Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Domenico E. Pellegrini-Giampietro"'
Autor:
Costanza Mazzantini, Zahraa El Bourji, Carmen Parisio, Pier Luigi Davolio, Arianna Cocchi, Domenico E. Pellegrini-Giampietro, Elisa Landucci
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 467 (2024)
Cannabis contains over 500 different compounds, including cannabinoids, terpenoids, and flavonoids. Cannabidiol (CBD) is a non-psychoactive constituent, whereas beta-caryophyllene (BCP) is one of most the well-known terpenoids of Cannabis sativa. In
Externí odkaz:
https://doaj.org/article/4fdb154650eb42efbd139c84ff9ca142
Autor:
Elisa Landucci, Costanza Mazzantini, Daniele Lana, Maura Calvani, Giada Magni, Maria Grazia Giovannini, Domenico E. Pellegrini-Giampietro
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105895- (2022)
Background: Epilepsy is one of the most common brain disorder and, despite the possible use of several therapeutic options, many patients continue to have seizures for their entire lifespan and they need new therapeutic approaches. In the last years
Externí odkaz:
https://doaj.org/article/150f3b938b9d427ba6e0e6839029d473
Autor:
Elisa Landucci, Costanza Mazzantini, Maura Calvani, Domenico E. Pellegrini-Giampietro, Maria Camilla Bergonzi
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 578 (2023)
Dry eye disease (DED) is a common ocular disorder characterized by an inadequate lubrication of the eye by tears leading to inflammation and the alteration of the ocular surface. Current treatments are often limited due to their side effects and inef
Externí odkaz:
https://doaj.org/article/613e00b28eb34790bb1c446cc1af8ead
Autor:
Elisa Landucci, Rolando Berlinguer-Palmini, Gilda Baccini, Francesca Boscia, Elisabetta Gerace, Guido Mannaioni, Domenico E. Pellegrini-Giampietro
Publikováno v:
Cells, Vol 11, Iss 19, p 3015 (2022)
In this study, we investigated the cross-talk between mGlu1 and CB1 receptors in modulating GABA hippocampal output in whole-cell voltage clamp recordings in rat hippocampal acute slices, in organotypic hippocampal slices exposed to oxygen and glucos
Externí odkaz:
https://doaj.org/article/e9adff1f19ec4cd3893bef3576d26761
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 937 (2022)
Representing an important cause of long–term disability, term neonatal hypoxic-ischemic encephalopathy (HIE) urgently needs further research aimed at repurposing existing drug as well as developing new therapeutics. Since various experimental in vi
Externí odkaz:
https://doaj.org/article/6c67461013f14256891fb1717e7e82d1
Autor:
Elisa Landucci, Costanza Mazzantini, Daniele Lana, Maria Grazia Giovannini, Domenico E. Pellegrini-Giampietro
Publikováno v:
Toxics, Vol 10, Iss 2, p 48 (2022)
Cannabis derivatives are largely used in the general population for recreational and medical purposes, with the highest prevalence among adolescents, but chronic use and abuse has raised medical concerns. We investigated the prolonged effects of Δ9-
Externí odkaz:
https://doaj.org/article/c1ba2cdc19fc4c50b6cf7456801cf2f2
Autor:
Elisa Landucci, Costanza Mazzantini, Daniele Lana, Pier Luigi Davolio, Maria Grazia Giovannini, Domenico E. Pellegrini-Giampietro
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9773 (2021)
(1) Background: Over the past 10 years, a number of scientific studies have demonstrated the therapeutic potential of cannabinoid compounds present in the Cannabis Sativa and Indica plants. However, their role in mechanisms leading to neurodegenerati
Externí odkaz:
https://doaj.org/article/9784453410674435a8bb2fa468935e85
Autor:
Elisabetta Gerace, Elisa Landucci, Daniele Bani, Flavio Moroni, Guido Mannaioni, Domenico E. Pellegrini-Giampietro
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2019)
Long-term alcohol use can lead to alterations in brain structure and functions and, in some cases, to neurodegeneration. Several mechanisms have been proposed to explain ethanol (EtOH)-related brain injury. One of the most relevant mechanisms of alco
Externí odkaz:
https://doaj.org/article/7613ccd93df349f7bb233453f0f4eda6
Autor:
Elisa Landucci, Costanza Mazzantini, Daniela Buonvicino, Domenico E. Pellegrini-Giampietro, Maria Camilla Bergonzi
Publikováno v:
Molecules, Vol 26, Iss 6, p 1592 (2021)
Experimental evidence indicates that the activation of ionotropic glutamate receptors plays an important role in neurological disorders’ models such as epilepsy, cerebral ischemia and trauma. The glutamate receptor agonist kainic acid (KA) induces
Externí odkaz:
https://doaj.org/article/1004534166274a68ab124c5eae182705
Autor:
Vieri Piazzini, Elisa Landucci, Giulia Graverini, Domenico E. Pellegrini-Giampietro, Anna Rita Bilia, Maria Camilla Bergonzi
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 128 (2018)
(1) Background: Andrographolide (AG) is a natural compound effective for the treatment of inflammation-mediated neurodegenerative disorders. The aim of this investigation was the preparation of liposomes to enhance the penetration into the brain of A
Externí odkaz:
https://doaj.org/article/e341fead9e9a429a98a3ef1b80721298