Cisplatin Toxicity Is Mediated by Direct Binding to Toll-Like Receptor 4 through a Mechanism That Is Distinct from Metal Allergens.

Autor: Domingo IK; Departments of Medical Microbiology & Immunology (I.K.D., A.P.B.) and Biochemistry (J.G., M.M.), Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada., Groenendyk J; Departments of Medical Microbiology & Immunology (I.K.D., A.P.B.) and Biochemistry (J.G., M.M.), Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada., Michalak M; Departments of Medical Microbiology & Immunology (I.K.D., A.P.B.) and Biochemistry (J.G., M.M.), Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada., Bhavsar AP; Departments of Medical Microbiology & Immunology (I.K.D., A.P.B.) and Biochemistry (J.G., M.M.), Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada amit.bhavsar@ualberta.ca.

Publikováno v: Molecular pharmacology [Mol Pharmacol] 2023 Mar; Vol. 103 (3), pp. 158-165. Date of Electronic Publication: 2022 Dec 02.

TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study.

Autor: Meijer AJM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. a.j.m.meijer-16@prinsesmaximacentrum.nl., Diepstraten FA; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Langer T; Department of Pediatric Oncology and Hematology, University Hospital for Children and Adolescents, Lübeck, Germany., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Domingo IK; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada., Clemens E; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pediatric Oncology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands., Uitterlinden AG; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., de Vries ACH; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pediatric Oncology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands., van Grotel M; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Vermeij WP; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Ozinga RA; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Binder H; German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.; Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany., Byrne J; Boyne Research Institute, Drogheda, Ireland., van Dulmen-den Broeder E; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; VU Medical Center, Amsterdam, The Netherlands., Garrè ML; Department of Neurooncology, IRCCS Istituto Giannina Gaslini, Genova, Italy., Grabow D; German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Kaatsch P; German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Kaiser M; German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Kenborg L; Childhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark., Winther JF; Childhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health, Aarhus University and University Hospital, Aarhus, Denmark., Rechnitzer C; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Hasle H; Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark., Kepak T; University Hospital Brno, Brno, Czech Republic.; International Clinical Research Center (FNUSA-ICRC), Brno, Czech Republic., Kepakova K; University Hospital Brno, Brno, Czech Republic.; International Clinical Research Center (FNUSA-ICRC), Brno, Czech Republic., Tissing WJE; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pediatric Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van der Kooi ALF; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Obstetrics and Gynecology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands., Kremer LCM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pediatric Oncology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands., Kruseova J; Department of Children Hemato-Oncology, Motol University Hospital Prague, Prague, Czech Republic., Pluijm SMF; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Kuehni CE; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.; Pediatric Hematology and Oncology, University Children's Hospital Bern, University of Bern, Bern, Switzerland., van der Pal HJH; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pediatric Oncology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands., Parfitt R; Department of Phoniatrics and Pedaudiology, University Hospital Münster, Westphalian Wilhelm University, Münster, Germany., Spix C; German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Tillmanns A; Department of Phoniatrics and Pedaudiology, University Hospital Münster, Westphalian Wilhelm University, Münster, Germany., Deuster D; Department of Phoniatrics and Pedaudiology, University Hospital Münster, Westphalian Wilhelm University, Münster, Germany., Matulat P; Department of Phoniatrics and Pedaudiology, University Hospital Münster, Westphalian Wilhelm University, Münster, Germany., Calaminus G; Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany., Hoetink AE; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Utrecht, Utrecht, The Netherlands., Elsner S; Institute of Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany., Gebauer J; Department of Internal Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck, Lübeck, Germany., Haupt R; Epidemiology and Biostatistics Unit and DOPO Clinic, IRCCS Istituto Giannina Gaslini, Genova, Italy., Lackner H; Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria., Blattmann C; Department of Pediatric Oncology/Hematology/Immunology, Stuttgart Cancer Center, Olgahospital, Stuttgart, Germany., Neggers SJCMM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Rassekh SR; BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Division of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Wright GEB; BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Division of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Brooks B; Audiology and Speech Pathology Department, BC Children's Hospital, Vancouver, BC, Canada., Nagtegaal AP; Departement of Otorhinolaryngology, Erasmus Medical Center, Rotterdam, The Netherlands., Drögemöller BI; BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Faculty of Pharmaceutical Sciences, University of British Columbia, British Columbia, Canada., Ross CJD; BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Faculty of Pharmaceutical Sciences, University of British Columbia, British Columbia, Canada., Bhavsar AP; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.; Department of Medical Genetics, University of Alberta, Edmonton, AB, Canada., Am Zehnhoff-Dinnesen AG; Department of Phoniatrics and Pedaudiology, University Hospital Münster, Westphalian Wilhelm University, Münster, Germany., Carleton BC; BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Faculty of Pharmaceutical Sciences, University of British Columbia, British Columbia, Canada., Zolk O; Institute of Clinical Pharmacology, Brandenburg Medical School, Rüdersdorf, Germany., van den Heuvel-Eibrink MM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pediatric Oncology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.

