Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dominic F, Qualley"'
Autor:
Michael B. Morgan, Jacob Williams, Barrett Breeze, Nicholas English, Nathaniel Higdon, Kirt Onthank, Dominic F. Qualley
Publikováno v:
Frontiers in Physiology, Vol 14 (2024)
Cnidarians face significant threats from ocean acidification (OA) and anthropogenic pollutants such as oxybenzone (BP-3). The convergence of threats from multiple stressors is an important area to investigate because of potential significant synergis
Externí odkaz:
https://doaj.org/article/74cb454c071b48beb94eab5cbf73b7d8
A series of eleven 5-substituted-indole nucleoside residues were synthesized and incorporated into 15-mer oligodeoxynucleotide duplexes with each of the four natural bases (A, G, C, T) paired with the non-natural residues. The universal base properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08691a36114790f744ba2e49233288da
Autor:
Sarah Cooper, Erik D. Olson, Dominic F. Qualley, William A. Cantara, James Ross, Karin Musier-Forsyth
Bovine leukemia virus (BLV) is a deltaretrovirus that infects domestic cattle. The structural protein Gag, found in all retroviruses, is a polyprotein comprising three major functional domains: matrix (MA), capsid (CA), and nucleocapsid (NC). Previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e16366977d8718125e7e89ee9a0f71
https://europepmc.org/articles/PMC6424597/
https://europepmc.org/articles/PMC6424597/
Autor:
Hao Wu, Karin Musier-Forsyth, Robert J. Gorelick, Ioulia Rouzina, Wei Wang, Dominic F. Qualley, Eric J. Fichtenbaum, Mark C. Williams, Nada Naiyer, Micah J. McCauley
Publikováno v:
Virus Research. 193:39-51
Feline immunodeficiency virus (FIV) is a retrovirus that infects domestic cats, and is an excellent animal model for human immunodeficiency virus type 1 (HIV-1) pathogenesis. The nucleocapsid (NC) protein is critical for replication in both retroviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffca068423ab7a22e950dcda6b1291c1
https://doi.org/10.1016/j.virusres.2014.06.002
https://doi.org/10.1016/j.virusres.2014.06.002
Autor:
Karin Musier-Forsyth, Kathy R. Chaurasiya, Mark C. Williams, Wei Wang, Tiyun Wu, Amber Hertz, Dominic F. Qualley, Shingo Kitamura, Ioulia Rouzina, Denise S.B. Chan, Hylkje Geertsema, Judith G. Levin, Yasumasa Iwatani, Micah J. McCauley
Publikováno v:
Nature chemistry
The human APOBEC3 proteins are a family of DNA-editing enzymes that play an important role in the innate immune response and have broad activity against retroviruses and retrotransposons. APOBEC3G is a member of this family that inhibits HIV-1 replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa51f5e42e286939cb7dca31dc924604
http://europepmc.org/articles/PMC3950479
http://europepmc.org/articles/PMC3950479
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 81:1377-1385
The matrix (MA) domain of retroviral Gag proteins plays a crucial role in virion assembly. In human immunodeficiency virus type 1 (HIV-1), a lentivirus, the presence of phosphatidylinositol-(4,5)-bisphosphate triggers a conformational change allowing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af60cf6be2a6afb1692c0c10a6d44ba4
https://doi.org/10.1002/prot.24281
https://doi.org/10.1002/prot.24281
Autor:
Ioulia Rouzina, Kristen M. Stewart-Maynard, Dominic F. Qualley, Robert J. Gorelick, Fei Wang, Mithun Mitra, Mark C. Williams, Karin Musier-Forsyth
Publikováno v:
Journal of Biological Chemistry. 285:295-307
Retroviral nucleocapsid (NC) proteins are molecular chaperones that facilitate nucleic acid (NA) remodeling events critical in viral replication processes such as reverse transcription. Surprisingly, the NC protein from human T-cell leukemia virus ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2a381340179054cce958ac9af516ca
https://doi.org/10.1074/jbc.m109.051334
https://doi.org/10.1074/jbc.m109.051334
Publikováno v:
Tetrahedron Letters. 48:8074-8077
Polycyclic aromatic hydrocarbons were found to be promising universal bases in PNA·DNA double helices. Several of the arenes paired promiscuously with any of the four canonical bases. However, the stabilities of the duplexes depended on the size and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91016da99d88a7052498876013d7ad50
https://doi.org/10.1016/j.tetlet.2007.09.019
https://doi.org/10.1016/j.tetlet.2007.09.019
Publikováno v:
Biochemical and biophysical research communications. 458(3)
Nucleocapsid proteins (NCs) direct the rearrangement of nucleic acids to form the most thermodynamically stable structure, and facilitate many steps throughout the life cycle of retroviruses. NCs bind strongly to nucleic acids (NAs) and promote NA ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a242ca7792281dcfaea8155ae39ad692
https://pubmed.ncbi.nlm.nih.gov/25686502
https://pubmed.ncbi.nlm.nih.gov/25686502
Publikováno v:
Protein expression and purification. 93
In retroviruses, the Gag protein is a precursor from which the mature proteins matrix, capsid, and nucleocapsid are derived. Gag plays an important structural role in the assembly of virions at the plasma membrane. While Gag proteins from several dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc31f934ab0afd929daccb2c5a9e2dd2
https://pubmed.ncbi.nlm.nih.gov/24161562
https://pubmed.ncbi.nlm.nih.gov/24161562