitorica-yrzebal, I, Takano, E, Burthem, J, Cockroft, S L & Webb, S 2020, ' Switchable foldamer ion channels with antibacterial activity ', Chemical Science . https://doi.org/10.1039/D0SC02393K
Chemical Science
Peters, A D, Borsley, S, Della Sala, F, Cairns-Gibson, D F, Leonidou, M, Clayden, J, Whitehead, G F S, Vitórica-Yrezábal, I J, Takano, E, Burthem, J, Cockroft, S L & Webb, S J 2020, ' Switchable foldamer ion channels with antibacterial activity ', Chemical Science, vol. 11, no. 27, pp. 7023-7030 . https://doi.org/10.1039/D0SC02393K
Peters, A D, Borsley, S, Della Sala, F, Cairns-gibson, D F, Leonidou, M, Clayden, J, Whitehead, G F S, Vitorica-yrzebal, I, Takano, E, Burthem, J, Cockroft, S L & Webb, S 2020, ' Switchable foldamer ion channels with antibacterial activity ', Chemical Science . https://doi.org/10.1039/D0SC02393K
Triazole-capped α-aminoisobutyric acid (Aib) octameric foldamers formed very active ion channels in phospholipid bilayers after the addition of copper(ii) chloride, with activity “turned off” by copper(ii) extraction.
Synthetic ion channels
Synthetic ion channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8f2da1d65de5e795ac0acacda8fd9b
https://www.pure.ed.ac.uk/ws/files/154160083/20200701_Cockroft_Switchable_d0sc02393k.pdf
https://www.pure.ed.ac.uk/ws/files/154160083/20200701_Cockroft_Switchable_d0sc02393k.pdf
Autor:
Jessica L. Rouge, Dominic F. Cairns-Gibson, Mark Q. Tolentino, Halle M. Barber, Joshua J. Santiana, Alyssa K. Hartmann
Publikováno v:
ChemBioChem. 19:1734-1739
Herein, we describe the characterization of a novel self-assembling and intracellular disassembling nanomaterial for nucleic acid delivery and targeted gene knockdown. By using a recently developed nucleic acid nanocapsule (NAN) formed from surfactan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac2b4d400b8d4300418349e35605520
https://doi.org/10.1002/cbic.201800302
https://doi.org/10.1002/cbic.201800302
Autor:
Joseph K. Awino, Joshua J. Santiana, Saketh Gudipati, Alyssa K. Hartmann, Dominic F. Cairns-Gibson, Jessica L. Rouge, Nicole Gomez
Publikováno v:
Journal of the American Chemical Society. 139:6278-6281
Herein we describe a nucleic acid functionalized nanocapsule in which nucleic acid ligands are assembled and disassembled in the presence of enzymes. The particles are fully degradable in response to esterases due to an embedded ester cross-linker in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ed0b6faff949ad9a596a1d39f32067
https://doi.org/10.1021/jacs.6b13087
https://doi.org/10.1021/jacs.6b13087
Autor:
Dominic F. Cairns-Gibson, Jessica L. Rouge, Halle M. Barber, Mark Q. Tolentino, Alyssa K. Hartmann, Joshua J. Santiana
Publikováno v:
ChemBioChem. 19:1664-1664
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72571a346a7222c033e5f48e87c65fb2
https://doi.org/10.1002/cbic.201800401
https://doi.org/10.1002/cbic.201800401