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Akademický článek

Transition Metal-Free Catalytic C-H Zincation and Alumination.

Autor: Kumar Bisai M; EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom., Łosiewicz J; EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom., Sotorrios L; School of Health Sciences, University of Manchester, Manchester, M13 9PT, United Kingdom., Nichol GS; EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom., Dominey AP; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, United Kingdom., Cowley MJ; EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom., Thomas SP; EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom., Macgregor SA; EaStCHEM School of Chemistry, University of St Andrews, St. Andrews, KY16 9ST, United Kingdom., Ingleson MJ; EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Jun 10; Vol. 63 (24), pp. e202404848. Date of Electronic Publication: 2024 May 06.

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Akademický článek

Investigation of the Formaldehyde-Catalyzed NNitrosation of Dialkyl Amines: An Automated Experimental and Kinetic Modelling Study Using Dibutylamine.

Autor: Diab S; GSK, Park Road, Ware SG12 0DP, United Kingdom. Electronic address: samir.a.diab@gsk.com., Ferrini P; GSK, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom., Dominey AP; GSK, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom., Whiting MP; GSK, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom., Wickens JR; GSK, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom., Ashworth IW; Chemical Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield, SK10 2NA United Kingdom., Rainey TJ; Gilead Sciences, 333 Lakeside Drive, Foster City, CA 94404, United States.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2024 Jun; Vol. 113 (6), pp. 1624-1635. Date of Electronic Publication: 2024 Feb 01.

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Akademický článek

On-column trace-level formation of N-nitrosamine in a liquid chromatography-mass spectrometry analytical system.

Autor: Wickens JR; Medicinal Science and Technology, GlaxoSmithKline R&D, Stevenage, UK., Dominey AP; Medicinal Science and Technology, GlaxoSmithKline R&D, Stevenage, UK.

Publikováno v: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2024 Feb 28; Vol. 38 (4), pp. e9691.

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Akademický článek

Iron-catalysed alkene and heteroarene H/D exchange by reversible protonation of iron-hydride intermediates.

Autor: Britton L; EaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk., Docherty JH; EaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk., Sklyaruk J; EaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk., Cooney J; EaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk., Nichol GS; EaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk., Dominey AP; GSK Medicines Research Centre Stevenage SG1 2NY UK., Thomas SP; EaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk.

Publikováno v: Chemical science [Chem Sci] 2022 Aug 11; Vol. 13 (35), pp. 10291-10298. Date of Electronic Publication: 2022 Aug 11 (Print Publication: 2022).

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Akademický článek

Visible light-mediated Smiles rearrangements and annulations of non-activated aromatics.

Autor: Lawson CA; Chemical Development, GSK, Gunnels Wood Road, Stevenage, SG1 2NY, UK. connor.x.lawson@gsk.com., Dominey AP, Williams GD, Murphy JA

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Sep 29; Vol. 56 (77), pp. 11445-11448.

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Akademický článek

Iron-Catalysed C( sp ² )-H Borylation Enabled by Carboxylate Activation.

Autor: Britton L; EaStCHEM School of Chemistry, University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, UK., Docherty JH; EaStCHEM School of Chemistry, University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, UK., Dominey AP; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK., Thomas SP; EaStCHEM School of Chemistry, University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, UK.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2020 Feb 18; Vol. 25 (4). Date of Electronic Publication: 2020 Feb 18.

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Akademický článek

Cobalt-catalysed Markovnikov selective hydroboration of vinylarenes.

Autor: Peng J; EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK. stephen.thomas@ed.ac.uk., Docherty JH; EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK. stephen.thomas@ed.ac.uk., Dominey AP; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, Hertfordshire, UK., Thomas SP; EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK. stephen.thomas@ed.ac.uk.

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2017 Apr 25; Vol. 53 (34), pp. 4726-4729.

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