Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Domenick Argenti"'
Autor:
Alex C. Spyropoulos, John Albanese, Concetta Lipardi, Theodore E. Spiro, Yoriko De Sanctis, Jianfeng Xu, Eunyoung Suh, Domenick Argenti, Elliot S. Barnathan, Wentao Lu, Gary E. Raskob, Jeffrey I. Weitz, Haitao Yang
Publikováno v:
Thrombosis and haemostasis. 120(3)
Patients with renal impairment are at higher risk of thrombosis and bleeding than those with normal renal function. The optimal rivaroxaban dose for thromboprophylaxis in acutely ill medical patients with renal impairment is unknown. MARINER and MAGE
Publikováno v:
Pediatric Diabetes. 19:649-655
Objective Canagliflozin, a sodium glucose cotransporter 2 inhibitor approved for the treatment of adults with type 2 diabetes (T2D), increases urinary glucose excretion (UGE) and lowers plasma glucose (PG) levels by reducing the renal threshold for g
Autor:
Russell Hensel, Donald L. Heald, Domenick Argenti, Carol Bickel, Robert P. Schleimer, Kirk Bordeaux, Bradford K. Jensen
Publikováno v:
The Journal of Clinical Pharmacology. 40:770-780
The principle objective of this study was to characterize the absorption, metabolism, and disposition of orally administered [14C]-triamcinolone acetonide. Six healthy male subjects each received a single 100 microCi (approximately 800 micrograms) or
Publikováno v:
The Journal of Clinical Pharmacology. 40:516-526
The impending phaseout of chlorofluorocarbons as propellants in pressurized metered-dose inhalers used in the treatment of asthma has resulted in the development of alternative devices to deliver drug to the pulmonary airways. These alternative devic
Publikováno v:
American Journal of Therapeutics. 4:3-8
The relationship between plasma concentrations of desmopressin and clotting factors Factor VIII:C (FVIII:C) and von Willebrand Factor (vWF) were explored after a single 15-minute intravenous infusion of desmopressin (0.3 microg/kg) to 28 healthy male
COMPARATIVE PHARMACOKINETICS AND BIOAVAILABILITY OF DILACOR XR AND CARDIZEM CD IN HEALTHY VOLUNTEERS
Publikováno v:
American Journal of Therapeutics. 2:20-30
The objective of this investigation was to compare the single-dose and steady-state pharmacokinetic profiles of Dilacor XR to Cardizem CD. The study enrolled 24 healthy males and was divided into three parts: a single intravenous 25-mg bolus dose of
Autor:
Domenick Argenti, Manuel Vincente Sanchez-Felix, Barbara M. Davit, Jack Cook, Nancy P. Barbour, Francis X. Muller, Amitava Mitra, Shoufeng Li, Alfredo García-Arieta, Vivek S. Purohit, Kerry John Hartauer, James E. Polli, John W. Skoug, Jean-Marie Geoffroy, K. Tang, Paul A. Dickinson
This summary workshop report highlights presentations and over-arching themes from an October 2011 workshop. Discussions focused on best practices in the application of biopharmaceutics in oral drug product development and evolving bioequivalence app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5eef778c08dda5a1a0d8462305a51b
https://europepmc.org/articles/PMC3385831/
https://europepmc.org/articles/PMC3385831/
Publikováno v:
American Journal of Therapeutics. 1:133-139
The objective of this open-label, outpatient, parallel-group investigation was to compare the single-dose and steady-state pharmacokinetic profiles of young (n = 12; x = 41 ± 6 years) and elderly (n = 12; X = 69 ± 4 years) hypertensive patients fol
Publikováno v:
The Journal of urology. 165(5)
We performed a crossover study to determine the relative pharmacokinetic bioavailability and antidiuretic activity of desmopressin in 16 orally hydrated, healthy human subjects.The investigation included 5 study periods with 1 period used to establis
Autor:
Robert P. Schleimer, Carol A. Bickel, Don Heald, Walter C. Hubbard, Domenick Argenti, Mark C. Liu
Publikováno v:
Analytical biochemistry. 290(1)
The intense inherent electron-capture properties of the C21 acetate derivative of triamcinolone acetonide (TAA) under methane chemical ionization mass spectrometric conditions were exploited for the development of a highly sensitive and selective gas