Publikováno v: NPJ precision oncology [NPJ Precis Oncol] 2021 Jul 14; Vol. 5 (1), pp. 64. Date of Electronic Publication: 2021 Jul 14.

Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity-a review of literature evidence.

Autor: Famurewa AC; Department of Medical Biochemistry, Faculty of Basic Medical Sciences, College of Medical Sciences, Alex Ekwueme Federal University Ndufu-Alike Ikwo, Abakaliki, Ebonyi, Nigeria. ademola.famurewa@funai.edu.ng.; Centre for Natural Products Discovery, School of P harmacy and Biomolecular Sciences, Faculty of Science, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK. ademola.famurewa@funai.edu.ng.; Department of Pharmacology, Manipal College of Pharmaceutical Science, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India. ademola.famurewa@funai.edu.ng., George MY; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt., Ukwubile CA; Department of Pharmacognosy, Faculty of Pharmacy, University of Maiduguri, Bama Road, Maiduguri, Borno, Nigeria., Kumar S; Department of Pharmacology, Manipal College of Pharmaceutical Science, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India., Kamal MV; Department of Biochemistry, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India., Belle VS; Department of Biochemistry, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India., Othman EM; Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt.; Cancer Therapy Research Center, Department of Biochemistry-I, Biocenter, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.; Department of Bioinformatics, University of Würzburg, Am Hubland, 97074, BiocenterWürzburg, Germany., Pai SRK; Department of Pharmacology, Manipal College of Pharmaceutical Science, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.

Publikováno v: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine [Biometals] 2024 Dec; Vol. 37 (6), pp. 1325-1378. Date of Electronic Publication: 2024 Sep 30.

Caffeic Acid Phenethyl Ester Suppresses Cytokine- and Chemotherapy-Induced Inflammation in Triple-Negative Breast Cancer via NF-κB Signalling.

Autor: Fosu, Kwadwo, Quarshie, Jude Tetteh, Offei, Nicholas Awuku, Serwaa, Alberta, Tuah, Bernardine, Sobo, Augustine Kojo, Kotei Amon, Justum Nii, Nketiah Sarpong, Kwabena Amofa, Aikins, Anastasia Rosebud

Publikováno v: Natural Product Communications; Nov2024, Vol. 19 Issue 11, p1-14, 14p

hucMSC-derived exosomes protect ovarian reserve and restore ovarian function in cisplatin treated mice.

Autor: Yue Xiao¹, Yue Peng¹, Chi Zhang¹, Wei Liu¹, Kehan Wang¹, Jing Li¹ ljwth@njmu.edu.cn

Publikováno v: Journal of Biomedical Research. Sep2023, Vol. 37 Issue 5, p382-393. 12p.