Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Dominic B Rowe"'
Publikováno v:
BMJ Neurology Open, Vol 6, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/b80dd8f7643e4db3b543d1d8267990ad
Autor:
Marta F. Nabais, Simon M. Laws, Tian Lin, Costanza L. Vallerga, Nicola J. Armstrong, Ian P. Blair, John B. Kwok, Karen A. Mather, George D. Mellick, Perminder S. Sachdev, Leanne Wallace, Anjali K. Henders, Ramona A. J. Zwamborn, Paul J. Hop, Katie Lunnon, Ehsan Pishva, Janou A. Y. Roubroeks, Hilkka Soininen, Magda Tsolaki, Patrizia Mecocci, Simon Lovestone, Iwona Kłoszewska, Bruno Vellas, the Australian Imaging Biomarkers and Lifestyle study, the Alzheimer’s Disease Neuroimaging Initiative, Sarah Furlong, Fleur C. Garton, Robert D. Henderson, Susan Mathers, Pamela A. McCombe, Merrilee Needham, Shyuan T. Ngo, Garth Nicholson, Roger Pamphlett, Dominic B. Rowe, Frederik J. Steyn, Kelly L. Williams, Tim J. Anderson, Steven R. Bentley, John Dalrymple-Alford, Javed Fowder, Jacob Gratten, Glenda Halliday, Ian B. Hickie, Martin Kennedy, Simon J. G. Lewis, Grant W. Montgomery, John Pearson, Toni L. Pitcher, Peter Silburn, Futao Zhang, Peter M. Visscher, Jian Yang, Anna J. Stevenson, Robert F. Hillary, Riccardo E. Marioni, Sarah E. Harris, Ian J. Deary, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Wouter van Rheenen, Leonard H. van den Berg, Pamela J. Shaw, Cristopher E. Shaw, Karen E. Morrison, Ammar Al-Chalabi, Jan H. Veldink, Eilis Hannon, Jonathan Mill, Naomi R. Wray, Allan F. McRae
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-30 (2021)
Abstract Background People with neurodegenerative disorders show diverse clinical syndromes, genetic heterogeneity, and distinct brain pathological changes, but studies report overlap between these features. DNA methylation (DNAm) provides a way to e
Externí odkaz:
https://doaj.org/article/201eefeb04d04cf0871060b72f55eedd
Autor:
Zhongbo Chen, Wai Yan Yau, Zane Jaunmuktane, Arianna Tucci, Prasanth Sivakumar, Sarah A. Gagliano Taliun, Chris Turner, Stephanie Efthymiou, Kristina Ibáñez, Roisin Sullivan, Farah Bibi, Alkyoni Athanasiou‐Fragkouli, Thomas Bourinaris, David Zhang, Tamas Revesz, Tammaryn Lashley, Michael DeTure, Dennis W. Dickson, Keith A. Josephs, Ellen Gelpi, Gabor G. Kovacs, Glenda Halliday, Dominic B. Rowe, Ian Blair, Pentti J. Tienari, Anu Suomalainen, Nick C. Fox, Nicholas W. Wood, Andrew J. Lees, Matti J. Haltia, Genomics England Research Consortium, John Hardy, Mina Ryten, Jana Vandrovcova, Henry Houlden
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1716-1725 (2020)
Abstract Neuronal intranuclear inclusion disease (NIID) is a clinically heterogeneous neurodegenerative condition characterized by pathological intranuclear eosinophilic inclusions. A CGG repeat expansion in NOTCH2NLC was recently identified to be as
Externí odkaz:
https://doaj.org/article/bd65c1e21b3a43b093ee1ae9f5b87933
Autor:
Jennifer A. Fifita, Sandrine Chan Moi Fat, Emily P. McCann, Kelly L. Williams, Natalie A. Twine, Denis C. Bauer, Dominic B. Rowe, Roger Pamphlett, Matthew C. Kiernan, Vanessa X. Tan, Ian P. Blair, Gilles J. Guillemin
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The essential amino acid tryptophan (TRP) is the initiating metabolite of the kynurenine pathway (KP), which can be upregulated by inflammatory conditions in cells. Neuroinflammation-triggered activation of the KP and excessive production of the KP m
Externí odkaz:
https://doaj.org/article/10afac3979ec4c8fb35c574b87ed2308
Autor:
Beben Benyamin, Ji He, Qiongyi Zhao, Jacob Gratten, Fleur Garton, Paul J. Leo, Zhijun Liu, Marie Mangelsdorf, Ammar Al-Chalabi, Lisa Anderson, Timothy J. Butler, Lu Chen, Xiang-Ding Chen, Katie Cremin, Hong-Weng Deng, Matthew Devine, Janette Edson, Jennifer A. Fifita, Sarah Furlong, Ying-Ying Han, Jessica Harris, Anjali K. Henders, Rosalind L. Jeffree, Zi-Bing Jin, Zhongshan Li, Ting Li, Mengmeng Li, Yong Lin, Xiaolu Liu, Mhairi Marshall, Emily P. McCann, Bryan J. Mowry, Shyuan T. Ngo, Roger Pamphlett, Shu Ran, David C. Reutens, Dominic B. Rowe, Perminder Sachdev, Sonia Shah, Sharon Song, Li-Jun Tan, Lu Tang, Leonard H. van den Berg, Wouter van Rheenen, Jan H. Veldink, Robyn H. Wallace, Lawrie Wheeler, Kelly L. Williams, Jinyu Wu, Xin Wu, Jian Yang, Weihua Yue, Zong-Hong Zhang, Dai Zhang, Peter G. Noakes, Ian P. Blair, Robert D. Henderson, Pamela A. McCombe, Peter M. Visscher, Huji Xu, Perry F. Bartlett, Matthew A. Brown, Naomi R. Wray, Dongsheng Fan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease. Here, Wray and colleagues identify association of the GPX3-TNIP1 locus with ALS using cross-ethnic meta-analyses.
