Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dominic A Beckmann"'
Autor:
Branden S Moriarity, Eric P Rahrmann, Dominic A Beckmann, Caitlin B Conboy, Adrienne L Watson, Daniel F Carlson, Erik R Olson, Kendra A Hyland, Scott C Fahrenkrug, R Scott McIvor, David A Largaespada
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96114 (2014)
The advent of Transcription Activator-Like Effector Nucleases (TALENs), and similar technologies such as CRISPR, provide a straightforward and cost effective option for targeted gene knockout (KO). Yet, there is still a need for methods that allow fo
Externí odkaz:
https://doaj.org/article/a67c56a202d14176b28d0ed4ffb24785
Autor:
Christopher L. Moertel, Adrienne L. Watson, Vincent W. Keng, David A. Largaespada, Natalie K. Wolf, Bernat Gel, Dominic A. Beckmann, Margaret H. Collins, Eduard Serra, Margaret R. Wallace, Aaron L. Sarver, Branden S. Moriarity, Kwangmin Choi, Nancy Ratner, Eric P. Rahrmann
Publikováno v:
Nature genetics
Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas of Schwann cell lineage origin that occur sporadically or in association with the inherited syndrome neurofibromatosis type 1. To identify genetic drivers of MPNST development, we used th
Autor:
Ellen G. Melrose, Chase R. Liska, Morito Kurata, Natalie K. Aumann, Dominic A. Beckmann, Branden S. Moriarity, Natashay J. Bailey, Eric P. Rahrmann, David A. Largaespada, Susan K. Rathe, Christopher B. Stoltenberg
Publikováno v:
Scientific Reports
The evolution from microarrays to transcriptome deep-sequencing (RNA-seq) and from RNA interference to gene knockouts using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) and Transcription Activator-Like Effector Nucleases (TALEN
Autor:
David A. Largaespada, Jason B. Bell, Natalie K. Wolf, Dominic A. Beckmann, Luke S. Manlove, Eric P. Rahrmann, Branden S. Moriarity, Touba Khurshid, Vincent W. Keng
Publikováno v:
Nucleic Acids Research
Studying complex biological processes such as cancer development, stem cell induction and transdifferentiation requires the modulation of multiple genes or pathways at one time in a single cell. Herein, we describe straightforward methods for rapid a