Simultaneous Quantification of Amorphous and Crystalline Valsartan in Tablets Using Raman Spectroscopy and Chemometrics Tools

Autor: Domingos,Rafael C., Pinheiro,Adonilson F., Alvarenga Jr.,Benedito R. de, Carneiro,Renato L., Farias,Marco A. S.

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 33, Issue: 2, Pages: 157-162, Published: 24 JAN 2022
Journal of the Brazilian Chemical Society v.33 n.2 2022
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

Valsartan is an antihypertensive active pharmaceutical ingredient (API), it is used in the amorphous state in the commercial products. As amorphous materials are metastable, amorphous valsartan can crystallize to valsartan E, promoting changes in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0a8de2c8bcf6ddc99e4791741db703ed
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022000200157&lng=en&tlng=en

Aplica????o de m??todos de quimiom??tricos de calibra????o multivariada - PLS e iPLS em conjunto com a espectroscopia Raman para an??lise qualitativa e quantitativa de polimorfos de valsartana

Autor: Domingos, Rafael C??ndido

Publikováno v: Biblioteca Digital de Teses e Dissertações da UFAM
Universidade Federal do Amazonas (UFAM)
instacron:UFAM

Submitted by Rafael Domingos (rafaelcdomingos@yahoo.com.br) on 2019-09-08T22:18:51Z No. of bitstreams: 3 Disserta????o Final.pdf: 1757032 bytes, checksum: ab883514fa7a2665e4dd805c6754a07c (MD5) carta deposito.pdf: 104599 bytes, checksum: 2e9a406360e7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::73468f216b1bdd0e41f52c39d1220e56
https://tede.ufam.edu.br/handle/tede/7443