EP.TH.322Should a concurrent sentinel node biopsy be performed when the preoperative histopathological category of B5c in a breast cancer biopsy is identified?

Autor: Stephanie Jenkins, Dominic Clark

Publikováno v: British Journal of Surgery. 108

Aim To assess the management of sentinel lymph node biopsy (SLNB) in patients with a pre-operative B5c histopathological diagnosis. Method A retrospective study of the decision for SLNB in 31 breast cancer patients with B5c biopsy and their final his

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fce9170cd92a7dfbdf6bb35a3170718
https://doi.org/10.1093/bjs/znab309.042

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models

Autor: Matthew H. Brush, Theodore C. Goldstein, Yvonne A. Evrard, Nathalie Conte, Melissa A. Haendel, Kevin C K Lloyd, Annette T. Byrne, Peter J. Houghton, Carlos Caldas, Amanda L. Christie, Frédéric Amant, Alana L. Welm, Stefan M. Pfister, Mark A. Murakami, Jos Jonkers, Patrick Dunn, Tin Oo Khor, Danielle Greenawalt, Jonathan R. Dry, David M. Weinstock, Sebastian Brabetz, Oscar M. Rueda, Zhiping Gu, Giorgio Inghirami, Dominic Clark, Olivier Duchamp, James M. Olson, Emilie Vinolo, Neal Goodwin, Kristopher K. Frese, Robert J. Wechsler-Reya, Terrence F. Meehan, Daniel S. Peeper, Marcel Kool, Enzo Medico, Jeremy Mason, Stephane Ferretti, Carol J. Bult, Atul J. Butte, S. John Weroha, Els Hermans, Kristel Kemper, Alejandra Bruna, Heidi Dowst, Je Kyung Seong, James H. Doroshow, Livio Trusolino, Michael T. Lewis, Jeffrey Wiser, Dale A. Begley, Steven B. Neuhauser, Helen Parkinson, Debra M. Krupke, Andrea Bertotti

Publikováno v: Cancer research, 77(21), e62-e66. American Association for Cancer Research Inc.
Cancer research, vol 77, iss 21

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research platform to study tumor evolution, mechanisms of drug response and resistance, and tailoring chemotherapeutic approaches for individual patients. The la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6c63e48dd44a0ee2dc83e52b017595
https://doi.org/10.1158/0008-5472.can-17-0582

A case study: semantic integration of gene–disease associations for type 2 diabetes mellitus from literature and biomedical data resources

Autor: Dominic Clark, Christoph Grabmüller, Silvestras Kavaliauskas, Rolf Backofen, Dietrich Rebholz-Schuhmann, Wendy Filsell, Peter Woollard, Samuel Croset

Publikováno v: Drug Discovery Today. 19:882-889

In the Semantic Enrichment of the Scientific Literature (SESL) project, researchers from academia and from life science and publishing companies collaborated in a pre-competitive way to integrate and share information for type 2 diabetes mellitus (T2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67db852bf4993f6958b68c853e0930e
https://doi.org/10.1016/j.drudis.2013.10.024

Medical informatics and bioinformatics: A bibliometric study

Autor: Dominic Clark, J. van der Lei, Ioannis G. Tollis, J.L. Coatrieux, Francesco Beltrame, Luciano Milanesi, Graham Cameron, E.D.H. Barbolla, J.Y. Bansard, Fernando Martin-Sanchez, E.M. van Mulligen, Dietrich Rebholz-Schuhmann

Publikováno v: IEEE Transactions on Information Technology in Biomedicine
IEEE Transactions on Information Technology in Biomedicine, Institute of Electrical and Electronics Engineers, 2007, 11 (3), pp.237-43. ⟨10.1109/TITB.2007.894795⟩
IEEE Transactions on Information Technology in Biomedicine, 2007, 11 (3), pp.237-43. ⟨10.1109/TITB.2007.894795⟩
IEEE transactions on information technology in biomedicine 11 (2007): 237–243. doi:10.1109/TITB.2007.894795
info:cnr-pdr/source/autori:Bansard, J. Y.; Rebholz-Schuhmann, D.; Cameron, G.; Clark, D.; van Mulligen, E.; Beltrame, F.; Del Hoyo Barbolla, E.; Martin-Sanchez, F.; Milanesi, L.; Tollis, I.; van der Lei, J.; Coatrieux, J. L./titolo:Medical informatics and bioinformatics: A bibliometric study/doi:10.1109%2FTITB.2007.894795/rivista:IEEE transactions on information technology in biomedicine/anno:2007/pagina_da:237/pagina_a:243/intervallo_pagine:237–243/volume:11
IEEE Transactions on Information Technology in Biomedicine, 11(3), 237-243. Institute of Electrical and Electronics Engineers Inc.

International audience; This paper reports on an analysis of the bioinformatics and medical informatics literature with the objective to identify upcoming trends that are shared among both research fields to derive benefits from potential collaborati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5c25624d477dda6893c44578630708
https://hdl.handle.net/1765/62750

Antibody informatics for drug discovery

Autor: Kazuyoshi Ikeda, Kazuhisa Tsunoyama, Dominic Clark, John P. Overington, Hiroki Shirai, Paolo Marcatili, Catherine Prades, Randi Vita, Jianqing Xu, Hirayama Kazunori, Marie-Paule Lefranc, Shinji Soga, Bojana Popovic

Publikováno v: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2014, 1844 (11), pp.2002-2015. ⟨10.1016/j.bbapap.2014.07.006⟩

More and more antibody therapeutics are being approved every year, mainly due to their high efficacy and antigen selectivity. However, it is still difficult to identify the antigen, and thereby the function, of an antibody if no other information is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4939ebc5de3b756fa9dc4c8c5e65f3c
https://hal.archives-ouvertes.fr/hal-01088585