Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Domenico A. Luongo"'
Autor:
Zora Djuric, Domenico A. Luongo, Daryn Smith, Michael S. Simon, Patricia LoRusso, Lance K. Heilbrun, Silvana Martino
Publikováno v:
Cancer. 77:691-696
BACKGROUND Oxidative DNA damage can result from numerous endogenous metabolic processes as well as from exposure to environmental and dietary oxidants. One important type of oxidative DNA damage is the formation of hydroxylated DNA bases. This type o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c191d41d0f8a94884e206a007064cff
https://doi.org/10.1002/(sici)1097-0142(19960215)77:4<691::aid-cncr15>3.0.co
https://doi.org/10.1002/(sici)1097-0142(19960215)77:4<691::aid-cncr15>3.0.co
Publikováno v:
Cancer Letters. 71:51-56
In vitro metabolism studies have indicated that the tumorigenic environmental pollutant 1,6-dinitropyrene has the potential to bind covalently to DNA and to induce oxidative DNA damage. We have determined if 1,6-dinitropyrene treatment will cause bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d9e446383decbb5768ee4f7392f861
https://doi.org/10.1016/0304-3835(93)90096-r
https://doi.org/10.1016/0304-3835(93)90096-r
Publikováno v:
Chemical Research in Toxicology. 4:687-691
5-(Hydroxymethyl)uracil is a product of oxidative DNA damage. This hydroxylated base was quantified in DNA by GC-MS using either acid or enzymatic hydrolysis of the DNA and isotopically labeled internal standards. Both 5-(hydroxymethyl)uracil and thy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27c8182e058658469500cf58bcc5e7e
https://doi.org/10.1021/tx00024a014
https://doi.org/10.1021/tx00024a014
Publikováno v:
Free radical biologymedicine. 14(5)
DNA damage induced by oxidants includes formation of DNA strand breaks as well as oxidative damage to DNA bases. We quantified both forms of DNA damage concurrently in two model human breast epithelial cell lines treated with hydrogen peroxide to com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6455ad41d5d50eae600f2a60748b7e93
https://pubmed.ncbi.nlm.nih.gov/8349143
https://pubmed.ncbi.nlm.nih.gov/8349143
Autor:
X.W. Chen, Ronald W. Hart, Bruce A. Reading, Ming-Hsiung Lu, Domenico A. Luongo, Sherry M. Lewis, Peter H. Duffy, Zora Djuric, Lance K. Heilbrun
Publikováno v:
Toxicology and applied pharmacology. 115(2)
Increased fat and caloric content of the diet has been associated with increased mammary tumor incidence. The dietary modulation of cellular redox state may be one mechanism behind this association. We have examined the effects of changes in dietary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bb6346fb097368670c6ffcb2f94715
https://pubmed.ncbi.nlm.nih.gov/1641849
https://pubmed.ncbi.nlm.nih.gov/1641849