Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dominic A. Gioia"'
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Chronic exposure to alcohol produces adaptations within the basolateral amygdala (BLA) that are associated with the development of anxiety-like behaviors during withdrawal. In part, these adaptations are mediated by plasticity in glutamatergic synaps
Externí odkaz:
https://doaj.org/article/ad75d5b7bd7544fdb90322921bcec9c3
Publikováno v:
Psychopharmacology (Berl)
N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels essential for glutamatergic transmission and plasticity. NMDARs are inhibited by acute ethanol and undergo brain region specific adaptations after chronic alcohol exposure. In p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c920d2d0c4049e8547767c429e38371e
https://doi.org/10.1007/s00213-020-05680-z
https://doi.org/10.1007/s00213-020-05680-z
Autor:
Dominic A Gioia, Brian A. McCool
Publikováno v:
Alcoholism: Clinical and Experimental Research. 41:735-746
BACKGROUND Inbred mouse strains are differentially sensitive to the acute effects of ethanol (EtOH) and are useful tools for examining how unique genomes differentially affect alcohol-related behaviors and physiology. DBA/2J mice have been shown to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3c62dbfd18ff57fc952f5895874549
https://doi.org/10.1111/acer.13343
https://doi.org/10.1111/acer.13343
Publikováno v:
Neuropharmacology
Recent findings from this laboratory demonstrate that ethanol reduces the intrinsic excitability of orbitofrontal cortex (OFC) neurons via activation of strychnine-sensitive glycine receptors. Although the mechanism linking ethanol to the release of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61005cf01a0bccc8d382f57d6fb8a725
https://doi.org/10.1016/j.neuropharm.2021.108600
https://doi.org/10.1016/j.neuropharm.2021.108600
Autor:
Dominic A. Gioia, John J. Woodward
Publikováno v:
eNeuro
The Lateral Orbito-Frontal Cortex (LOFC) is thought to encode information associated with consumption of rewarding substances and is essential for flexible decision making. Indeed, firing patterns of LOFC neurons are modulated following changes in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175ab137073fcf67ec157b07eb9db45e
https://doi.org/10.1523/eneuro.0503-20.2021
https://doi.org/10.1523/eneuro.0503-20.2021
Autor:
Linsey Passarella, Patrick J. Mulholland, Kevin M. Braunscheidel, Erin S. Calipari, Jennifer A. Rinker, Wesley N. Wayman, Dominic A. Gioia, Michaela Hoffman, John J. Woodward
Drugs of abuse are known to alter activity in areas of brain associated with reward, cognition and decision making. Changes in neural activity in these regions that follow repeated exposures to abused substances may underlie the development of addict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b44ef47953e7f87723009ca37eced2
Channelrhodopsins are light activated ion channels used extensively over the past decade to probe the function of genetically defined neuronal populations and distinct neural circuits with high temporal and spatial precision. The widely used Channelr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30156e6190a27ecc6a64535337df053
https://europepmc.org/articles/PMC5975088/
https://europepmc.org/articles/PMC5975088/
C57BL/6J (B6) and DBA/2J (D2) mice are well known to differentially express a number of behavioral phenotypes, including anxiety-like behavior, fear conditioning, and drug self-administration. However, the cellular mechanisms contributing to these di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69337e3ea1efe8f1e044aabcfd2b52c9
https://europepmc.org/articles/PMC5098836/
https://europepmc.org/articles/PMC5098836/
Autor:
Jamie H. Rose, Howard C. Becker, Anushree N. Karkhanis, Rong Chen, Sara R. Jones, Dominic A Gioia, Brian A. McCool, Marcelo F. Lopez
Publikováno v:
International Journal of Neuropsychopharmacology
Background: Chronic ethanol exposure reduces dopamine transmission in the nucleus accumbens, which may contribute to the negative affective symptoms associated with ethanol withdrawal. Kappa opioid receptors have been implicated in withdrawal-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7909aea0aaa66d47f05048caaebef0b7
https://pubmed.ncbi.nlm.nih.gov/26625893
https://pubmed.ncbi.nlm.nih.gov/26625893
Autor:
Caroline E. Bass, Valentina P. Grinevich, Keith Bonin, Jonathan D. Day-Brown, Evgeny A. Budygin, Dominic A Gioia, Jeff L. Weiner, Garret D. Stuber
Publikováno v:
Frontiers in Behavioral Neuroscience
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
There is compelling evidence that acute ethanol exposure stimulates ventral tegmental area (VTA) dopamine cell activity and that VTA-dependent dopamine release in terminal fields within the nucleus accumbens plays an integral role in the regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76027a5b42d3626de8464c841d231b5b