Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Domenicantonio Tropepi"'
Publikováno v:
Annali dell'Istituto Superiore di Sanità, Vol 47, Iss 1, Pp 49-54 (2011)
Neurodegenerative diseases are disabling conditions continuously increasing due to aging of population. A disease modifying therapy that slows or stops disease progression is therefore a major unmet medical need. Unfortunately, research for effective
Externí odkaz:
https://doaj.org/article/22812d8f640546f2815666720e08b58b
Autor:
Domenicantonio Tropepi, Michele Papa, Giorgio Bernardi, Matteo Marti, Emilia Saulle, Michele Morari, Diego Centonze, Antonio Pisani, Paolo Calabresi, Luisa Rossi, Barbara Picconi, Paolo Gubellini
Publikováno v:
Molecular and Cellular Neuroscience. 25:9-20
An impaired complex II (succinate dehydrogenase, SD) striatal mitochondrial activity is one of the prominent metabolic alterations in Huntington's disease (HD), and intoxication with 3-nitropropionic acid (3-NP), an inhibitor of mitochondrial complex
Autor:
Diego Centonze, Paolo Calabresi, Domenicantonio Tropepi, Emilia Saulle, Paola Bonsi, Antonio Pisani, Giorgio Bernardi
Publikováno v:
Neuroreport. 13:115-118
Recent experimental observations indicate that tPA plays a key role in the development of neuronal damage that follows cerebral ischemia and excitotoxicity. In an attempt to clarify how tPA favors ischemia-induced neuronal damage, we performed in vit
Autor:
Barbara Rizzato, Fabrizio Sallustio, Alessio Spinelli, Carlo Andrea Reale, Paolo Stanzione, Enrico Pampana, Silvia Di Legge, Angela Giordano, Costantino Del Giudice, Giacomo Koch, Domenico Samà, Domenicantonio Tropepi, Sebastiano Fabiano, Giulia Misaggi, Matteo Stefanini, Daniel Konda, Costanza Rossi, Giovanni Simonetti, Roberto Gandini, Simone Napolitano, Natale Arnò, Marina Diomedi
Severely impaired patients with persisting intracranial occlusion despite standard treatment with intravenous (IV) administration of recombinant tissue plasminogen activator (rtPA) or presenting beyond the therapeutic window for IV rtPA may be candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e514f11a686f915b605d86aa6fe680
http://hdl.handle.net/2108/74492
http://hdl.handle.net/2108/74492
Autor:
Alessandro Martorana, Roberto Fiori, Giovanni Simonetti, Roberta Semprini, Francesco Massari, Giorgio Bernardi, Domenicantonio Tropepi, Salvatore Masala
Publikováno v:
American Journal of Physical Medicine & Rehabilitation. 83:810-812
Using percutaneous kyphoplasty, we treated a patient with a diagnosis of Guillain-Barré syndrome who complained of an unremitting pain in the spine, refractory to the conventional medical therapy, elicited by pressure over the spinous process, and i
Autor:
Alessandro Stefani, Antonio Pisani, Atticus H. Hainsworth, Mariangela Pierantozzi, Salvatore Galati, Vincenzo Moschella, G. Lunardi, Paolo Stanzione, Silvia Rossi, Livia Brusa, Francesco Fornai, Domenicantonio Tropepi, Ernesto Fedele
To assess possible differences in dopamine metabolism that could parallel disease progression in Parkinson's disease (PD), we measured dopamine (DA) and its metabolites in the cerebrospinal fluid (CSF) in PD patients at different stages of disease: d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03aadebc7221108a2ddcb39b0c769345
http://hdl.handle.net/11567/222097
http://hdl.handle.net/11567/222097
Autor:
Domenicantonio Tropepi, Paolo Mazzone, Antonella Peppe, Maria Giuseppina Palmieri, Mariangela Pierantozzi, Vincenzo Moschella, Paolo Stanzione, Antonio Pisani, Salvatore Galati, Livia Brusa, Maria Grazia Marciani, Alessandro Stefani
Bilateral peduncolopontine nucleus (PPN) and subthalamic nucleus (STN) deep brain stimulation (DBS) was performed in six-advanced Parkinson's disease (PD) patients. We report the effect of both PPN-DBS (25 Hz) and STN-DBS (185 Hz) on patient spinal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac515d44181d753cf7c3d07e5c4f8187
http://hdl.handle.net/2108/218382
http://hdl.handle.net/2108/218382
Autor:
Mariangela Pierantozzi, Antonella Peppe, Alessandro Stefani, Paolo Stanzione, Vincenzo Moschella, Ernesto Fedele, Paolo Mazzone, Giorgio Bernardi, Domenicantonio Tropepi, Livia Brusa, Salvatore Galati, Maurizio Raiteri, Antonio Pisani
Publikováno v:
The European journal of neuroscience. 23(11)
To understand the events underlying the clinical efficacy of deep brain stimulation (DBS) of the subthalamic nucleus (STN), electrophysiological recordings and microdialysis evaluations were carried out in the substantia nigra pars reticulata (SNr),
Autor:
Salvatore Galati, Livia Brusa, Fabrizio Stocchi, Nicola Modugno, Angelo Insola, Paolo Mazzone, Alessandro Stefani, Maria Grazia Altibrandi, Domenicantonio Tropepi
Objectives. Traditional deep brain stimulation (DBS) at the subthalamic nucleus (STN) has proved to be efficacious on core Parkinsonian symptoms. However, very disabling l-dopa-induced abnormal involuntary movements (AIMs) and axial signs are slightl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c52c79aba28986e82b32deeb0eb56c
http://hdl.handle.net/2108/218583
http://hdl.handle.net/2108/218583
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder typically affecting individuals in midlife. HD is characterized by the selective loss of striatal spiny neurons, while large cholinergic interneurons are spared. An impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbc448d3523c4875c99d635d5544aa9
http://hdl.handle.net/2108/27247
http://hdl.handle.net/2108/27247