Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dominic Boardman"'
Autor:
Manjurul Haque, Dominic Boardman, Avery Lam, Katerine MacDonald, Lieke Sanderink, Qing Huang, Vivian Fung, Sabine Ivison, Majid Mojibian, Megan Levings
Publikováno v:
Bio-Protocol, Vol 12, Iss 23 (2022)
Graft-versus-host disease (GvHD) is a significant complication of allogeneic hematopoietic stem cell transplantation. In order to develop new therapeutic approaches, there is a need to recapitulate GvHD effects in pre-clinical, in vivo systems, such
Externí odkaz:
https://doaj.org/article/0ec4d860f9564164adf2ca40510b19ef
Publikováno v:
Bio-Protocol, Vol 11, Iss 21 (2021)
Regulatory T cells (Tregs) suppress immune responses via a variety of mechanisms and can be used as a cellular therapy to induce tolerance. The function of Tregs is commonly assessed in vitro using assays that measure suppression of effector T cell p
Externí odkaz:
https://doaj.org/article/caa82bce2b4c40d7b18f231c8ad7abdc
Autor:
James L. Reading, Valerie D. Roobrouck, Caroline M. Hull, Pablo Daniel Becker, Jelle Beyens, Alice Valentin-Torres, Dominic Boardman, Estefania Nova Lamperti, Samantha Stubblefield, Giovanna Lombardi, Robert Deans, Anthony E. Ting, Timothy Tree
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Recent clinical experience has demonstrated that adoptive regulatory T (Treg) cell therapy is a safe and feasible strategy to suppress immunopathology via induction of host tolerance to allo- and autoantigens. However, clinical trials continue to be
Externí odkaz:
https://doaj.org/article/25e01aabf5a24ceca4ffe9315b68a013
Autor:
Isaac Rosado-Sánchez, Manjurul Haque, Kevin Salim, Madeleine Speck, Vivian Fung, Dominic Boardman, Majid Mojibian, Giorgio Raimondi, Megan K Levings
Regulatory T cells (Tregs) expressing chimeric antigen receptors (CAR) are a promising tool to promote transplant tolerance. The relationship between CAR structure and Treg function was studied in xenogeneic, immunodeficient mice, revealing advantage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::569d3c8d5eb087dbc241e2a78ee224c8
https://doi.org/10.1101/2022.11.10.516049
https://doi.org/10.1101/2022.11.10.516049
Autor:
Kulachelvy, Ratnasothy, Jacintha, Jacob, Sim, Tung, Dominic, Boardman, Robert Ian, Lechler, Alberto, Sanchez-Fueyo, Marc, Martinez-Llordella, Giovanna, Lombardi
Publikováno v:
American Journal of Transplantation
Regulatory T cells (Tregs) have unique immunosuppressive properties and are essential to ensure effective immunoregulation. In animal models, Tregs have been shown to prevent autoimmune disorders and establish transplantation tolerance. Therefore, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f3f0843a72918ee156dc726b8c6d017
https://pubmed.ncbi.nlm.nih.gov/30748096
https://pubmed.ncbi.nlm.nih.gov/30748096
Autor:
Lesley Ann, Smyth, Kulachelvy, Ratnasothy, Julia Y S, Tsang, Dominic, Boardman, Alice, Warley, Robert, Lechler, Giovanna, Lombardi
Publikováno v:
European journal of immunology. 43(9)
CD4(+)CD25(+)Foxp3(+) Treg cells maintain immunological tolerance. In this study, the possibility that Treg cells control immune responses via the production of secreted membrane vesicles, such as exosomes, was investigated. Exosomes are released by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7a546f064db0d9fd88125f18c5f86d0
https://pubmed.ncbi.nlm.nih.gov/23749427
https://pubmed.ncbi.nlm.nih.gov/23749427