Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Domenico Tupone"'
Autor:
Timna Hitrec, Flavia Del Vecchio, Luca Alberti, Marco Luppi, Davide Martelli, Alessandra Occhinegro, Emiliana Piscitiello, Ludovico Taddei, Domenico Tupone, Roberto Amici, Matteo Cerri
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
The Raphe Pallidus (RPa) is a brainstem nucleus containing sympathetic premotor neurons that control thermogenesis and modulate cardiovascular function. It receives inputs from various hypothalamic areas, including the Lateral Hypothalamus (LH), a he
Externí odkaz:
https://doaj.org/article/84a1a1a0bf1841db8f124d55d432c749
Autor:
Fabio Squarcio, Timna Hitrec, Emiliana Piscitiello, Matteo Cerri, Catia Giovannini, Davide Martelli, Alessandra Occhinegro, Ludovico Taddei, Domenico Tupone, Roberto Amici, Marco Luppi
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/47609ced8bba432a94194ce83d8d0a9c
Autor:
Fabio Squarcio, Timna Hitrec, Emiliana Piscitiello, Matteo Cerri, Catia Giovannini, Davide Martelli, Alessandra Occhinegro, Ludovico Taddei, Domenico Tupone, Roberto Amici, Marco Luppi
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Hyperphosphorylated Tau protein (PPTau) is the hallmark of tauopathic neurodegeneration. During “synthetic torpor” (ST), a transient hypothermic state which can be induced in rats by the local pharmacological inhibition of the Raphe
Externí odkaz:
https://doaj.org/article/2add5cb63b90442fb366d59effa2e371
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11514 (2023)
The observation of neurogenic fever resulting from subarachnoid hemorrhage (SAH) in animal models is a useful tool for the interpretation of its pathophysiology in humans, which is still a major challenge in the management of neurocritical patients.
Externí odkaz:
https://doaj.org/article/82dd00458045468d872ab58a67f9ab71
Autor:
Domenico Tupone, Justin S. Cetas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Neurogenic fever (NF) after subarachnoid hemorrhage (SAH) is a major cause of morbidity that is associated with poor outcomes and prolonged stay in the neurointensive care unit (NICU). Though SAH is a much more common cause of fever than sep
Externí odkaz:
https://doaj.org/article/692bbb5c5b5b40c4887f827f446996c8
Autor:
Timna Hitrec, Fabio Squarcio, Matteo Cerri, Davide Martelli, Alessandra Occhinegro, Emiliana Piscitiello, Domenico Tupone, Roberto Amici, Marco Luppi
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
Tau is a key protein in neurons, where it affects the dynamics of the microtubule system. The hyperphosphorylation of Tau (PP-Tau) commonly leads to the formation of neurofibrillary tangles, as it occurs in tauopathies, a group of neurodegenerative d
Externí odkaz:
https://doaj.org/article/c9507b0370a7420baca86d117e60068c
Autor:
Marco Luppi, Timna Hitrec, Alessia Di Cristoforo, Fabio Squarcio, Agnese Stanzani, Alessandra Occhinegro, Pierfrancesco Chiavetta, Domenico Tupone, Giovanni Zamboni, Roberto Amici, Matteo Cerri
Publikováno v:
Frontiers in Neuroanatomy, Vol 13 (2019)
Tau protein is of primary importance for many physiological processes in neurons, where it affects the dynamics of the microtubule system. When hyperphosphorylated (PP-Tau), Tau monomers detach from microtubules and tend to aggregate firstly in oligo
Externí odkaz:
https://doaj.org/article/f54765b5f4cd408b82c907478f6d0164
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Numerous data show a reciprocal interaction between REM sleep and thermoregulation. During REM sleep, the function of thermoregulation appears to be impaired; from the other hand, the tonic activation of thermogenesis, such as during cold exposure, s
Externí odkaz:
https://doaj.org/article/b741c97ef1894d18b8eb15eb4b301da9
Autor:
Davide Martelli, Marco Luppi, Matteo Cerri, Domenico Tupone, Marco Mastrotto, Emanuele Perez, Giovanni Zamboni, Roberto Amici
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87793 (2014)
Thermoregulatory responses to temperature changes are not operant during REM sleep (REMS), but fully operant in non-REM sleep and wakefulness. The specificity of the relationship between REMS and the impairment of thermoregulation was tested by elici
Externí odkaz:
https://doaj.org/article/df2a7eaab8884acd84c9c4ed81b05145
Autor:
Matteo Cerri, Flavia Del Vecchio, Marco Mastrotto, Marco Luppi, Davide Martelli, Emanuele Perez, Domenico Tupone, Giovanni Zamboni, Roberto Amici
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112849 (2014)
Neurons within the lateral hypothalamus (LH) are thought to be able to evoke behavioural responses that are coordinated with an adequate level of autonomic activity. Recently, the acute pharmacological inhibition of LH has been shown to depress wakef
Externí odkaz:
https://doaj.org/article/62f8b3e5939441dba7ced6ef50f5be95