Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dominic D Shuttleworth"'
Autor:
Sydney R Coffey, Robert M Bragg, Shawn Minnig, Seth A Ament, Jeffrey P Cantle, Anne Glickenhaus, Daniel Shelnut, José M Carrillo, Dominic D Shuttleworth, Julie-Anne Rodier, Kimihiro Noguchi, C Frank Bennett, Nathan D Price, Holly B Kordasiewicz, Jeffrey B Carroll
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175968 (2017)
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease whose predominant neuropathological signature is the selective loss of medium spiny neurons in the striatum. Despite this selective neuropathology, the mutant protein (hunti
Externí odkaz:
https://doaj.org/article/51be1c48c7b241a8b7a44ebe739c65ac
Autor:
William S. Hovander, Sydney R. Coffey, Hardeep S. Tiwana, Madeline Hamilton, Shawn Minnig, Samuel R. W. Legg, Robert M. Bragg, Eva-Mari S. Vik, Dominic D. Shuttleworth, Jeffrey B. Carroll, Jeffrey P. Cantle, Wes T. Solem
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Apathy is one of the most prevalent and progressive psychiatric symptoms in Huntington’s disease (HD) patients. However, preclinical work in HD mouse models tends to focus on molecular and motor, rather than affective, phenotypes. Measuring behavio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a951b5bbd18c339565ac38feb94f3bcf
https://doi.org/10.1038/s41598-018-20607-7
https://doi.org/10.1038/s41598-018-20607-7
Autor:
Robert M. Bragg, Sydney R. Coffey, Rory M. Weston, Seth A. Ament, Jeffrey P. Cantle, Shawn Minnig, Cory C. Funk, Dominic D. Shuttleworth, Emily L. Woods, Bonnie R. Sullivan, Lindsey Jones, Anne Glickenhaus, John S. Anderson, Michael D. Anderson, Stephen B. Dunnett, Vanessa C. Wheeler, Marcy E. MacDonald, Simon P. Brooks, Nathan D. Price, Jeffrey B. Carroll
Publikováno v:
Scientific Reports. 7
Scientific Reports 7: Article number: 41570; published online: 08 February 2017; updated: 28 March 2017 This Article contains a typographical error in the Methods section, under the subheading “Library construction, RNA Sequencing and RNASeq analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1496f6ddb4740ddb933aa001eac951fa
https://doi.org/10.1038/srep44960
https://doi.org/10.1038/srep44960
Autor:
Sydney R. Coffey, Julie Anne Rodier, Kimihiro Noguchi, Dominic D. Shuttleworth, José M. Carrillo, Anne Glickenhaus, C. Frank Bennett, Holly Kordasiewicz, Daniel Shelnut, Jeffrey B. Carroll, Robert M. Bragg, Seth A. Ament, Nathan D. Price, Shawn Minnig
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease whose neuropathological signature is a selective loss of medium spiny neurons in the striatum. Despite this selective neuropathology, the mutant protein (huntingtin) is fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318207b306c865b45f5863ca597c5c5e
Autor:
Lindsey Jones, Sydney R. Coffey, Vanessa C. Wheeler, Marcy E. MacDonald, Anne Glickenhaus, Stephen B. Dunnett, Jeffrey P. Cantle, Seth A. Ament, Rory M. Weston, Emily L. Woods, Robert M. Bragg, Jeffrey B. Carroll, Dominic D. Shuttleworth, Nathan D. Price, Michael D. Anderson, Bonnie R. Sullivan, Simon Philip Brooks, John S. Anderson, Cory C. Funk, Shawn Minnig
Publikováno v:
Scientific Reports
We investigated the appearance and progression of disease-relevant signs in the B6.HttQ111/+mouse, a genetically precise model of the mutation that causes Huntington’s disease (HD). We find that B6.HttQ111/+mice are healthy, show no overt signs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac77a6ea7b8894d52d032ff928730f2
https://pubmed.ncbi.nlm.nih.gov/28350386
https://pubmed.ncbi.nlm.nih.gov/28350386