Externí odkaz:
https://doaj.org/article/522153208176401ebf7630ef7ecef4a7
Autor:
Natalie Grima, Lyndal Henden, Liam G. Fearnley, Dominic B. Rowe, Susan D'Silva, Roger Pamphlett, Lorel Adams, Matthew C. Kiernan, Srestha Mazumder, Hannah C. Timmins, Margaret Zoing, Melanie Bahlo, Ian P. Blair, Kelly L. Williams
Publikováno v:
Neurobiology of Aging. 116:92-95
Sporadic amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a complex genetic architecture. The lengths of two short tandem repeats (STRs), at the NEK1 and STMN2 loci, were recently associated with ALS risk in cohorts of Eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffda3a459215eb676498444ba36d4185
https://doi.org/10.1016/j.neurobiolaging.2022.04.012
https://doi.org/10.1016/j.neurobiolaging.2022.04.012
Autor:
Rodrigo Tomazini Martins, Kristen E. Elstner, Christian Skulina, Omar Rodriguez-Acevedo, John W. Read, Dominic B. Rowe, Nabeel Ibrahim
Publikováno v:
Frontiers in Surgery, Vol 6 (2019)
Purpose: Pre-operative botulinum toxin A (BTA) injection of the lateral obliques aims to facilitate the closure of large ventral hernia defects and decrease the risk of repair breakdown during the critical healing phase. The exact duration of post-op
Externí odkaz:
https://doaj.org/article/5a39193180874a72b6ffae5e5f8c92c4
Short tandem repeat expansions in sporadic amyotrophic lateral sclerosis and frontotemporal dementia
Autor:
Lyndal Henden, Liam G. Fearnley, Natalie Grima, Emily P. McCann, Carol Dobson-Stone, Lauren Fitzpatrick, Kathryn Friend, Lynne Hobson, Sandrine Chan Moi Fat, Dominic B. Rowe, Susan D’Silva, John B. Kwok, Glenda M. Halliday, Matthew C. Kiernan, Srestha Mazumder, Hannah C. Timmins, Margaret Zoing, Roger Pamphlett, Lorel Adams, Melanie Bahlo, Ian P. Blair, Kelly L. Williams
Publikováno v:
Science Advances. 9
Pathogenic short tandem repeat (STR) expansions cause over 20 neurodegenerative diseases. To determine the contribution of STRs in sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), we used ExpansionHunter, REviewer, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f7e922977e297828fc309ac4276362b
https://doi.org/10.1126/sciadv.ade2044
https://doi.org/10.1126/sciadv.ade2044
Publikováno v:
NeuroImage: Clinical, Vol 24, Iss , Pp - (2019)
Objective: To construct a clinical diagnostic biomarker using state-of-the-art microstructural MRI in the motor cortex of people with amyotrophic lateral sclerosis (ALS). Methods: Clinical and MRI data were obtained from 21 ALS patients (aged 54 ± 1
Externí odkaz:
https://doaj.org/article/90bcab37d5cc45a888f6997b29127c51
Autor:
Anjali K. Henders, Pamela A. McCombe, Nigel G. Laing, Perminder S. Sachdev, Allan F. McRae, Garth A. Nicholson, Fleur C. Garton, Beben Benyamin, Wouter van Rheenen, Anna A. E. Vinkhuyzen, Frederik J. Steyn, Restuadi Restuadi, Leanne Wallace, Dominic B. Rowe, Susan Mathers, Robert D. Henderson, Zhihong Zhu, Shyuan T. Ngo, Kelly L. Williams, Tian Lin, Karen A. Mather, Ian P. Blair, Merrilee Needham, Naomi R. Wray, Roger Pamphlett, Peter M. Visscher
Publikováno v:
Eur J Hum Genet
Amyotrophic Lateral Sclerosis (ALS) is recognised to be a complex neurodegenerative disease involving both genetic and non-genetic risk factors. The underlying causes and risk factors for the majority of cases remain unknown; however, ever-larger gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72f7391551108a41dba3e6b07a4f501
https://doi.org/10.1038/s41431-021-00885-y
https://doi.org/10.1038/s41431-021-00885-y