Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Domenico Conza"'
Autor:
Domenico Conza, Paola Mirra, Francesca Fiory, Luigi Insabato, Antonella Nicolò, Francesco Beguinot, Luca Ulianich
Publikováno v:
Cells, Vol 12, Iss 17, p 2182 (2023)
The biguanide drug metformin is widely used in type 2 diabetes mellitus therapy, due to its ability to decrease serum glucose levels, mainly by reducing hepatic gluconeogenesis and glycogenolysis. A considerable number of studies have shown that metf
Externí odkaz:
https://doaj.org/article/6ecf599bcba3436e8282ee0c4a96c615
Autor:
Alessia Leone, Antonella Nicolò, Immacolata Prevenzano, Federica Zatterale, Michele Longo, Antonella Desiderio, Rosa Spinelli, Michele Campitelli, Domenico Conza, Gregory Alexander Raciti, Francesco Beguinot, Cecilia Nigro, Claudia Miele
Publikováno v:
Cells, Vol 12, Iss 13, p 1741 (2023)
Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO)
Externí odkaz:
https://doaj.org/article/ae86b98c3888430b893c0a56643f7c45
Autor:
Luca Ulianich, Paola Mirra, Corrado Garbi, Gaetano Calì, Domenico Conza, Antonella Sonia Treglia, Alessandro Miraglia, Dario Punzi, Claudia Miele, Gregory Alexander Raciti, Francesco Beguinot, Eduardo Consiglio, Bruno Di Jeso
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The endoplasmic reticulum stress and the unfolded protein response are triggered following an imbalance between protein load and protein folding. Until recently, two possible outcomes of the unfolded protein response have been considered: life or dea
Externí odkaz:
https://doaj.org/article/7cd84bf4c0da44c8a574057c161573b8
Autor:
Domenico Conza, Paola Mirra, Gaetano Calì, Luigi Insabato, Francesca Fiory, Francesco Beguinot, Luca Ulianich
Publikováno v:
Cells, Vol 10, Iss 5, p 1067 (2021)
Multiple lines of evidence suggest that metformin, an antidiabetic drug, exerts anti-tumorigenic effects in different types of cancer. Metformin has been reported to affect cancer cells’ metabolism and proliferation mainly through the activation of
Externí odkaz:
https://doaj.org/article/98e0c931fb1d4054bbf9c7894c921590
Autor:
Miele, Alessia Leone, Antonella Nicolò, Immacolata Prevenzano, Federica Zatterale, Michele Longo, Antonella Desiderio, Rosa Spinelli, Michele Campitelli, Domenico Conza, Gregory Alexander Raciti, Francesco Beguinot, Cecilia Nigro, Claudia
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1741
Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO)
Autor:
Francesca Fiory, Gaetano Calì, Paola Mirra, Luca Ulianich, Luigi Insabato, Domenico Conza, Francesco Beguinot
Publikováno v:
Cells, Vol 10, Iss 1067, p 1067 (2021)
Cells
Volume 10
Issue 5
Cells
Volume 10
Issue 5
Multiple lines of evidence suggest that metformin, an antidiabetic drug, exerts anti-tumorigenic effects in different types of cancer. Metformin has been reported to affect cancer cells’ metabolism and proliferation mainly through the activation of
Autor:
Gaetano Calì, Gregory Alexander Raciti, Corrado Garbi, Claudia Miele, Paola Mirra, Eduardo Consiglio, Antonella Sonia Treglia, Domenico Conza, Alessandro Miraglia, Francesco Beguinot, Bruno Di Jeso, Dario Punzi, Luca Ulianich
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology, Vol 11 (2020)
The endoplasmic reticulum stress and the unfolded protein response are triggered following an imbalance between protein load and protein folding. Until recently, two possible outcomes of the unfolded protein response have been considered: life or dea
Autor:
Vincenzo Cosimato, Gelsomina Luongo, Antonietta Liotti, Paola Mirra, Agnese Secondo, Luigi Insabato, Francesco Beguinot, Gaetano Calì, Luca Ulianich, Daniela Terracciano, Pietro Formisano, Domenico Conza
Publikováno v:
Journal of cellular physiology
233 (2018): 7367–7378. doi:10.1002/jcp.26572
info:cnr-pdr/source/autori:Liotti A.; Cosimato V.; Mirra P.; Cali G.; Conza D.; Secondo A.; Luongo G.; Terracciano D.; Formisano P.; Beguinot F.; Insabato L.; Ulianich L./titolo:Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1%2FGPR40/doi:10.1002%2Fjcp.26572/rivista:Journal of cellular physiology (Print)/anno:2018/pagina_da:7367/pagina_a:7378/intervallo_pagine:7367–7378/volume:233
233 (2018): 7367–7378. doi:10.1002/jcp.26572
info:cnr-pdr/source/autori:Liotti A.; Cosimato V.; Mirra P.; Cali G.; Conza D.; Secondo A.; Luongo G.; Terracciano D.; Formisano P.; Beguinot F.; Insabato L.; Ulianich L./titolo:Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1%2FGPR40/doi:10.1002%2Fjcp.26572/rivista:Journal of cellular physiology (Print)/anno:2018/pagina_da:7367/pagina_a:7378/intervallo_pagine:7367–7378/volume:233
Prostate cancer (PCa) is the most commonly diagnosed malignancy in men and the second leading cause of cancer-related death in industrialized countries. Epidemiologic evidence suggests that obesity promotes aggressive PCa. Recently, a family of Free
Autor:
Silvia Schenone, Paola Mirra, Luca Ulianich, Gaetano Calì, Teresa Tortora, Francesca Fiory, Francesco Beguinot, Rosario Amato, Domenico Conza, Luigi Insabato, Nicola Perrotti
Publikováno v:
Journal of cellular physiology
(2017). doi:10.1002/jcp.25850
info:cnr-pdr/source/autori:Conza, Domenico; Mirra, Paola; Cali, Gaetano; Tortora, Teresa; Insabato, Luigi; Fiory, Francesca; Schenone, Silvia; Amato, Rosario; Beguinot, Francesco; Perrotti, Nicola; Ulianich, Luca/titolo:The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells./doi:10.1002%2Fjcp.25850/rivista:Journal of cellular physiology (Print)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume
(2017). doi:10.1002/jcp.25850
info:cnr-pdr/source/autori:Conza, Domenico; Mirra, Paola; Cali, Gaetano; Tortora, Teresa; Insabato, Luigi; Fiory, Francesca; Schenone, Silvia; Amato, Rosario; Beguinot, Francesco; Perrotti, Nicola; Ulianich, Luca/titolo:The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells./doi:10.1002%2Fjcp.25850/rivista:Journal of cellular physiology (Print)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume
Endometrial cancer is often characterized by PI3K/AKT pathway deregulation. Recently it has been suggested that SGK1, a serine/threonine protein kinase that shares structural and functional similarities with the AKT family, might play a role in cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40139422ccd42e7168d3261bfb16a3e
http://hdl.handle.net/11588/671893
http://hdl.handle.net/11588/671893
Autor:
Francesca Fiory, Domenico Conza, Gaetano Calì, Luca Ulianich, Claudia Miele, Giuseppe Bifulco, Luigi Insabato, Luca Parrillo, Paola Mirra, Bruno Di Jeso, Giuseppe Terrazzano, Gregory Alexander Raciti, Francesco Beguinot
Publikováno v:
Journal of Cellular Physiology. 229:1417-1426
Recent studies have indicated that endoplasmic reticulum stress, the unfolded protein response activation and altered GRP78 expression can play an important role in a variety of tumors development and progression. Very recently we reported for the fi