Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dominic E Fullenkamp"'
Autor:
Dominic E. Fullenkamp, Alexander B. Willis, Jodi L. Curtin, Ansel P. Amaral, Kyle T. Dittloff, Sloane I. Harris, Ivana A. Chychula, Cory W. Holgren, Paul W. Burridge, Brenda Russell, Alexis R. Demonbreun, Elizabeth M. McNally
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/b52a5eadd7514af8ba2316e6c7190c6b
Autor:
Dominic E Fullenkamp, Alexander B Willis, Jodi L Curtin, Ansel P Amaral, Sloane I Harris, Paul W Burridge, Alexis R Demonbreun, Elizabeth M McNally
Publikováno v:
Circulation Research. 131
Background: Cardiomyopathy in Duchenne muscular dystrophy (DMD) is a significant driver of disease morbidity and mortality. Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) offer the opportunity to study patient-specific mutations in t
Autor:
Dominic E. Fullenkamp, Alexander B. Willis, Jodi L. Curtin, Ansel P. Amaral, Sloane I. Harris, Paul W. Burridge, Alexis R. Demonbreun, Elizabeth M. McNally
Heart failure is a major source of mortality in Duchenne muscular dystrophy (DMD). DMD arises from mutations that ablate expression of the protein dystrophin, which render the plasma membrane unusually fragile and prone to disruption. In DMD patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad323fe2e09b77ab48e4e7a45ba1faa6
https://doi.org/10.1101/2022.03.09.483528
https://doi.org/10.1101/2022.03.09.483528
Autor:
Sloane I Harris, Paul W. Burridge, Ansel P Amaral, Elizabeth M. McNally, Alexis R. Demonbreun, Jodi L Curtin, Dominic E. Fullenkamp
Publikováno v:
Circulation Research. 129
Heart failure is leading cause of morbidity and mortality in the X-linked disease Duchenne muscular dystrophy (DMD). DMD is due to mutations the gene encoding dystrophin. Dystrophin localizes to the costamere in skeletal and cardiac muscle and is par
Publikováno v:
Eur Heart J
AIMS : Our objective was to better understand the genetic bases of dilated cardiomyopathy (DCM), a leading cause of systolic heart failure. METHODS AND RESULTS : We conducted the largest genome-wide association study performed so far in DCM, with 271
Autor:
Elizabeth M. McNally, Megan J. Puckelwartz, Tess D. Pottinger, Anthony Gacita, Dominic E. Fullenkamp, Joyce C. Ohiri, Marcelo A. Nobrega
Publikováno v:
Circulation
Background: Inherited cardiomyopathy associates with a range of phenotypes, mediated by genetic and nongenetic factors. Noninherited cardiomyopathy also displays varying progression and outcomes. Expression of cardiomyopathy genes is under the regula
Autor:
Marcello A Nobrega, Dominic E. Fullenkamp, Joyce C. Ohiri, Tess D. Pottinger, Anthony Gacita, Megan J. Puckelwartz, Elizabeth M. McNally
Publikováno v:
Circulation. 142
Introduction: Inherited cardiomyopathy is caused by mutations in more than 100 genes. A well-recognized clinical feature of genetic cardiomyopathy is varying phenotypic expression. Even with identical primary mutations, there is a range of clinical o
Autor:
Niels Holten-Andersen, Gareth H. McKinley, Aditya Jaishankar, Lihong He, Genevieve DiMarco, Phillip B. Messersmith, Ka Yee C. Lee, Dominic E. Fullenkamp, Matthew J. Harrington
Publikováno v:
Journal of materials chemistry. B, vol 2, iss 17
MIT web domain
Journal of Materials Chemistry B
MIT web domain
Journal of Materials Chemistry B
Growing evidence supports a critical role of dynamic metal-coordination crosslinking in soft biological material properties such as self-healing and underwater adhesion. Using bio-inspired metal-coordinating polymers, initial efforts to mimic these p
Autor:
Dominic E. Fullenkamp, Dusty R. Miller, Devin G. Barrett, Phillip B. Messersmith, Josh W. Kurutz
Publikováno v:
RSC Adv.. 4:25127-25134
The mussel byssus is a remarkable attachment structure that is formed by injection molding and rapid in situ hardening of concentrated solutions of proteins enriched in the catecholic amino acid 3,4-dihydroxy-L-phenylalanine (DOPA). Fe3+, found in hi
Autor:
Lihong He, Wesley R. Burghardt, Phillip B. Messersmith, Dominic E. Fullenkamp, Devin G. Barrett
Publikováno v:
Macromolecules. 46:1167-1174
Transient network hydrogels cross-linked through histidine-divalent cation coordination bonds were studied by conventional rheologic methods using histidine-modified star poly(ethylene glycol) (PEG) polymers. These materials were inspired by the muss