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pro vyhledávání: '"Domhnall C. Kelly"'
Autor:
Lara S. Costard, Domhnall C. Kelly, Rachael N. Power, Christopher Hobbs, Sonia Jaskaniec, Valeria Nicolosi, Brenton L. Cavanagh, Caroline M. Curtin, Fergal J. O’Brien
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1219 (2020)
Nonviral vectors offer a safe alternative to viral vectors for gene therapy applications, albeit typically exhibiting lower transfection efficiencies. As a result, there remains a significant need for the development of a nonviral delivery system wit
Externí odkaz:
https://doaj.org/article/8727deab1b764c538410e4e44975b6a4
Publikováno v:
Nature reviews. Rheumatology. 18(2)
Mechanical stimuli have fundamental roles in articular cartilage during health and disease. Chondrocytes respond to the physical properties of the cartilage extracellular matrix (ECM) and the mechanical forces exerted on them during joint loading. In
Autor:
Brenton Cavanagh, Sonia Jaskaniec, Valeria Nicolosi, Rachael N Power, Domhnall C. Kelly, Caroline M. Curtin, Christopher Hobbs, Lara Sophie Costard, Fergal J. O'Brien
Publikováno v:
Pharmaceutics
Volume 12
Issue 12
Pharmaceutics, Vol 12, Iss 1219, p 1219 (2020)
Volume 12
Issue 12
Pharmaceutics, Vol 12, Iss 1219, p 1219 (2020)
Nonviral vectors offer a safe alternative to viral vectors for gene therapy applications, albeit typically exhibiting lower transfection efficiencies. As a result, there remains a significant need for the development of a nonviral delivery system wit
Autor:
Domhnall C. Kelly, Helen O. McCarthy, Irene Mencía Castaño, Fergal J. O'Brien, Nicholas Dunne, Le-Ping Yan, Rukmani Sridharan, Brenton Cavanagh, Mark Lemoine
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 114
Impaired wound healing of diabetic foot ulcers has been linked to high MMP-9 levels at the wound site. Strategies aimed at the simultaneous downregulation of the MMP-9 level in situ and the regeneration of impaired tissue are critical for improved di
Autor:
Fergal J. O'Brien, Rosanne M. Raftery, Caroline M. Curtin, Domhnall C. Kelly, Caitriona M. O'Driscoll
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 37(8)
Recent advances in tissue engineering have made progress toward the development of biomaterials capable of the delivery of growth factors, such as bone morphogenetic proteins, in order to promote enhanced tissue repair. However, controlling the relea
Publikováno v:
Nature Reviews Rheumatology