Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Domenico L. Di Curzio"'
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-7 (2018)
Abstract Prior research on 3-week hydrocephalic rats showed that behavioral deficits and white matter damage could be reduced by treatment with Ca2+ channel blocker nimodipine. We hypothesized that treatment with nimodipine would be also beneficial t
Externí odkaz:
https://doaj.org/article/a6667fa19a434c98a201a94bf1852745
Autor:
Melanie Martin, Domenico L. Di Curzio, Shenghua Zhu, Heather T. Whittaker, Xin-Min Li, Jonathan D. Thiessen, Frances K. Wiseman, Suzanna Noy, Richard Buist
Publikováno v:
Magnetic Resonance Imaging. 50:26-37
Alzheimer’s disease (AD) pathology causes microstructural changes in the brain. These changes, if quantified with magnetic resonance imaging (MRI), could be studied for use as an early biomarker for AD. The aim of our study was to determine if T(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d519adc59dc56820d2c45f17701a3a
https://doi.org/10.1016/j.mri.2018.03.010
https://doi.org/10.1016/j.mri.2018.03.010
Publikováno v:
Brain Research. 1689:54-62
Memantine is a selective, non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist that has previously been shown to have neuroprotective qualities in some animal models of neurologic disease. We hypothesized that memantine therapy would impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ef73e0f4d7af4d7b1ebef1fe428554
https://doi.org/10.1016/j.brainres.2018.04.001
https://doi.org/10.1016/j.brainres.2018.04.001
Autor:
Domenico L. Di Curzio
Publikováno v:
Open Journal of Modern Neurosurgery. :1-29
Hydrocephalus is a heterogeneous, neurological condition characterized by altered flow of cerebrospinal fluid (CSF) that can occur at any age. Neuropathological changes associated with hydrocephalus are dependent on the age of onset, rate of ventricu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f01aae281fa4f824a7a627e7a18a59f4
https://doi.org/10.4236/ojmn.2018.81001
https://doi.org/10.4236/ojmn.2018.81001
Autor:
Domenico L. Di Curzio
Publikováno v:
Open Journal of Modern Neurosurgery. :57-71
Hydrocephalus is a neurological condition characterized by altered cerebrospinal fluid (CSF) flow leading to an accumulation of CSF inside the cranial vault. Neuropathogenesis associated with hydrocephalus has been elucidated by pathological studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd608da2e32666f3075dfb48c7704e4b
https://doi.org/10.4236/ojmn.2018.81004
https://doi.org/10.4236/ojmn.2018.81004
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-7 (2018)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
Prior research on 3-week hydrocephalic rats showed that behavioral deficits and white matter damage could be reduced by treatment with Ca2+ channel blocker nimodipine. We hypothesized that treatment with nimodipine would be also beneficial to young f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bed31d138bc9f19bdc53e47a8e3a5a
https://doi.org/10.1186/s12987-018-0099-0
https://doi.org/10.1186/s12987-018-0099-0
Publikováno v:
Experimental Neurology. 248:112-128
Hydrocephalus is a neurological condition characterized by altered cerebrospinal fluid (CSF) flow with enlargement of ventricular cavities in the brain. A reliable model of hydrocephalus in gyrencephalic mammals is necessary to test preclinical hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72f70d3cb3b464b64ccaea89442e6b5
https://doi.org/10.1016/j.expneurol.2013.06.004
https://doi.org/10.1016/j.expneurol.2013.06.004
Publikováno v:
Fluids and Barriers of the CNS
Pharmacological interventions have been tested experimentally and clinically to prevent hydrocephalus and avoid the need for shunting beginning in the 1950s. Clinical trials of varied quality have not demonstrated lasting and convincing protective ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6a49238558e7bdb21dcbaae22a0140
https://pubmed.ncbi.nlm.nih.gov/26846184
https://pubmed.ncbi.nlm.nih.gov/26846184
Publikováno v:
Fluids and Barriers of the CNS
Background Oxidative and nitrosylative changes have been shown to occur in conjunction with the hypoxic changes and cellular/axonal damage in hydrocephalic rodent brains. We hypothesized that antioxidant therapy would improve behavioral, neurophysiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072850fc6d762ed8b715d6e26b2a6f36
https://hdl.handle.net/1993/24096
https://hdl.handle.net/1993/24096
Autor:
Melanie Martin, Richard Buist, Marc R. Del Bigio, Benedict C. Albensi, Sheryl L. Herrera, Marzena Z. Kastyak-Ibrahim, Domenico L. Di Curzio
Publikováno v:
Magnetic resonance imaging. 31(9)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is the most common cause of dementia in aging populations. Although senile plaques and neurofibrillary tangles are well-established hallmarks of AD, changes in cerebral white m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236023bd22375f2d48dab5f7fddd9517
https://pubmed.ncbi.nlm.nih.gov/23993791
https://pubmed.ncbi.nlm.nih.gov/23993791